Contemporary global burden of sickle cell anaemia under-5 and under-20: A systematic review and meta-analysis [0.03%]
镰状细胞贫血的全球负担系统评价和荟萃分析
Kelly Pimenta,Jeffrey Edwards,Meredith Ray et al.
Kelly Pimenta et al.
Sickle cell disease (SCD), a prevalent inherited non-communicable disease, remains a neglected public health priority, especially children and adolescents in many low- and middle-income countries. The global burden of SCD in youth remains u...
Real-world treatment patterns and outcomes in accelerated and blast-phase myeloproliferative neoplasms: Insights from a large multi-centre cohort analysis in the United Kingdom [0.03%]
英国大规模多中心队列分析加速期和急变期骨髓增殖性肿瘤的治疗模式及结局
Alexandros Rampotas,Gabriel Naylor-Layland,Clare Brown et al.
Alexandros Rampotas et al.
This UK-based retrospective analysis describes real-world treatment patterns and outcomes in 175 patients with accelerated (AP, n = 69) or blast-phase (BP, n = 106) 'Philadelphia-negative' myeloproliferative neoplasms (MPN-AP/BP) diagnosed ...
Integrated proteomic and metabolomic profiling reveals sex-stratified biomarkers predicting chronicity in paediatric primary immune thrombocytopenia [0.03%]
整合蛋白质组和代谢组谱型可揭示儿科原发性免疫性血小板减少症慢性化的性别分层生物标志物
Yuanyuan Xue,Rongrong Zhang,Dongmei Liang et al.
Yuanyuan Xue et al.
This study aimed to develop prediction models for chronic immune thrombocytopenia (ITP) using a sex-stratified proteomic and metabolomic approach, providing a framework for individualized prognosis evaluation and timely clinical management....
Blastic plasmacytoid dendritic cell neoplasm (BPDCN): Morphological mimicry of lymphoid neoplasms [0.03%]
原始浆细胞样树突状细胞肿瘤(BPDCN)的形态学模仿淋巴瘤
Hong Guo,Yan Wei,Chenglei Wang et al.
Hong Guo et al.
Prospective implementation of the HCT frailty scale in adults with lymphoproliferative syndromes candidates for autologous haematopoietic stem cell transplantation: Results from a multicentre GETH-TC study [0.03%]
HCT衰弱量表在自体造血干细胞移植前淋巴增生性综合征成人患者中的前瞻性实施:GETH-TC多中心研究结果
Javier Cornago,Mónica Baile,Marina Acera et al.
Javier Cornago et al.
This prospective study evaluated the incidence and dynamics of frailty in 156 adults with lymphoproliferative syndromes undergoing autologous haematopoietic stem cell transplantation (HSCT). Frailty was assessed using the haematopoietic cel...
Real-world comparison of peripheral neuropathy and treatment delivery between Pola-R-CHP and R-CHOP in DLBCL [0.03%]
DLBCL中Pola-R-CHP与R-CHOP外周神经毒性及治疗实施的现实世界比较分析
Nobuhiko Nakamura,Koichi Ohata,Tomohiro Aizaki et al.
Nobuhiko Nakamura et al.
Circulating erythropoietin concentration associates with thromboembolism in sickle cell disease [0.03%]
促红细胞生成素浓度与镰状细胞病患者的血栓事件有关
Xu Zhang,Binal N Shah,Jin Han et al.
Xu Zhang et al.
Elevated erythropoietin (EPO) concentration associates with thrombotic risk in hypoxic conditions, hereditary erythrocytosis and treatment of anaemia with recombinant EPO. We evaluated sickle cell disease (SCD) patients from the University ...
Deacetylase inhibitors CM-444 and CM-1758 enhance chemotherapy response in AML via ALOX5 [0.03%]
脱乙酰酶抑制剂CM-444和CM-1758通过ALOX5增强AML的化学治疗反应
Naroa Gimenez-Camino,Edurne San José-Enériz,Leire Garate et al.
Naroa Gimenez-Camino et al.
HLA profile in paediatric ITP: Comparison with healthy controls and prognostic implications [0.03%]
儿童ITP的HLA表型与健康对照的比较及其预后意义
Jesús González de Pablo,Yessenia L Molina,José Luis Vicario et al.
Jesús González de Pablo et al.
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated low platelet counts. Although several studies have explored the relationship between the human leucocyte antigen (HLA) system and ITP, findings have been inco...