Endothelial activation and stress index score as a predictor of transplant-associated thrombotic microangiopathy in patients with sickle cell disease [0.03%]
内皮激活和应激指数评分作为预测血红蛋白SC病患者移植相关性血栓性微血管病的指标
Reethu Krishnan,Hari Sankaran,David Jacobsohn et al.
Reethu Krishnan et al.
In-depth analysis of osmotic gradient ektacytometry parameters across different genotypes in hereditary spherocytosis [0.03%]
遗传性球形红细胞增多症不同基因型的渗透梯度ektacytometry参数分析
Jonathan R A de Wilde,Geoffrey Z L Kuppens,Maryse E Boesveld et al.
Jonathan R A de Wilde et al.
Hereditary spherocytosis (HS) is a hereditary haemolytic anaemia, caused by pathogenic variants in genes encoding red blood cell membrane proteins. Osmotic gradient ektacytometry evaluates red cell deformability and hydration and is increas...
Patient-reported health-related quality of life in previously untreated chronic lymphocytic leukaemia: Results from the randomised phase 3 FLAIR trial comparing ibrutinib-rituximab versus fludarabine-cyclophosphamide-rituximab [0.03%]
初治慢性淋巴细胞白血病患者相关生活质量:伊布替尼联合利妥昔单抗对比氟达拉滨、环磷酰胺、利妥昔单抗(FLAIR研究)的随机III期临床试验结果分析
David J Allsup,David A Cairns,E Faye Samy et al.
David J Allsup et al.
Front-Line therapy in CLL: Assessment of Ibrutinib-containing Regimens (FLAIR) demonstrated improved progression-free survival for ibrutinib and rituximab (IR) compared with fludarabine, cyclophosphamide and rituximab (FCR) in previously un...
Hepatitis C virus and hepatitis B virus in indolent lymphomas: Prospective data from the international observational NF10 study [0.03%]
国际观察性NF10研究中惰性淋巴瘤患者的丙型肝炎病毒感染及乙肝病毒表面抗原携带状况:一项前瞻性研究结果
Luca Arcaini,Michele Merli,Sara Rattotti et al.
Luca Arcaini et al.
Cyclin D1 immunostaining as a diagnostic surrogate for the t(11;14) translocation in AL amyloidosis [0.03%]
cyclin D1免疫组化检测作为AL淀粉样变性t(11;14)易位诊断替代标记物的研究
Thomas George,Andrew Staron,Eric J Burks et al.
Thomas George et al.
Exploiting ALK inhibition in anaplastic large cell lymphoma: Biological rationale and therapeutic integration [0.03%]
在间变性大细胞淋巴瘤中利用ALK抑制:生物学原理和治疗整合
Santino Caserta,Enrica Antonia Martino,Mamdouh Skafi et al.
Santino Caserta et al.
Mature T-cell lymphomas comprise a heterogeneous group of aggressive non-Hodgkin lymphomas with limited therapeutic options in the relapsed or refractory setting. Among them, anaplastic lymphoma kinase (ALK)-positive anaplastic large cell l...
Chronic active Epstein-Barr virus disease in children: Clinical outcomes and prognostic risk factors from a 149-patient cohort [0.03%]
儿童慢性活动性EB病毒病的临床特征、预后因素及治疗效果——基于149例患者的队列研究
Qing Zhang,Yun-Ze Zhao,Dong Wang et al.
Qing Zhang et al.
Chronic active Epstein-Barr virus disease (CAEBV), an Epstein-Barr virus (EBV)+ T/Natural Killer (NK)-cell lymphoproliferative disorder, remains critically undefined in treatment and prognostic stratification due to its rarity. We analysed ...
Serum free light chain concentration and ratio-based criterion for myeloma-defining event, in its current version, is untenable [0.03%]
现行的游离轻链浓度和比例界定多发性骨髓瘤诊断标准不合理
Gurmukh Singh
Gurmukh Singh
Clinical decision-making based on myeloma-defining event criteria using thresholds for involved serum free light chain level of 10 mg/dL and ratio of involved to uninvolved light chain of >100 is a poor indicator for the risk of progression...
MRD-negative conversion with daratumumab monotherapy in newly diagnosed multiple myeloma patients in ≥VGPR/MRD-positive after first-line therapy: Final analysis of the open-label, single-arm multicentric phase 2 trial DART4MM [0.03%]
达雷妥尤单抗单药治疗新诊断多发性骨髓瘤患者(一线治疗后达到≥VGPR但MRD阳性)使MRD转阴:DART4MM开放标签、单臂、多中心Ⅱ期试验的最终分析
Alessandro Gozzetti,Paola Pacelli,Federico Caroni et al.
Alessandro Gozzetti et al.
Daratumumab is approved for front-line and relapsed myeloma therapy. Here, we evaluated daratumumab in multiple myeloma patients already in ≥very good partial response but minimal residual disease (MRD) positive by next-generation flow aft...
Evaluation of surgical evacuation of the uterus for abortion and management of miscarriage in patients with sickle cell disease: A multicentre UK study [0.03%]
评估手术清除子宫作为镰状细胞疾病患者的堕胎和流产管理方法:英国多中心研究
Sonia Wolf,Natasha Lewis,Funmi Oyesanya et al.
Sonia Wolf et al.