Guido Nador,Rohit Vijjhalwar,Muhammad Kassim Javaid et al.
Guido Nador et al.
Multiple myeloma (MM) is a haematological malignancy characterised by clonal plasma cell accumulation in the bone marrow, frequently resulting in myeloma bone disease. Disruption of bone homeostasis, driven by increased osteoclastic resorpt...
HAT-PCR is non-inferior to NGS when quantifying measurable residual disease for myeloma [0.03%]
当量化多发性骨髓瘤的可测量残留病时，帽解链扩增聚合酶链反应不劣于下一代测序技术
Elizabeth Hughes,Piers Blombery,Sushmitha Kannan et al.
Elizabeth Hughes et al.
Immunological features of acquired pure red cell aplasia: Specific human leucocyte antigen alleles, signal transducer and activator of transcription 3 mutations and a unique T-cell receptor beta motif [0.03%]
获得性纯红细胞再生障碍的免疫学特征：特定的人类白细胞抗原等位基因、信号转导子和转录激活蛋白3突变及独特的T细胞受体β基序
Naruaki Yamashita,Toru Kawakami,Shuji Matsuzawa et al.
Naruaki Yamashita et al.
T-cell abnormalities have been implicated in the pathogenesis of acquired pure red cell aplasia (PRCA), particularly in its major subtypes such as idiopathic PRCA, thymoma-associated PRCA and large granular lymphocytic leukaemia (LGLL)-asso...
Federico Spataro,Vanessa Desantis,Antonio Giovanni Solimando
Federico Spataro
Pure red cell aplasia (PRCA) is increasingly recognised as a T-cell-mediated bone marrow failure syndrome, yet its immunogenetic drivers remain poorly defined. In their paper, Yamashita et al. integrate human leucocyte antigen (HLA) typing,...
Robert Wynn,Rick Admiraal,Caroline Lindemans
Robert Wynn
Madkhali et al. Dose de-escalation of alemtuzumab in matched unrelated donor haematopoietic stem cell transplantation. Br J Haematol 2026 (Online ahead of print). doi: 10.1111/bjh.70318. ...
Neurofilament as a biomarker of neurodegeneration in childhood Langerhans cell histiocytosis: A feasibility study on 273 patients [0.03%]
神经丝作为儿童朗格汉斯细胞组织细胞增生症神经变性生物标志物的可行性研究：273例患者分析
Solenne Le Louet,Camille Brunaud,Mohamed Barkaoui et al.
Solenne Le Louet et al.
Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), often leading to progressive neurological decline. We evaluated the usefulness of using plasma and cerebrospinal fluid neurofilament light chain (p- and...
Short-course blood transfusion therapy with hydroxyurea, a functional strategy in the management of stroke in children with sickle cell disease [0.03%]
短程输血联合羟基脲治疗镰状细胞病儿童脑卒中的疗效分析
Edamisan Temiye,Adeseye Akinsete,Adetokunbo Joacquim et al.
Edamisan Temiye et al.
Cerebrovascular accidents are serious complications of sickle cell disease (SCD). Children with abnormal transcranial Doppler (TCD) readings are at higher risk for stroke, and those with prior strokes have increased risk of recurrence. Chro...
Trends in survival outcomes after allogeneic transplantation for MDS and MDS/MPN in a real-world experience: A 25-year nationwide study [0.03%]
真实世界异基因移植治疗MDS和MDS/MPN生存状态的长期趋势：一项全国性研究回顾（1993-2018）
Hidehiro Itonaga,Yasushi Miyazaki,Noriaki Tachi et al.
Hidehiro Itonaga et al.
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) offers a curative potential for myelodysplastic syndrome (MDS) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN). We examined survival trends using a nationwide databas...
Clinical features and maternal-fetal outcome of pregnancy with aplastic anaemia: A single-centre retrospective study [0.03%]
单纯性再生障碍性贫血妊娠的临床特点及母婴结局：单中心回顾研究
Xiaoxia Wu,Zhen Yang,Xinhui Zhang et al.
Xiaoxia Wu et al.
Pregnancy complicated by aplastic anaemia (AA) is rare but high risk, with historically poor maternal-fetal outcomes. Contemporary multidisciplinary management may improve prognosis, underscoring the need to clarify current outcomes and ris...
Differential complement activation by alloantibodies in sickle cell hyperhaemolysis syndrome may influence disease course [0.03%]
异常的补体活化在镰状细胞病溶血综合征中可能影响疾病进程
Mamie M Thant,Jahnavi Gollamudi,Stefanie W Benoit et al.
Mamie M Thant et al.