Genomic Insights Into Genetic Diversity and Population Structure of Pastoral 'Belahi' Cattle of North Himalayan (Shivalik) Foothills [0.03%]
基因组学视角下的北喜马拉雅山脚牧养“贝尔哈伊”牛的遗传多样性和种群结构研究
Ashish Yadav,Kashif Dawood Khan,Shambhuraditya Chavan et al.
Ashish Yadav et al.
Pastoral cattle breeding sustains nomadic communities by conserving local and non-commercial but valuable genetic resources. The aim of this study was to understand the genetic structure and diversity of newly registered pastoral Belahi cat...
A Cross-Species Single-Cell Transcriptomic Atlas of Subcutaneous Adipose Tissue Reveals Conserved and Divergent Cellular Programs [0.03%]
跨物种皮下脂肪组织单细胞转录组图谱揭示了保守和分歧的细胞程序
Xinran Niu,Liwei Zhai,Lulu Wang et al.
Xinran Niu et al.
Adipose tissue is not only the primary site of energy storage but also an essential metabolic organ for maintaining energy homeostasis to regulate adipogenesis, metabolism, and chronic inflammation in mammals. However, the cross-species con...
Impact of Varying Soybean Oil Concentrations on the Cytokine Profile of Skeletal Muscle and Liver of Pigs: A Systems Biology Approach [0.03%]
不同浓度的大豆油对猪骨骼肌和肝脏细胞因子的影响：系统生物学方法研究
Fernanda Nery Ciconello,Julia Dezen Gomes,Simara Larissa Fanalli et al.
Fernanda Nery Ciconello et al.
Lipids are important for metabolic processes, mainly cytokine regulation in the skeletal muscle and liver. Considering the soybean oil concentration, a weighted gene co-expression network analysis (WGCNA) was used to perform an integrative ...
Genetic Basis of Growth and Carcass Traits in Sansui Duck Identified Through Genome-Wide Association Analysis [0.03%]
利用全基因组关联分析鉴定三穗鸭生长及胴体性状的遗传基础
Yulong Feng,Mengru Xu,Ziheng Cai et al.
Yulong Feng et al.
The Sansui duck is a valuable Chinese genetic resource. However, incomplete exploration of its genetic resources has limited the full utilization of its genetic potential. This study systematically evaluated the growth and carcass performan...
Genomic Variation and Population Structure of Portuguese Native Dog Breeds [0.03%]
葡萄牙土狗品种的基因组变异和种群结构
Ludmilla Blaschikoff,Octávio Serra,Fernanda Simões et al.
Ludmilla Blaschikoff et al.
The presence of dogs in Portugal is confirmed by zooarchaeological evidence dating to at least 7600 years ago. The 11 native dog breeds that exist in this territory are therefore the end-product of a complex evolutionary process. This study...
Reproducibility of the Evaluation of Genetic Variant Pathogenicity Based on the Animal Variant Classification Guidelines [0.03%]
基于动物变异分类指南的基因变异致病性评估的可重复性
Iris Casselman,Carlotta Ferrari,Marie Abitbol et al.
Iris Casselman et al.
Until recently, due to the absence of standardized guidelines tailored for veterinary use, the evaluation of genetic variant pathogenicity for single-gene diseases was based on a personal interpretation of the presented evidence, which has ...
Polygenic Prediction of Equestrian Sport Discipline Among Horses Bred for Jumping and Dressage [0.03%]
多基因预测马匹跳跃和盛装舞步项目的优劣性状遗传力及育种值估算
Emmeline W Hill,Haige Han,Amy R Holtby et al.
Emmeline W Hill et al.
Horses bred for different equestrian sports vary in physical, physiological and behavioural requirements. Characterising genetic markers associated with discipline provides an opportunity to improve identification of horses best suited to e...
Integrated Circular RNAs Analysis Across the Hypothalamic-Pituitary-Ovarian Axis Identifies Regulatory Modules Shaping Reproductive Traits in Geese [0.03%]
整合分析鹅下丘脑-垂体-卵巢轴的环形RNA，鉴定出成形生殖性状的调控模块
Linhong Xie,Zhonglong Zhao,Yonghong Zhang et al.
Linhong Xie et al.
Circular RNAs (circRNAs) are increasingly recognized as key post-transcriptional regulators. However, their functions within the avian hypothalamic-pituitary-ovarian (HPO) axis remain poorly understood. To investigate potential associations...
SOCS2 Negatively Regulates Proliferation and Adipogenic Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells [0.03%]
SOCS2通过抑制猪脂肪来源的间充质干细胞增殖和促进其成脂分化负调控其成骨分化
Haoran Shi,Lin Chen,Jing Gao et al.
Haoran Shi et al.
Suppressor of cytokine signaling 2 (SOCS2) is a classical feedback inhibitor of JAK-STAT signaling, but its role in porcine adipose-derived mesenchymal stem cells (PADSCs) and fat deposition remains unclear. Here, we investigated the functi...
Heritability Patterns of Protein-Coding Genes Expression: Insights From the Pig Genotype-Tissue Expression Project [0.03%]
猪基因型-组织表达项目的蛋白质编码基因的遗传力模式及其启示
Chao Su,Wenjing Zhang,Wenzhe Ning et al.
Chao Su et al.
Understanding the genetic basis of gene expression is crucial for elucidating the mechanisms underlying complex traits, especially for protein-coding genes (PCGs) whose expression levels directly affect protein abundance and functionality. ...