Evaluation of the Tocilizumab therapy in human cancers: Latest evidence and clinical potential [0.03%]
托珠单抗在人类癌症治疗中的疗效评估：最新证据和临床潜力
Kimia Ghasemi,Kosar Ghasemi
Kimia Ghasemi
Tocilizumab (Actemra®), as the first human interleukin-6 receptor (IL-6R) antagonist, has been used in treating moderate to severe active rheumatoid arthritis (RA) patients who were undertreatment with one or more disease-modifying anti-rh...
Risk factors for high-dose methotrexate associated toxicities in patients with primary central nervous system lymphoma [0.03%]
高剂量甲氨蝶呤相关毒性的原发中枢神经系统淋巴瘤的危险因素分析
Kai Sun,Hongwei Tao,Tianling Ding et al.
Kai Sun et al.
What is known and objective: Methotrexate (MTX) is an antimetabolic antitumor drug with high individual differences and may lead to severe toxicities in a considerable number of patients. This study aimed to explore the f...
Prevalence and risk factors associated with readmission with acute kidney injury in patients receiving vancomycin outpatient parenteral antimicrobial therapy [0.03%]
静脉注射万古霉素门诊抗生素治疗患者急性肾损伤再入院的流行率及危险因素
Yasir Hamad,Katelin B Nickel,Yvonne J Burnett et al.
Yasir Hamad et al.
Introduction: Vancomycin is commonly used during outpatient parenteral antimicrobial therapy (OPAT). Therapeutic drug monitoring (TDM) of vancomycin is recommended to ensure effective and safe therapy, as use has been ass...
Management of drug-induced neutropenia, thrombocytopenia, and anaemia after solid organ transplantation: A comprehensive review [0.03%]
器官移植后药物引起的中性粒细胞减少症、血小板减少症和贫血的管理：全面回顾
Hananeh Baradaran,Arezou Hashem Zadeh,Simin Dashti-Khavidaki et al.
Hananeh Baradaran et al.
What is known and objective: Advances in the development of more effective immunosuppressive drugs have increased graft survival and drug induced adverse effects. Haematological complications including neutropenia, thromb...
Heparin-induced persistent hyperthermia with recurrent hyponatremia in hip fracture: Case report and review of literature [0.03%]
肝素引起的髋部骨折持续发热和反复低钠血症的病例报告及文献回顾
Zongyuan Huang,Xin Wu,Shuai Zhang et al.
Zongyuan Huang et al.
What is known and objective: Heparin is a commonly used anticoagulant in clinic. Persistent hyperthermia with recurrent hyponatremia caused by heparin is an extremely rare drug fever, which is difficult to judge in the ea...
The Inflation Reduction Act: A boon for the generic and biosimilar industry [0.03%]
通胀削减法案将利好仿制药和生物类似药产业
Sarfaraz K Niazi
Sarfaraz K Niazi
What is known and objective: After more than a year of negotiation, a $740 billion climate and health care bill known as The Inflation Reduction Act (IRA) became law on 16 August 2022. In addition to its impact on the env...
Double filtration plasmapheresis for hypertriglyceridemic acute pancreatitis caused by fat overload syndrome [0.03%]
双滤过血浆置换治疗脂肪负荷综合征所致高甘油三酯血症急性胰腺炎
Chunxi Wu,Ting Xu,Zhongmei Yi et al.
Chunxi Wu et al.
What is known and objective: Severe hypertriglyceridemia (HTG) can cause acute pancreatitis (AP). Case summary: We report a patient wit...
Acinetobacter baumannii: Pathogenesis, virulence factors, novel therapeutic options and mechanisms of resistance to antimicrobial agents with emphasis on tigecycline [0.03%]
鲍曼不动杆菌的致病机制、毒力因素、新型治疗手段及其耐药机理，特别是对替加环素的耐药性
Razieh Dehbanipour,Zohreh Ghalavand
Razieh Dehbanipour
What is known and objective: Acinetobacter baumannii is one of the most important nosocomial pathogens with the ability to cause infections such as meningitis, pneumonia, urinary tract, septicaemia and wound infections. A...
Safety of trastuzumab deruxtecan: A meta-analysis and pharmacovigilance study [0.03%]
德鲁替康的安全性分析及药物警戒研究meta分析
Zihan Guo,Yunlan Ding,Mengmeng Wang et al.
Zihan Guo et al.
What is known and objective: This study aimed to explore the safety profile of trastuzumab deruxtecan (T-DXd, formerly DS-8201a) using multi-source medical data. ...
The effect of the clinical pharmacist in minimizing drug-related problems and related costs in the intensive care unit in Turkey: A non-randomized controlled study [0.03%]
土耳其临床药剂师在重症监护病房中减少药物相关问题和相关成本的作用：一项非随机对照研究
Yunus Emre Ayhan,Sait Karakurt,Mesut Sancar
Yunus Emre Ayhan
What is known and objective: Drug-related problems (DRPs) are common in hospitalized patients in intensive care unit (ICU). The aim of the study is to reduce DRPs and associated costs with clinical pharmacist's (CP) recom...