KLF13 overexpression protects sepsis-induced myocardial injury and LPS-induced inflammation and apoptosis [0.03%]
KLF13过表达可保护脓毒症诱导的心肌损伤以及LPS诱导的炎症和凋亡
Ni Zeng,Zaijin Jian,Wenxin Zhu et al.
Ni Zeng et al.
Sepsis remains a worldwide public health problem. This study aims to explore the role and mechanism of transcriptional factors (TFs) in sepsis-induced myocardial injury. Firstly, TF KLF13 was selected to explore its role in sepsis-induced m...
Silencing of RhoC induces macrophage M1 polarization to inhibit migration and invasion in colon cancer via regulating the PTEN/FOXO1 pathway [0.03%]
RhoC的沉默通过调节PTEN / FOXO1通路促进巨噬细胞M1极化，以抑制结肠癌中的转移和侵袭
Bin Yang,Lihua Wang,Zhiying Tian
Bin Yang
Ras homologue family member C (RhoC) is an oncogene in diverse types of human cancers, whereas its regulatory mechanisms involving macrophage polarization is rarely investigated. This study is designed to explore the regulatory role of RhoC...
Expression of autocrine motility factor receptor (AMFR) in human breast and lung invasive micropapillary carcinomas [0.03%]
人乳腺和肺侵袭性微乳头状癌中自分泌运动因子受体AMFR的表达
Jing Xu,Hongfei Ma,Qi Wang et al.
Jing Xu et al.
The aim of this study was to evaluate the clinicopathological significance of autocrine motility factor receptor (AMFR) expression in a variety of human invasive micropapillary carcinomas (IMPC). AMFR expression was compared in 111 samples ...
Cilostazol attenuates oxidative stress and apoptosis in the quadriceps muscle of the dystrophic mouse experimental model [0.03%]
环洛扎醇减轻杜氏肌营养不良小鼠模型股四头肌的氧化应激和凋亡
Túlio de Almeida Hermes,Rafael Dias Mâncio,Daniela Sayuri Mizobutti et al.
Túlio de Almeida Hermes et al.
Duchenne muscular dystrophy (DMD) is the most severe and frequent form of muscular dystrophy. The mdx mouse is one of the most widely used experimental models to understand aspects of the biology of dystrophic skeletal muscles and the mecha...
Protection of dystrophic muscle cells using Idebenone correlates with the interplay between calcium, oxidative stress and inflammation [0.03%]
使用艾地苯醌保护营养不良的肌肉细胞与钙、氧化应激和炎症之间的相互作用有关
Amanda Harduim Valduga,Daniela Sayuri Mizobuti,Fernanda Dos Santos Rapucci Moraes et al.
Amanda Harduim Valduga et al.
There is strong cross-talk between abnormal intracellular calcium concentration, high levels of reactive oxygen species (ROS) and an exacerbated inflammatory process in the dystrophic muscles of mdx mice, the experimental model of Duchenne ...
Long-term intake of aspartame-induced cardiovascular toxicity is reflected in altered histochemical parameters, evokes oxidative stress, and trigger P53-dependent apoptosis in a mouse model [0.03%]
长期摄入安赛蜜引起的心血管毒性反映在组织化学参数的改变中，可诱发氧化应激并触发小鼠模型中的P53依赖型凋亡
Hojat Anbara,Mehdi Kian,Gholam-Hossein Darya et al.
Hojat Anbara et al.
Aspartame (ASP) is probably the best known artificial sugar substitute that is used widely in food. Many experimental studies have reported the toxicity of long-term administration of ASP in various organ tissues. However, there is little e...
Skin fibrosis associated with keloid, scleroderma and Jorge Lobo's disease (lacaziosis): An immuno-histochemical study [0.03%]
与瘢痕增生、硬皮病和Jorge Lobo病（lacaziosis）相关的皮肤纤维化：一项免疫组化研究
Wagner Luiz Tafuri,Thaise Yumie Tomokane,Ana Maria Gonçalves Silva et al.
Wagner Luiz Tafuri et al.
Fibrosis is a common pathophysiological response of many tissues and organs subjected to chronic injury. Despite the diverse aetiology of keloid, lacaziosis and localized scleroderma, the process of fibrosis is present in the pathogenesis o...
Circular RNAs hsa_circ_0001438 and hsa_circ_0000417 are downregulated and upregulated, respectively, in hepatocellular carcinoma [0.03%]
肝癌中 Circular RNA hsa_circ_0001438 和 hsa_circ_0000417 分别下调和上调
Sachiko Imanishi,Shoko Nagata,Toshitsugu Fujita et al.
Sachiko Imanishi et al.
Hepatocellular carcinoma (HCC) is the most predominant type of liver cancer and is frequently fatal. Alpha-fetoprotein, alpha-fetoprotein-L3, and protein induced by vitamin K absence or antagonist-II are used as biomarkers to diagnose HCC. ...
Morphophysiological alterations in fruit-eating bats after oral exposure to deltamethrin [0.03%]
口服右旋胺丙烯后食果蝙蝠的形态生理变化
Jerusa Maria Oliveira,Suellen Silva Condessa,Ana Luiza Fonseca Destro et al.
Jerusa Maria Oliveira et al.
Deltamethrin (DTM) is a synthetic pyrethroid widely used in the cultivation and management of several crops due to its insecticidal action. Application to crops of pyrethroids such as DTM can result in the exposure of water and fruit consum...
Quantitative assessment of changes in skeletal muscle injury by computer-aided analysis based on two-dimensional ultrasonography combined with contrast-enhanced ultrasonography and estimated by a modified semi-quantitative scoring system: An experimental study in a contusion model [0.03%]
基于二维超声与对比增强超声的计算机辅助分析，定量评估肌肉挫伤模型中骨骼肌损伤变化：采用改良半定量评分系统估算的一项实验研究
Jiaqi Zhao,Hejing Huang,Qi Xu et al.
Jiaqi Zhao et al.
The aim of this study was to investigate the potential application of computer-aided analysis in the quantitative assessment of changes in skeletal muscle injury in the rabbit contusion model. Forty healthy rabbits were randomly divided int...