Droplet Digital PCR: A Powerful Tool for Accurate Quantification of Hepatitis D Virus RNA Levels and Verification of Detection Limits [0.03%]
液滴数字PCR技术在乙肝病毒DNA绝对定量及检出限验证中的应用研究
L Sandmann,L Windzio,B Bremer et al.
L Sandmann et al.
Reliable quantification of hepatitis D virus (HDV) RNA levels is necessary for initiating and guiding antiviral treatment. The aim of this work is to develop and validate a digital PCR method for the accurate quantification of HDV RNA, incl...
Chronic Hepatitis B Patients Referred for Liver Transplantation After Nucleos(t)ide Analog Cessation [0.03%]
停止核苷(酸)类似物抗病毒治疗后转诊行肝移植的慢性乙型肝炎患者
Grishma Hirode,Mai Kilany,Steven Pi et al.
Grishma Hirode et al.
Nucleos(t)ide analogs (NAs) provide prolonged viral suppression with favourable clinical outcomes in chronic hepatitis B (CHB) patients. Characterisation of adverse hepatic events after NA cessation leading to liver transplantation (LT) is ...
Identifying Risk Factors for Hepatocellular Carcinoma in Patients With Delta Hepatitis: A Prognostic Study [0.03%]
丁型肝炎患者肝细胞癌的危险因素识别：一项预后研究
Speranta Iacob,Mirela Chitul,Diana Stan et al.
Speranta Iacob et al.
Given that delta hepatitis is associated with a 2-6 times higher risk for hepatocellular carcinoma (HCC) compared to HBV monoinfection, we aimed to identify the negative prognostic factors for complications associated with HDV infection (pa...
Host Factor SRSF7 Promotes HBV Replication Through Binding to and Stabilising Viral pgRNA [0.03%]
宿主因子SRSF7通过与乙肝病毒pgRNA结合并增强其稳定性来促进HBV复制
Yu Peng,Yuxin Song,Xin Liu et al.
Yu Peng et al.
Hepatitis B virus (HBV) is the primary etiological agent of chronic hepatitis B (CHB) infection, posing a serious threat to human health. The pregenomic RNA (pgRNA) of HBV is the template for HBV reverse transcription, and the epsilon stem-...
Elizabeth M Marlowe,Brooke E Swanson,Susan E Realegeno et al.
Elizabeth M Marlowe et al.
Hepatitis D virus (HDV) affects nearly 5% of people globally who are chronically infected with hepatitis B virus, according to the World Health Organisation. The prevalence of HDV in the United States is considered lower than in other count...
A Government-Led, Patient-Centric Strategy to Re-Engage Diagnosed but Untreated Hepatitis C Patients in Yunnan Province, China [0.03%]
我国云南省政府主导、以患者为中心的策略促使丙型肝炎诊断患者重新接受治疗项目
Shifu Li,Wenbin Dong,Yingni Yu et al.
Shifu Li et al.
Diagnosed but untreated (DBU) hepatitis C virus (HCV) infected patients are a key group for HCV elimination efforts. This study aims to pilot a government-led, multi-sectoral approach to universal patient recall and treatment mobilisation i...
Cost-Effectiveness of Universal Screen-and-Treat Strategies for Reducing Morbidity and Mortality of Chronic Hepatitis B in a High-Endemicity City [0.03%]
在高乙肝病毒流行城市中筛查和治疗慢性乙型肝炎的经济效益分析
Ngai Sze Wong,Denise Pui-Chung Chan,Grace Lai-Hung Wong et al.
Ngai Sze Wong et al.
In the setting of high hepatitis B virus (HBV) endemicity, we studied the cost-effectiveness of universal HBV screen-and-treat strategies for averting HBV-related morbidity and mortality in Hong Kong, where diagnosis and treatment coverages...
Global Burden and Trends of Acute Hepatitis C From 1990 to 2021: An Analysis Based on the 2021 Global Burden of Disease Study [0.03%]
1990年至2021年急性丙型肝炎的全球负担和趋势：基于2021年全球疾病负担研究的分析
Xinwei Wang,Xipeng Yan,Baoren He et al.
Xinwei Wang et al.
Acute hepatitis C (AHC) represents a considerable challenge to global public health, although direct-acting antiviral (DAA) therapy has substantially improved therapeutic outcomes for hepatitis C virus infection. Data were exclusively obtai...
Sensitivity Analysis of Hepatitis B and C Mortality in England Using Data Linkage: Meeting the WHO Elimination Threshold for Mortality [0.03%]
使用数据链接对英国的乙型和丙型肝炎死亡率进行敏感性分析：满足WHO对死亡率消除阈值的要求
Annabel A Powell,Annastella Costella,Rachel Roche et al.
Annabel A Powell et al.
The United Kingdom, along with many other countries, is working towards eliminating viral hepatitis as a public health threat by 2030, with a combined mortality target of less than or equal to six deaths per 100,000 population. The current ...
Prevalence of Hepatitis C Among Migrants: A Systematic Review and Meta-Analysis [0.03%]
移民中丙型肝炎的流行率：系统评价和荟萃分析
Jiajun Sun,Matthew Kelly,Tsheten Tsheten et al.
Jiajun Sun et al.
The World Health Organisation has targeted the Hepatitis C virus (HCV) to be eliminated as a public health threat by 2030. Equitable access to HCV testing and treatment services is important in achieving this goal. Migrants often face barri...