Increased accumulation of the advanced glycation endproduct Ne(carboxymethyl) lysine in the intramyocardial vasculature in patients with epicarditis [0.03%]
心包炎患者心肌内血管中的晚期糖基化终末产物羧甲基赖氨酸的积累增加
U Baylan,A Baidoshvili,S Simsek et al.
U Baylan et al.
Advanced glycation end-products (AGEs) are implicated in the pathogenesis of vascular disease. In previous studies we have found increased deposition of N(e)-(carboxymethyl)lysine (CML) in intramyocardial vasculature in the heart in acute m...
Circular RNA circVAPA modulates macrophage pyroptosis in sepsis-induced acute lung injury through targeting miR-212-3p/Sirt1/Nrf2/NLRP3 axis [0.03%]
环状RNA circVAPA通过靶向miR-212-3p/Sirt1/Nrf2/NLRP3轴调节脓毒症急性肺损伤中巨噬细胞焦亡
Yanjing Huang,Jinquan Lin,Zhiwei Wu et al.
Yanjing Huang et al.
Sepsis-induced acute lung injury (ALI) is an inflammatory condition involving the pyroptosis of macrophages. This study investigated the role of circular RNA hsa_circ_0006990 (circVAPA) in regulating macrophage pyroptosis in ALI and the und...
Anti-inflammatory and healing effect of the polysaccharidic extract of Opuntia ficus-indica cladodes in cutaneous excisional wounds in rats [0.03%]
仙人掌(Opuntia ficus-indica)多糖对大鼠切除皮肤创面的抗炎和修复作用
Beatriz Lima Adjafre,Iásly Costa Lima,Ana Paula Negreiros Nunes Alves et al.
Beatriz Lima Adjafre et al.
This study aimed to investigate the anti-inflammatory and wound healing effects of the polysaccharide extract from Opuntia ficus-indica cladodes (TPL-Ofi) using a rat cutaneous wound model. After anaesthesia, four 7-mm-diameter dorsal wound...
Exploring effect of M2 macrophages on experimental full-thickness wound healing in streptozotocin-induced diabetic rats [0.03%]
研究M2型巨噬细胞对链脲佐菌素诱导的糖尿病大鼠全层伤口愈合的影响
Parmis Khoshnoudi,Soroush Sabiza,Mohammad Khosravi et al.
Parmis Khoshnoudi et al.
Diabetes mellitus is one of the most prevalent medical conditions, in both humans and animals. People with diabetes mellitus often experience slower than normal wound healing, making it a serious health concern. This study investigates the ...
Notoginsenoside R1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via ERα/GSK-3β/β-catenin signalling pathway [0.03%]
诺高辛苷R1通过ERα/GSK-3β/β-catenin信号途径促进人骨髓间充质干细胞成骨分化
Wei Lu,Yuanxin Shi,Minglei Qian
Wei Lu
Human bone marrow mesenchymal stem cells (hBMSCs) are attractive therapeutic agents for bone tissue regeneration owing to their osteogenic differentiation potential. Notoginsenoside R1 (NGR1) is a novel phytoestrogen with diverse pharmacolo...
Interaction between mitochondrial homeostasis and barrier function in lipopolysaccharide-induced endothelial cell injury [0.03%]
脂多糖诱导的内皮细胞损伤中线粒体稳态和屏障功能之间的相互作用
Weiwei Zhu,Xiaojing Liu,Liqing Luo et al.
Weiwei Zhu et al.
This study aimed to investigate the effects of mitochondrial homeostasis on lipopolysaccharide (LPS)-induced endothelial cell barrier function and the mechanisms that underlie these effects. Cells were treated with LPS or oligomycin (mitoch...
Histomorphometric lung density evaluation of Immulina treatment using a murine influenza pneumonia model [0.03%]
Immudel治疗的肺密度组织几何形态学评价-用小鼠流感肺炎模型研究
Floyd D Wilson,Tahir M Mir,Mohammad K Ashfaq et al.
Floyd D Wilson et al.
Histomorphometric lung density measurements were used to evaluate the effects of Immulina on mouse pneumonia. Mice were intra-nasally exposed to H1N1 influenza virus at a dose of 5 × 104 PFU/50 μL/mouse. Lung density was measured using th...
Inhibition of inflammation and infiltration of M2 macrophages in NSCLC through the ATF3/CSF1 axis: Role of miR-27a-3p [0.03%]
ATF3/CSF1轴通过miR-27a-3p抑制非小细胞肺癌的炎症和M2型巨噬细胞浸润：作用机制研究
Bin Zhou,Yan Xu,Li Xu et al.
Bin Zhou et al.
Non-small cell lung cancer (NSCLC) imposes a significant economic burden on patients and society due to its low overall cure and survival rates. Tumour-associated macrophages (TAM) affect tumour development and may be a novel therapeutic ta...
Optimization of decellularization methods using human small intestinal submucosa for scaffold generation in regenerative medicine [0.03%]
用于再生医学中生成支架的人小肠粘膜下层脱细胞方法的优化
Shumei Mineta,Shunji Endo,Tomio Ueno
Shumei Mineta
Porcine small intestinal submucosa, despite its successful use as a scaffold in regenerative medicine, has innate biomechanical heterogeneity. In this study, we hypothesized that human small intestinal submucosa could be a viable alternativ...