Optogenetic control of cancer cell survival in ChR2-transfected HeLa cells [0.03%]
光遗传学在ChR2转染的HeLa细胞中对癌细胞存活的控制
Claudio Córdova,Carlo Lozano,Belén Rodríguez et al.
Claudio Córdova et al.
Optogenetics is a molecular biological technique involving transfection of cells with photosensitive proteins and the subsequent study of their biological effects. The aim of this study was to evaluate the effect of blue light on the surviv...
Immunohistochemical and immunofluorescence expression profile of lymphatic endothelial cell markers in oral cancer [0.03%]
口腔癌中淋巴内皮细胞标记物的免疫组织化学和免疫荧光表达谱分析
Kullasit Chutipongpisit,V Praveen Parachuru,Lara T Friedlander et al.
Kullasit Chutipongpisit et al.
Lymphangiogenesis makes an important contribution to the tumour microenvironment (TME), but little is known about this in oral squamous cell carcinoma (OSCC). Archival formalin-fixed paraffin-embedded specimens (28 OSCC, 10 inflamed and 6 n...
Correlation between aryl hydrocarbon receptor and IL-17+ and Foxp3+ T-cell infiltration in bladder cancer [0.03%]
芳香烃受体与膀胱癌中IL-17和Foxp3阳性T细胞浸润的相关性研究
Soheila Fattahi,Monireh Karimi,Mahdi Ghatreh-Samani et al.
Soheila Fattahi et al.
Bladder cancer (BC) is one of the most prevalent cancers around the world and, if not treated well, has high morbidity and mortality. Many studies have indicated that there may be various roles for the aryl hydrocarbon receptor (AHR) in the...
The intensity of the foreign body response to polyether-polyurethane implant in diabetic mice is strain-dependent [0.03%]
糖尿病小鼠对聚醚聚氨酯植入物的异物反应强度取决于品系
Simone A de Almeida,Laura A A Orellano,Luciana X Pereira et al.
Simone A de Almeida et al.
A number of genetic factors have been linked to the development of diabetes, a condition that often requires implantable devices such as glucose sensors. In normoglycaemic individuals, this procedure induces a foreign body reaction (FBR) th...
Soy diet induces intestinal inflammation in adult Zebrafish: Role of OTX and P53 family [0.03%]
大豆饮食诱导成年斑马鱼肠道炎症：OTX和P53家族的作用
Giovanni Micheloni,Marta Carnovali,Giorgia Millefanti et al.
Giovanni Micheloni et al.
Inflammatory bowel diseases (IBDs) are a group of inflammatory conditions of the colon and small intestine, including Crohn's disease and ulcerative colitis. Since Danio rerio is a promising animal model to study gut function, we developed ...
miR-381-3p attenuates doxorubicin resistance in human anaplastic thyroid carcinoma via targeting homeobox A9 [0.03%]
通过靶向同源盒A9，miR-381-3p减弱人类甲状腺癌的多柔比星耐药性
Yan Zhang,Ke Li,Weili Wang et al.
Yan Zhang et al.
Abnormal microRNA (miR) expression has frequently been reported to be implicated in cancer-related drug resistance. Herein, we planned to investigate whether miR-381-3p contributes to doxorubicin (DOX) resistance in anaplastic thyroid carci...
miR-942-5p prevents sepsis-induced acute lung injury via targeting TRIM37 [0.03%]
通过靶向TRIM37 miR-942-5p预防脓毒症诱导的急性肺损伤
Qiang Lu,Dinggao Zhang,Hui Liu et al.
Qiang Lu et al.
MicroRNAs (miRNAs) have been demonstrated to play pivotal roles in the pathogenesis of sepsis-induced acute lung injury (ALI). In this work, we aimed to clarify the potential role and the underlying mechanism of miR-942-5p in a lipopolysacc...
Evidence for age-related contributions of DNA damage and epigenetics in brain tumorigenesis [0.03%]
DNA损伤和表观遗传学在脑肿瘤发生中年龄相关作用的证据
Adrian Tira,Lela Buckingham
Adrian Tira
Glioblastoma (GBM) is a highly malignant primary brain tumour displaying rapid cell proliferation and infiltration. GBM primarily occurs at older age; however, younger populations have also been affected. In GBM and other cancers, genetic a...
miR-378-3p alleviates contusion spinal cord injury by negatively regulating ATG12 [0.03%]
miR-378-3p通过负向调节ATG12来缓解脊髓挫伤损伤
Haocong Zhang,Hailong Yu,Huifeng Yang et al.
Haocong Zhang et al.
MicroRNAs (miRNAs or miRs) serve essential roles in the pathogenic process of spinal cord injury (SCI). The present study investigated the role of miR-378-3p and autophagy-related 12 (ATG12) in SCI. RT-qPCR was used to detect the mRNA expre...