Christian Kroll,Arya Zandvakili
Christian Kroll
What is known and objective: Central diabetes insipidus (DI) is a complex disease that requires firm adherence to desmopressin therapy. There is little information on the onset of hypernatremia after withdrawal of desmopr...
Central nervous system adverse events of ceftazidime/avibactam: A retrospective study using Food and Drug Administration Adverse Event Reporting System [0.03%]
头孢他啶/阿维巴克特的中枢神经系统不良事件：一项使用美国食品药品监督管理局不良事件报告系统的回顾性研究
Xiaolong Guo,Mingxing Guo,Jiyang Li et al.
Xiaolong Guo et al.
What is known and objective: Many antibiotics are well known for being associated with adverse events (AEs) of central nervous system, ceftazidime/avibactam (CAZ/AVI) is a novel β-lactam/β-lactamase inhibitor combinatio...
Comparison of vancomycin area under the concentration-time curve (AUC) using two-point pharmacokinetics versus two open-access online single-concentration vancomycin calculators [0.03%]
两种两点药代动力学与两种开放访问的在线单浓度万古霉素计算器所得万古霉素曲线下面积(AUC)的比较
Nicole M Ondrush,Rejs Ademovic,Robert W Seabury et al.
Nicole M Ondrush et al.
What is known and objective: Current vancomycin monitoring guidelines recommend the use of area under the concentration-time curve (AUC24 ) monitoring in patients with serious Methicillin-Resistant Staphylococcus aureus (...
CytoSorb haemoadsorption for removal of apixaban-A proof-of-concept pilot case for a randomized controlled trial [0.03%]
用于清除阿哌沙班的 CytoSorb 血液吸附 - 随机临床试验的概念验证试点案例
Marianna Buonocore,Steffen Rex,Karlien Degezelle et al.
Marianna Buonocore et al.
What is known and objective: Emergent cardiac surgery in patients under anticoagulant therapy is still a major point of concern. Recently approved reversal agents are often not available or not suitable in the cardiac sur...
Randomized Controlled Trial
Journal of clinical pharmacy and therapeutics. 2022 Dec;47(12):2373-2375. DOI:10.1111/jcpt.13802 2022
Efficacy and safety of rituximab biosimilars or reference product as first-line treatment in patients with low-tumour-burden follicular lymphoma: A systematic review and meta-analysis [0.03%]
利妥昔单抗生物类似药或参考产品作为低肿瘤负担滤泡性淋巴瘤一线治疗的疗效和安全性：系统回顾和荟萃分析
Liu Yang,Zhiwei Zheng,Na Li et al.
Liu Yang et al.
What is known and objective: The role of rituximab in the first-line treatment of low-tumour-burden follicular lymphoma (LTB-FL) has been supported by a large number of data. However, whether rituximab biosimilars have th...
Dosage optimization of voriconazole in children with haematological malignancies based on population pharmacokinetics [0.03%]
基于人群药动学的血液系统恶性肿瘤儿童患者伏立康唑剂量优化
Yun Wu,Chunle Lv,Dongni Wu et al.
Yun Wu et al.
What is known and objectives: Voriconazole has a complex pharmacokinetic profile and exhibits different pharmacokinetic characteristics in adults and children. Nevertheless, few studies have been conducted on the populati...
Remimazolam versus propofol for deep sedation/anaesthesia in upper gastrointestinal endoscopy in elderly patients: A multicenter, randomized controlled trial [0.03%]
老年人上消化道内镜诊疗中深度镇静/麻醉使用瑞马唑仑与丙泊酚的比较：一项多中心随机对照试验
Kejian Lu,Shanshan Wei,Wenwen Ling et al.
Kejian Lu et al.
Background and objective: Propofol is the most commonly used sedative in gastrointestinal endoscopic procedures, but is associated with cardiorespiratory suppression, particularly in elderly patients. Remimazolam is a new...
Randomized Controlled Trial
Journal of clinical pharmacy and therapeutics. 2022 Dec;47(12):2230-2236. DOI:10.1111/jcpt.13797 2022
The correlation between paclitaxel chemotoxicity and the plasma albumin level in cancer patients [0.03%]
癌症患者紫杉醇化学毒性与血浆白蛋白水平的相关性研究
Weibin Fan,Weiming Yin,Feng Zhou et al.
Weibin Fan et al.
What is known and objective: The aim of this study was to evaluate the pharmacokinetics of paclitaxel in cancer patients with hypoalbuminemia following paclitaxel-containing chemotherapy and to provide a reference for the...
Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis in adults: A meta-analysis [0.03%]
成人侵袭性肺曲霉病患者支气管肺泡灌洗液曲霉菌半乳甘露聚糖检测诊断价值的meta分析
Chang Li,Lin Sun,Yin Liu et al.
Chang Li et al.
What is known and objective: To analyse the diagnostic accuracy of bronchoalveolar lavage fluid galactomannan (BALF-GM) assay for invasive pulmonary aspergillosis (IPA) in adults to determine the optimal diagnostic cut-of...
The effect of changing to Bictegravir on lipids using real world data: A brief report [0.03%]
基于真实世界数据的药物换用对血脂影响的简要研究报告:BIC替拉韦更换用药分析
Thomas Heseltine,Elen Hughes,Jean Mathew et al.
Thomas Heseltine et al.
What is known and objective: Cardiovascular disease is of increasing concern in patients living with HIV. The significant advancement in antiretroviral treatment has ensured that patients are now succumbing to traditional...