Predicting Recovery After Joint Bleeding in Persons With Bleeding Disorders [0.03%]
预测出血性疾病患者的关节出血恢复情况
Gijs Aertssen,Lize F D van Vulpen,Wouter Foppen et al.
Gijs Aertssen et al.
Introduction: Joint bleeds are burdensome and recovery differs from bleed to bleed. Identifying predictors of recovery could enable personalized treatment and monitoring; aiming to prevent long-term joint deterioration, a...
Integrating Primary Care Screening Into a Haemophilia Treatment Centre Comprehensive Care Model: Early Outcomes From a Nurse Practitioner-Led Pilot Programme [0.03%]
基于护师的基层医疗筛查整合至血友病治疗中心综合护理模式的试点项目初步结果
Joseph Stanco,Suchitra Acharya
Joseph Stanco
Implementing Shared Decision-Making in Haemophilia Care: Best Practice Recommendations From a Western European Multi-Stakeholder Delphi Process [0.03%]
血友病护理中实施共同决策：来自西方欧洲多方利害关系人德尔菲过程的最佳实践建议
Donna Coffin,Robert Klamroth,Miguel Crato et al.
Donna Coffin et al.
Introduction: Shared decision-making (SDM) is a collaborative process in which people with haemophilia (PWH) and healthcare professionals (HCPs) make treatment decisions informed by the best available evidence and aligned...
Maísa Veríssimo,Tatiana Kuhn,Janaina Ricciardi et al.
Maísa Veríssimo et al.
Background: Advances in haemophilia treatment have enabled safe exercise practice as recommended by disease management guidelines, yet there is no gold-standard protocol for optimal dose. Emerging therapies could influenc...
Pathogenic Variant VWF-Cys2750Phe in CK Domain Caused Type 2A VWD by Impairing VWF Multimerization and Secretion [0.03%]
VWF-半胱天冬氨酸2750苯丙氨酸致血管性血友病的发病机制研究：干扰VWF多聚化和分泌导致2A型血管性血友病变异型病症生成
Duanyang Wang,Peiqi Cao,Lei Wang et al.
Duanyang Wang et al.
Central Nervous System Bleeding in Children With Haemophilia in Limited Resource [0.03%]
低收入国家血友病儿童中枢神经系统出血的临床特征分析
Patcharee Komvilaisak,Sudarat Sirichaipornsak,Paiporn Sripraya et al.
Patcharee Komvilaisak et al.
Introduction: Central nervous system (CNS) bleeding in children with haemophilia is a life-threatening complication that may cause severe neurological sequelae or death. In resource-limited settings, where prophylaxis is ...
TNF‑α Gene Polymorphisms as Determinants of Alloantibody Emergence in Hemophilia: A Systematic Review and Meta-Analysis [0.03%]
肿瘤坏死因子(TNF)-α基因多态性与血友病患者自身抗体产生相关的系统评价和 meta 分析
Alessandra Faustino da Conceição Bezerra,Natã Abner Andrade Carito de Sousa,Suely Meireles Rezende et al.
Alessandra Faustino da Conceição Bezerra et al.
Introduction: Inhibitor development remains one of the most serious complications of replacement therapy in patients with hemophilia. Tumour necrosis factor-alpha (TNF-α) is a key pro-inflammatory cytokine, and its genet...
Beyond the Surface: Bone Marrow Oedema as a Hidden Marker of Pain in Haemophilic Ankles [0.03%]
浅表之下的隐性疼痛标志：血友病踝关节骨髓水肿病变
Sébastien Lobet,Sylvain Guillaume,Valérie-Anne Chantrain et al.
Sébastien Lobet et al.
Introduction: Magnetic resonance imaging (MRI) is the gold standard for assessing haemophilic arthropathy using the IPSG scale. However, MRI-detected abnormalities often correlate poorly with pain, suggesting that structu...
Investigation of the Suitability of the ROTEM Assay to Measure Coagulation Potential in Blood From Patients on Concizumab Prophylaxis [0.03%]
评估ROTEM检测方法在康西珠单抗预防治疗患者血液中凝血潜能的适用性研究
Hermann Eichler,Nora V Butta,Anne Riddell et al.
Hermann Eichler et al.
Background: Rotational thromboelastometry (ROTEM) aims to measure the coagulation potential in whole blood. Concizumab, an anti-tissue factor pathway inhibitor (TFPI) antibody for prophylaxis in haemophilia, enhances tiss...
Alexander Schmidt,Marius Brühl,Pia Möllers et al.
Alexander Schmidt et al.
Introduction: Sufficient sleep is essential for maintaining both physical and mental health, yet data on sleep health among persons with haemophilia (PwH) remain limited. ...