Social jet lag is associated with incident cardiovascular disease independent of sleep duration and cardiac genetic risk [0.03%]
社会性时差与心血管疾病独立相关,不受睡眠时间和心脏遗传风险影响
Neeraj Kumar,Sairam Krishnamurthy
Neeraj Kumar
Background: Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, yet many events occur in individuals not fully explained by traditional clinical and lifestyle factors. Social jet lag reflects mi...
Multicenter validation of a severity index model for predicting postoperative acute kidney injury [0.03%]
多中心急性肾损伤后病情严重程度指数模型的验证研究
Ji-Hoon Sim,Ah Ran Oh,Jaeyeon Chung et al.
Ji-Hoon Sim et al.
Background: Existing models for predicting postoperative acute kidney injury (AKI) after non-cardiac surgery are often complex and insufficiently validated for broad clinical use. We developed and externally validated a s...
The changing epidemiology of human type 2 diabetes-associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities [0.03%]
与2型糖尿病相关的动脉粥样硬化流行病学的变迁:病理生理机制及新的治疗可能
Dania Al-Sharify,Jiangming Sun,Andreas Edsfeldt
Dania Al-Sharify
Type 2 diabetes (T2D) is a major global health concern strongly associated with atherosclerosis and subsequent macrovascular complications. These complications are the leading cause of death among T2D patients. Despite a decline in cardiova...
Angiopoietin-like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride-rich lipoproteins in humans [0.03%]
人类中血管生成素样蛋白3完全和部分缺乏显著加速富含甘油三酯脂蛋白中载脂蛋白B48和B100代谢
Marcello Arca,Elias Björnson,Laura DErasmo et al.
Marcello Arca et al.
Background: Angiopoietin-like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be expl...
Authors' reply: Myasthenia gravis following the initiation of statin therapy [0.03%]
作者回复:他汀类药物治疗后发生的重症肌无力
Vincent Ka Chun Yan,Wanchun Xu,Yuta Taniguchi et al.
Vincent Ka Chun Yan et al.
Sha Zeng,ZhengRong Shi
Sha Zeng
Brain pathology in relation to somatic diseases: Exploring the body-brain crosstalk [0.03%]
脑与躯体疾病的病理关系:探索身心相互作用
G Grande,M Valletta,F Gasparini et al.
G Grande et al.
Several somatic diseases have been consistently linked with an increased dementia risk. However, the underlying neuropathological substrates remain poorly characterized. This narrative review aims to summarize evidence on the association be...
Artur Fedorowski
Artur Fedorowski
Aspirin or non-steroidal anti-inflammatory drug initiation and subsequent bladder cancer evaluation [0.03%]
关于阿司匹林或非甾体抗炎药的起始使用和后续膀胱癌评估的研究
Malene Söth Hansen,Lars Dyrskjøt,Uffe Heide-Jørgensen et al.
Malene Söth Hansen et al.
Background: Whether aspirin or non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) initiation may unmask unknown bladder cancers (BCs) by hematuria remains controversial. ...
Nikhita Santebennur,Jorge Gutierrez,Abhinav Talwar et al.
Nikhita Santebennur et al.