Frequency, Severity and Impact of Pegylated Interferon Alpha-Associated Flares in Hepatitis D Infection [0.03%]
聚乙二醇干扰素α在乙肝病毒相关性肝炎中的发作频率、严重程度和影响研究
Svenja Hardtke,Cihan Yurdaydin,Florin A Caruntu et al.
Svenja Hardtke et al.
We analysed the frequency, severity and impact of hepatitis flares in a large Phase 2 study investigating pegylated interferon-alfa-2a (PEG-IFNa) for the treatment of hepatitis D. In the HIDIT-II study, 120 patients were treated for 96 week...
Clinical Trial
Journal of viral hepatitis. 2025 Apr;32(4):e70022. DOI:10.1111/jvh.70022 2025
Effects of Different Antiviral Treatments on Liver Inflammation and Fibrosis in Patients With Chronic Hepatitis B [0.03%]
不同抗病毒治疗对慢性乙型肝炎患者肝脏炎症和纤维化的影响
Huiqing Liang,Xiaoting Zheng,Yaoyu Liu et al.
Huiqing Liang et al.
Oral nucleotide analogues (NAs) and peginterferon-α injections are commonly used for the treatment of patients with chronic hepatitis B (CHB). This study aims to evaluate the effects of different antiviral therapies on the degree of liver ...
Development and Validation of a High-Sensitivity Droplet Digital PCR Assay for Serum Hepatitis B Virus DNA Detection [0.03%]
高灵敏度液滴数字PCR乙型肝炎病毒血清DNA检测方法的建立和验证
Rex Wan-Hin Hui,Danny Ka-Ho Wong,Lung-Yi Mak et al.
Rex Wan-Hin Hui et al.
Real-time polymerase chain reaction (PCR) is the current standard for serum HBV DNA measurement. However, conventional real-time PCR assays have technical limitations, and are not sensitive enough to detect low-level residual viremia in chr...
Impact of HBV Infection in Couples on In Vitro Fertilisation-Embryo Transfer Outcomes and Clinical Characteristics of Newborns: A Retrospective Study Based on 3900 Infertile Couples [0.03%]
HBV感染对体外受精-胚胎移植结局及新生儿临床特征的影响：基于3900例不育夫妇的回顾性研究
Kaiwen Xue,Leji Wen,Xiaolei Ji et al.
Kaiwen Xue et al.
To investigate the effects of chronic HBV infection on the outcome of in vitro fertilisation-embryo transfer and clinical characteristics of newborns, as well as the factors influencing different outcomes of in vitro fertilisation-embryo tr...
Validation Study of Scores Predicting Hepatocellular Carcinoma Risk in Chronic Hepatitis B Patients Treated With Nucleos(t)ide Analogues [0.03%]
核苷(酸)类似物治疗的慢性乙型肝炎患者肝细胞癌风险预测评分的有效性研究
Jun Inoue,Shinichiro Minami,Kazumichi Abe et al.
Jun Inoue et al.
Chronic hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC) worldwide. Nucleos(t)ide analogues (NAs) are widely used in chronically HBV-infected patients, but the risk of HCC still remains in NA-treated pa...
Systematic Screening for Hepatitis B, C, and HIV and Linkage to Care in Patients With Mental Health Disorders Admitted to the Emergency Department [0.03%]
系统筛查乙型肝炎、丙型肝炎和HIV并建立与急诊科精神疾病患者护理的联系
Prabakar Vaittinada Ayar,Jamal Abdelkader,Matthieu Gay et al.
Prabakar Vaittinada Ayar et al.
People with mental health disorders have a significant lack of physical health care. They also have higher rates of medical co-morbidity. The aim of this study was to assess the feasibility and the linkage to care of systematic screening fo...
Observational Study
Journal of viral hepatitis. 2025 Apr;32(4):e70018. DOI:10.1111/jvh.70018 2025
Enhancing Hepatitis C Management: Mortality Trends and Disparities in the US by Sex, Age Group, Race/Ethnicity and Region (1999-2020) [0.03%]
提高丙型肝炎的管理：按性别、年龄组、种族/族裔和地区的死亡率趋势和差异（1999-2020年）
Sophia Ahmed,Muhammad Asfandyar Nadir,Hanzala Ahmed Farooqi et al.
Sophia Ahmed et al.
Hepatitis C virus (HCV) infection affects approximately 3.9 million people in the United States (U.S.), leading to 8000 to 10,000 deaths annually. Despite advancements in curative treatments since 2014, effective strategies targeting high-r...
Hepatocytes and Hepatic Stellate Cells Carry Different Levels of DNA Damage due to Their Sensitivity to Oxidative Stress in Chronic Hepatitis B [0.03%]
乙型肝炎中肝脏细胞和肝星状细胞携带不同水平的DNA损伤，由于其对氧化应激的敏感性不同
Yansong Zhang,Danjing Jin,Hongqiong Zhu et al.
Yansong Zhang et al.
Hepatocellular carcinoma (HCC) and liver cirrhosis (LC) occur in spite of current antiviral therapies in patients with chronic hepatitis (CHB). It is not yet known why HCC and LC are related to hepatocytes and hepatic stellate cells (HSCs),...
Bera Enes Seyrek,Kubra Aykac,İncinur Saltık Temizel et al.
Bera Enes Seyrek et al.
Human Bocavirus (HBoV) is an emerging pathogen linked to respiratory and gastrointestinal infections in children. While its role in respiratory diseases is established, its association with liver dysfunction remains unclear. This study pres...
Case Reports
Journal of viral hepatitis. 2025 Mar;32(3):e70013. DOI:10.1111/jvh.70013 2025
Screening, Prevalence and Management of Chronic Viral Hepatitis C in Mental Health Setting: Towards the Eradication of A Forgotten Reservoir [0.03%]
精神健康机构中慢性病毒性丙型肝炎的筛查、流行和管理：走向根除被遗忘的病毒储备库
Sonia Chelouah,Harmonie Nna,Paul Angijiro et al.
Sonia Chelouah et al.
The rate of HCV infection is higher in people with psychiatric conditions than in the general population. However, access to somatic care for populations with mental or dual diagnoses remains insufficient. These circumstances could constitu...