Severe lung injury induced by CD38 monoclonal antibody Daratumumab and bortezomib-containing regimen in a patient with preexisting interstitial lung disease: a case report and literature review [0.03%]
具有先前存在的间质性肺病的患者的CD38单克隆抗体Daratumumab和含有Bortezomib的治疗方案诱导的严重肺损伤：病例报告及文献回顾
Meng Chen,Lei Zhao,Fang Yao et al.
Meng Chen et al.
What is known and objective: Daratumumab, an anti-CD38 monoclonalantibody, is a safe and effective antibody used in the treatment of multiple myeloma (MM), which is rarely reported to cause severe pulmonary complications....
Six months multicentre pilot open label single-arm study to evaluate patient experience, acceptability and satisfaction of switching certolizumab pegol from a prefilled syringe or autoinjection pen to an AVA® e-Device in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis patients [0.03%]
在类风湿性关节炎，强直性脊柱炎和银屑病性关节炎患者中从预填充注射器或自动注射笔切换到AVA®e设备的 certolizumab pegol 的六月多中心试点开放单臂研究以评估患者体验，耐受性和满意度
Joaquin Borrás-Blasco,Esther Vicente-Escrig,Francisco José Rodríguez-Lucena et al.
Joaquin Borrás-Blasco et al.
What is known and objective: The study aimed to assess acceptability and patient experience of Certolizumab (CZP) self-injection with AVA® and clarify patient device preference after switching CZP from the syringe or aut...
Progress of triazole antifungal agent posaconazole in individualized therapy [0.03%]
三唑类抗真菌药物泊沙康唑在个体化治疗中的进展
Yishuo Shu,Yinping Shi,Yilei Yang et al.
Yishuo Shu et al.
What is known and objective: Posaconazole is the second-generation triazole antifungal agent with widespread clinical application. Posaconazole exposure is influenced by various factors such as drug interactions, disease ...
VANCOmycin dose adjustments comparing trough levels to the ratio of the area under de curve to the minimum inhibitory concentration method using a BAYESian approach: A feasibility study [0.03%]
利用贝叶斯方法比较谷浓度与曲线下的面积与最小抑菌浓度比值进行万古霉素剂量调整：可行性研究
Véronique Bilodeau,Justine Huot,Catherine Perreault et al.
Véronique Bilodeau et al.
WHAT IS KNOWN AND OBJECTIVE?: The latest published guidelines advocate for the area under the concentration-time curve to minimal inhibitory concentration (AUC0-24h /MIC) estimated with bayesian calculations. This recommended pharmacokineti...
The efficacy and safety of intravenous tirofiban in the treatment of acute ischemic stroke patients with early neurological deterioration [0.03%]
静脉使用替罗非班治疗急性缺血性卒中伴有早期神经功能恶化患者的疗效和安全性研究
Yanjiao Du,Yan Li,Zhihui Duan et al.
Yanjiao Du et al.
What is known and objective: Many patients with acute ischemic stroke (AIS) develop early neurological deterioration (END), leading to disabilities or death. Thus, this study aimed to investigate the efficacy and safety o...
Randomized Controlled Trial
Journal of clinical pharmacy and therapeutics. 2022 Dec;47(12):2350-2359. DOI:10.1111/jcpt.13816 2022
A randomized, double-blind placebo-controlled phase I clinical study on safety and efficacy of the G-Rup® syrup (a mixture of ginger extract and honey) in symptomatic treatment of knee osteoarthritis [0.03%]
G-Rup®糖浆（姜提取物和蜂蜜的混合物）在膝骨关节炎对症治疗中的安全性和有效性随机双盲安慰剂对照一期临床研究
Fariba Afshar,Nafiseh Abdolahi,Gholamreza Amin et al.
Fariba Afshar et al.
What is known and objectives: Present study evaluated the safety profile and efficacy of G-Rup® syrup (100 mg/ml ginger extract plus 150 mg/ml honey) in symptomatic treatment of knee osteoarthritis (OA). ...
Management of biologics in pregnant, lactating patients with inflammatory bowel disease and the impact on neonatal vaccination: A systematic review of clinical practice guidelines and consensus statements [0.03%]
怀孕和哺乳期间炎症性肠病生物制剂的管理及对新生儿疫苗接种的影响：临床实践指南和共识声明的系统回顾
Ning Ding,Luqing Zhao,Lingfei Zhu et al.
Ning Ding et al.
What is known and objective: The management of biological agents during pregnancy poses challenges as maternal and infant safety must be addressed. This study aims to compare the recommendations of existing guidelines on ...
Wenxing Peng,Yifan Wang,Yunnan Zhang et al.
Wenxing Peng et al.
What is known and objective: Antiestrogen agents have been reported to enhance the anticoagulant activity of warfarin. The use of tamoxifen with warfarin has been contraindicated. However, warfarin in combination with tor...
The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial [0.03%]
口服皮质类固醇治疗Tietze综合征的疗效：实用随机对照试验
Hany Hasan Elsayed,Ihab Ali,Mohammed Abdel-Gayed et al.
Hany Hasan Elsayed et al.
What is known and objective: Tietze syndrome is a rare form of chest wall costochondritis with joint swelling which can cause significant chest pain and decline in ability of daily activities. There is no standardized tre...
Randomized Controlled Trial
Journal of clinical pharmacy and therapeutics. 2022 Dec;47(12):2279-2286. DOI:10.1111/jcpt.13810 2022
Effectiveness and safety of path-based analgesic regimens designed by clinical pharmacists based on the type of biliary and pancreatic surgery [0.03%]
基于临床药师根据胆道和胰腺手术类型设计的路径化镇痛方案的有效性和安全性研究
Han Xie,Xinmei Wang,Min Xue et al.
Han Xie et al.
What is known and objective: As the incidence of postoperative pain in patients with biliary and pancreatic diseases has gradually increased, how to control postoperative pain has received increasing research attention. B...