Worming out defence strategies: mechanisms of immunity through the lens of genetic screens in C. elegans [0.03%]
透过基因筛选看C. elegans的防御策略：免疫机制
Manish Grover,Domenica Ippolito,Michalis Barkoulas
Manish Grover
Since Sydney Brenner's foundational work in 1974, Caenorhabditis elegans has served as an impactful model for biological discovery primarily driven by genetic approaches, including mutagenesis-based screens and RNAi-based functional genomic...
Elevated rates of nondisjunction in a selfish X chromosome that causes female meiotic drive in Drosophila testacea [0.03%]
驱动果蝇睾腮亚种雌性配子的自私X染色体具有较高的非整倍体变异率
Michael W Clark,Steve J Perlman
Michael W Clark
Meiotic drivers are selfish genetic elements that manipulate the process of meiosis to increase their transmission, circumventing Mendel's Law of equal segregation. Because meiosis fundamentally differs between the sexes, meiotic drivers us...
Minimum marker densities for accurate genomic predictions and heritability estimates in three major North American and European spruce species [0.03%]
北美和欧洲三种主要云杉物种进行准确的基因组预测和遗传参数估计所需的最小标记密度
André Soro,Patrick Lenz,Jean Beaulieu et al.
André Soro et al.
Genomic selection (GS) is being increasingly used in tree breeding with the aim to accelerate genetic gains by shortening the long breeding cycles. However, high genotyping costs remain a challenge. This study aimed to determine the optimal...
Genome assembly of Astatotilapia latifasciata uncovers B chromosome-linked chromatin reorganization [0.03%]
Astatotilapia latifasciata基因组组装揭示了B染色体连接的染色质重构
Maryam Jehangir,Syed Farhan Ahmad,Jordana Inácio Nascimento Oliveira et al.
Maryam Jehangir et al.
B chromosomes (Bs) are supernumerary genomic elements found in many eukaryotes, yet their full sequence composition, functional potential, and regulatory impact on the host genome remain unclear. Here, we present a chromosome-level genome a...
High selfing rate and inbreeding depression correlate with past range expansion in an endangered African timber species Pericopsis elata [0.03%]
自交率高和近交衰退与濒危非洲名贵木材树种Pericopsis elata的过去扩散相关性研究
Bloude L B Toumba-Paka,Gaël U D Bouka,Surabhi Ranavat et al.
Bloude L B Toumba-Paka et al.
Self-fertilization and inbreeding depression (δ) are expected to co-evolve, particularly during range expansion, yet few studies have examined this dynamic in tropical trees, which could be relevant for their conservation. We investigated ...
Alex Aylward,Daniel J Fairbanks,Maria Kiladi et al.
Alex Aylward et al.
Genetics and eugenics co-evolved at the beginning of the twentieth century and remained associated through the 1940s and beyond. Early geneticists were far from unanimous in their views on eugenics; some avidly supported the movement, where...
Sara Goodacre
Sara Goodacre
Editorial
Heredity. 2026 Apr 20. DOI:10.1038/s41437-026-00840-x 2026
Mink by mink: stitching together signatures of subspecies adaptation through a pangenome of threatened mustelids [0.03%]
Mustela中的基因组拼接：通过濒危Mustelidae的泛基因组拼凑亚种适应的签名
Aishatu Affini,Hailey Baranowski,Scott Forbes et al.
Aishatu Affini et al.
Subspecies represent evolutionarily distinct lineages that preserve patterns of adaptive diversity and ecological specialization within species. Genomic tools can assist with subspecies delineation, and provide support for classifications b...
Adaptive value of marginal populations: integrating selective signals, neutral processes and temporal scales [0.03%]
边缘群体的适应价值：整合选择信号、中性过程和时间尺度
Carlos Lara-Romero,José M Iriondo,Alfredo García-Fernández et al.
Carlos Lara-Romero et al.
The importance of populations inhabiting ecologically marginal areas has been extensively debated and shown to depend largely on their adaptive value. These populations may harbour unique genetic combinations essential for long-term resilie...
Diversification across the Australian Monsoonal Tropics: Comparing phylogeographic and demographic patterns within and between species of Cryptoblepharus skinks [0.03%]
横跨澳大利亚季风热带的物种分化：比较Cryptoblepharus蜥蜴属内和属间的谱系地理和数量遗传模式
Sofía I Hayden Bofill,Sally Potter,Ana C Afonso Silva et al.
Sofía I Hayden Bofill et al.
Organisms vary in their ability to cope with environmental perturbations, and even closely related species can differ in their resilience to climate change. For example, generalists may be better at accommodating environmental change than s...