Identification of Iron Overload-Associated Biomarkers in the Synovium of Haemophilic Arthropathy [0.03%]
血友病性关节炎铁过载相关滑膜组织生物标志物的识别
Yi Hu,Dasheng Luo,Defu Yu
Yi Hu
Background: Haemophilic arthropathy (HA) is a common complication of haemophilia, characterized by progressive joint degeneration due to recurrent bleeding. Iron overload from erythrocyte lysis is thought to play a key ro...
Health-Related Quality of Life in Adult Patients With von Willebrand Disease From Germany: Results of the WIL-QoL Study [0.03%]
德国成人血管性血友病患者的生命质量：WIL-QoL研究结果
Sylvia von Mackensen,Carolin Moorthi,Ronald Fischer et al.
Sylvia von Mackensen et al.
Introduction: Assessment of health-related quality of life (HRQoL) is relatively new in von Willebrand disease (VWD). So far, generic questionnaires have mainly been used for HRQoL assessment in VWD. ...
Clinical Course of Residual Flexion Contracture After Total Knee Arthroplasty in Patients With Haemophilic Arthropathy [0.03%]
血友病性关节病全膝关节置换术后残留屈曲挛缩的临床转归
Seyed Mohammad Javad Mortazavi,Babak Haghpanah,Mohammadhasan Kaseb et al.
Seyed Mohammad Javad Mortazavi et al.
Aim: This study aims to evaluate the natural course and resolution of flexion contracture following total knee arthroplasty (TKA) in individuals with haemophilic arthropathy. ...
Real-World Data on Quality of Life in Relation to the Type of Prophylaxis in Polish Children With Haemophilia A-A Nationwide Study [0.03%]
波兰血友病儿童的预防类型与生活质量的全国性研究
Klaudia Paczóska,Wanda Badowska,Halina Bobrowska et al.
Klaudia Paczóska et al.
Background: Modern prophylaxis in haemophilia aims not only to prevent bleeding but also to ensure a quality of life (QoL) comparable to healthy peers. Real-world data on health-related QoL (HRQoL) in children receiving p...
In Silico Assessment of Limited Blood Sampling Strategies for Individualised Pharmacokinetic-guided Dosing of Efanesoctocog Alfa in Haemophilia A Patients [0.03%]
虚拟评估艾尼昔阳托科格阿尔法在甲型血友病患者个体化药动学指导给药的限制性取样策略
Jelien den Hollander,Marjon H Cnossen,Ron A A Mathôt
Jelien den Hollander
Introduction: Efanesoctocog alfa is a novel factor VIII (FVIII) concentrate with a unique molecular design that enables Von Willebrand Factor-independent clearance in patients with haemophilia A. Limited sampling strategi...
Family-Borne Financial Costs of Managing Paediatric Haemophilia in a Government Facility in North India [0.03%]
北印度政府医疗设施中儿童血友病的家庭经济负担
Nita Radhakrishnan,Archit Pandharipande,Ritu Gupta et al.
Nita Radhakrishnan et al.
Background: In India, persons with haemophilia (PWH) are entitled to free diagnostic services, clotting-factor concentrates and physiotherapy. However, families often continue to experience substantial financial hardships...
Impact of Fidanacogene Elaparvovec Gene Therapy on Joint Health in Adults With Haemophilia B: Results From a Phase 3 Study [0.03%]
因子介导基因疗法对乙型血友病成人患者关节健康的影响：一项3期研究的结果
Davide Matino,Laurent Frenzel,Ali Bulent Antmen et al.
Davide Matino et al.
Characterising Glanzmann Thrombasthenia in the United States: Real-World Data From the EPIC Cosmos Dataset [0.03%]
美国葡萄糖耐量低下的特征：来自EPIC Cosmos数据集的现实世界数据
Divyaswathi Citla-Sridhar,Daniel Liu
Divyaswathi Citla-Sridhar
Background: Glanzmann Thrombasthenia (GT) is a rare autosomal recessive bleeding disorder characterised by defective platelet aggregation due to abnormalities in the glycoprotein IIb/IIIa complex. With a lack of large rea...
Clinical, Obstetric-Gynaecological and HRQoL Data of Female VWD Patients in the WIL-QoL Study [0.03%]
WIL-QoL研究中的女性血管性血友病患者的临床、妇产科和HRQoL数据
Susan Halimeh,Cornelia Wermes,Carolin Moorthi et al.
Susan Halimeh et al.
Introduction: Von Willebrand disease (VWD) is one of the most common hereditary disorders of primary haemostasis. Females with VWD often report heavy menstrual bleeding (HMB) that can significantly impact health-related q...
Coagulation Factor Consumption and Medium- to Long-Term Outcomes of Achilles Tendon Lengthening With and Without External Fixation in Haemophilia [0.03%]
不同剂量凝血因子下外固定与单纯跟腱延长治疗血友病患者的中长期疗效分析
Ze Chen,Guiyong Jiang,Yaowen Xu et al.
Ze Chen et al.
Introduction: Achilles tendon lengthening combined with external fixation (EF) has shown promising outcomes in managing haemophilia-related Achilles tendon contracture. ...