Stomatocytosis with large platelets: An important clue to sitosterolaemia [0.03%]
stomatocyte红细胞增多症伴大型血小板：植物甾醇血症的重要线索
Ren Xiang,Ge Meili
Ren Xiang
Genetic characterization of AML defined by differentiation shows a high frequency of DDX41 mutations [0.03%]
基于分化功能表型定义的急性髓系白血病遗传特征分析发现DDX41高频突变
Sandra Huber,Christoph Kornauth,Stephan Hutter et al.
Sandra Huber et al.
Benefit of selinexor dose reduction on outcomes with selinexor, bortezomib and dexamethasone in patients with lenalidomide-refractory multiple myeloma: Subgroup analysis of the BOSTON trial [0.03%]
塞利尼索剂量减少对来那度胺难治多发性骨髓瘤患者赛利尼索，硼替佐米和地塞米松疗效的影响：BOSTON试验的亚组分析
Sosana Delimpasi,Ivan Špička,Jason P Butler et al.
Sosana Delimpasi et al.
A subgroup analysis of efficacy, safety and QOL in patients who received selinexor in combination with bortezomib and dexamethasone (SVd) with and without selinexor dose reduction and who had lenalidomide-refractory disease in the phase 3 B...
Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country [0.03%]
基于西方国家700例患者的Castleman病谱系研究
Eric Oksenhendler,Marion Malphettes,Véronique Meignin et al.
Eric Oksenhendler et al.
Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time. Using the French national registry for CDs, we revisited the full spectrum of these diseases to update our ...
Contrasting impacts of pretransplant cytoreduction and post-transplant maintenance on outcomes of allogeneic haematopoietic stem cell transplantation in myelodysplastic syndromes: Real-world multicentre evidence [0.03%]
预移植细胞减少与异基因造血干细胞移植后维持治疗对骨髓衰竭性疾病疗效影响的多中心真实世界证据研究
Yilin Chen,Xiaotong Zhang,Na Shen et al.
Yilin Chen et al.
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) remains the only curative therapy for patients with high-risk myelodysplastic syndrome (MDS). However, the optimal timing and value of pretransplant cytoreduction and post-tran...
Treosulfan-fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study [0.03%]
用于重症联合免疫缺陷婴儿的三硫酸盐-氟达拉滨预处理：英国儿科三硫酸盐研究的扩展研究
Su Han Lum,Sinéad Greener,Irum Latif Memon et al.
Su Han Lum et al.
Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks ...
BRAF inhibitor plus rituximab in classical hairy cell leukaemia: A retrospective multicentre real-life study [0.03%]
一项关于经典毛细胞白血病的贝拉法尼布抑制剂联合利妥昔单抗的多中心回顾性真实世界研究
Urbain Tauveron-Jalenques,Luca Inchiappa,Jérôme Paillassa et al.
Urbain Tauveron-Jalenques et al.
Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion-dependent β-thalassaemia [0.03%]
输血依赖性β-地中海贫血疾病严重程度、输血影响和遗传背景的红细胞膜蛋白质组报告指标
Konstantina Theocharaki,Sophia Delicou,Aikaterini Ntzoura-Kani et al.
Konstantina Theocharaki et al.
Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion-dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults ...
Lamya Garabet,Waleed Ghanima
Lamya Garabet
Patients with immune thrombocytopenia (ITP) have a higher thrombotic rate than the general population, and certain ITP treatments may further increase this risk. This narrative 'In a Nutshell' review provides an overview on thrombosis in ad...
Checkpoint inhibitors, obinutuzumab plus PET-adapted ultra-low dose nodal radiotherapy yield high efficacy in treatment-naïve follicular lymphoma: Results from the phase II 'FLUORO' study [0.03%]
检查点抑制剂联合奥英妥珠单抗及正电子发射断层扫描(PET)导向超低剂量瘤区放疗治疗初治滤泡性淋巴瘤的Ⅱ期“FLUORO”研究结果
Arina Martynchyk,Geoffrey Chong,Richard Khor et al.
Arina Martynchyk et al.
Follicular lymphoma (FL) first-line chemoimmunotherapy yields high efficacy but serious toxicity in 65% of patients. In high tumour burden treatment-naïve FL, we aimed to exploit known immunostimulatory and cytotoxic properties of combinat...