Assay of Efanesoctocog Alfa in 200 Centres: Data Form Collaborative NEQAS BC (United Kingdom) and ECAT (Netherlands) Exercise Autumn 2024 [0.03%]
2024年秋季英国NEQAS BC和荷兰ECAT协同评估Efanesoctocog Alfa的200个中心检测结果分析
Christopher Reilly-Stitt,Piet Meijer,Ian Jennings et al.
Christopher Reilly-Stitt et al.
Background: Efanesoctocog alfa (EFA) is an ultra-long half-life FVIII product. However, measuring the level of EFA using standard one stage (OSA) and Chromogenic assays (CA) is affected by both underestimation and overest...
Dental Neglect by Individuals With Haemophilia: Clinical Challenges and Solutions [0.03%]
血友病患者忽视口腔健康：临床挑战与解决方案
Mathangi Kumar,Sulochana Badagabettu,Pavitra Ds et al.
Mathangi Kumar et al.
Background: Haemophilia is a chronic disorder and dental health forms an integral part of overall health in individuals with haemophilia. Objective: ...
Patient and Caregiver Preferences for Long-Term Prophylactic Treatment of Bleeds in Haemophilia: A Discrete-Choice Experiment [0.03%]
血友病患者和护理人员对长期预防性治疗偏好的研究：基于选择试验的一项研究
Hui Lu,Travis Gould,Carmine Colavecchia et al.
Hui Lu et al.
Introduction: The expansion of haemophilia treatment to include non-factor prophylaxis provides new options with various benefits, risks, administration modes, and device types, necessitating trade-offs in decision-making...
Haemophilic Elbow Arthropathy: Mechanisms, Management and Future Perspectives [0.03%]
血友病性肘关节病变：机制、治疗和未来展望
Sébastien Lobet,Olivier Barbier,Catherine Lambert et al.
Sébastien Lobet et al.
Introduction: Haemophilic elbow arthropathy (HEA) causes pain, limits mobility, and impairs upper limb function, often unrecognised until irreversible damage has occurred. ...
Distressing Bleeding Symptoms in Interviews of Patients With Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder [0.03%]
高关节活动度型Ehlers-Danlos综合征和关节活动度过大型多谱系障碍患者的出血症状调查结果令人担忧
Rohith Jesudas,Sarah A Mathena,Kenneth L Zhang et al.
Rohith Jesudas et al.
Introduction: Hypermobile Ehlers-Danlos Syndrome (hEDS) and hypermobility spectrum disorder (HSD) are associated with symptoms in many organ, but those related to haemostasis are not fully characterized. ...
Monitoring of Nonacog Beta Pegol: One-Stage Clotting Assay With Kaolin Reagent as a Practical Alternative to Chromogenic Methods [0.03%]
非俄克 pegol 的监测试验：使用明胶电解质凝固法 kaolin 试剂作为色谱法试验的替代方法
Marie Prudková,Petr Smejkal,Dagmar Chytrá et al.
Marie Prudková et al.
Introduction: Accurate monitoring of nonacog beta pegol (N9-GP) is essential to ensure appropriate treatment and to avoid under- or overdosing, which may result in clinical complications. The product's extended half-life,...
Health-Related Quality of Life in Egyptian Children With Haemophilia A and Chronic Arthropathy With the Era of Emicizumab Therapy: A Single-Centre Cohort Study [0.03%]
埃及A型血友病儿童相关关节病的医疗卫生关联生活质量：emicizumab治疗时代的单中心队列研究
Gehan Lotfy Abdel Hakeem Khalifa,Rawhya Rabei Abdel Tawab,Mohamed Ahmed Bahaa et al.
Gehan Lotfy Abdel Hakeem Khalifa et al.
Aim: To assess the health-related quality of life (HRQOL) in children with haemophilia A and arthropathy before and after emicizumab prophylaxis using the Canadian Haemophilia Outcomes-Kids' Life Assessment Tool questionn...
Total Knee Arthroplasty in Severe Hemophilic Arthropathy With Stiff Knees(Preoperative Flexion Range of Motion ≤40°): Functional Outcomes and Long-Term Survivorship [0.03%]
膝关节僵硬（术前屈曲活动度≤40°）的血友病性骨关节病全膝关节置换的功能预后和长期生存率
Seyed Mohammad Javad Mortazavi,Davood Dehghani Ashkzari,Hani Azizikia et al.
Seyed Mohammad Javad Mortazavi et al.
Aim: This study aimed to evaluate the clinical and radiographic outcomes of total knee arthroplasty (TKA) in patients with haemophilia A and severely stiff knees (preoperative flexion range of motion ≤40°) with a focus ...
Identification of Iron Overload-Associated Biomarkers in the Synovium of Haemophilic Arthropathy [0.03%]
血友病性关节炎铁过载相关滑膜组织生物标志物的识别
Yi Hu,Dasheng Luo,Defu Yu
Yi Hu
Background: Haemophilic arthropathy (HA) is a common complication of haemophilia, characterized by progressive joint degeneration due to recurrent bleeding. Iron overload from erythrocyte lysis is thought to play a key ro...
Health-Related Quality of Life in Adult Patients With von Willebrand Disease From Germany: Results of the WIL-QoL Study [0.03%]
德国成人血管性血友病患者的生命质量：WIL-QoL研究结果
Sylvia von Mackensen,Carolin Moorthi,Ronald Fischer et al.
Sylvia von Mackensen et al.
Introduction: Assessment of health-related quality of life (HRQoL) is relatively new in von Willebrand disease (VWD). So far, generic questionnaires have mainly been used for HRQoL assessment in VWD. ...