Neuronal ceroid lipofuscinosis in Salukis is caused by a single base pair insertion in CLN8 [0.03%]
一个碱基对的插入导致了滑鹿犬中的神经元脑苷脂贮积病CLN8型
F Lingaas,O-A Guttersrud,E Arnet et al.
F Lingaas et al.
Neuronal ceroid lipofuscinoses (NCLs) are heterogenic inherited lysosomal storage diseases that have been described in a number of species including humans, sheep, cattle, cats and a number of different dog breeds, including Salukis. Here w...
Case Reports
Animal genetics. 2018 Feb;49(1):52-58. DOI:10.1111/age.12629 2018
A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits [0.03%]
猪肥胖相关性状功能基因鉴定的靶向分型方法及味觉受体和食欲/奖赏类基因变异特征研究
S Cirera,A Clop,M J Jacobsen et al.
S Cirera et al.
Taste receptors (TASRs) and appetite and reward (AR) mechanisms influence eating behaviour, which in turn affects food intake and risk of obesity. In a previous study, we used next generation sequencing to identify potentially functional mu...
Genome-wide association analysis reveals the common genetic locus for both the typical and atypical polycerate phenotype in Tibetan sheep [0.03%]
全基因组关联分析发现西藏羊多胚类型共有遗传位点
Xiaohong He,Shen Song,Xiaofei Chen et al.
Xiaohong He et al.
A splice site variant in the SUV39H2 gene in Greyhounds with nasal parakeratosis [0.03%]
SUV39H2基因剪接位点突变导致的灵缇鼻部鳞状上皮化生综合征
A Bauer,J Nimmo,R Newman et al.
A Bauer et al.
Hereditary nasal parakeratosis (HNPK), described in the Labrador Retriever breed, is a monogenic autosomal recessive disorder that causes crusts and fissures on the nasal planum of otherwise healthy dogs. Our group previously showed that th...
Genome-wide association study for reproductive traits in a Large White pig population [0.03%]
用于大白猪群体繁殖性状的全基因组关联分析
Y Wang,X Ding,Z Tan et al.
Y Wang et al.
Using the PorcineSNP80 BeadChip, we performed a genome-wide association study for seven reproductive traits, including total number born, number born alive, litter birth weight, average birth weight, gestation length, age at first service a...
Genomic variation in Pekin duck populations developed in three different countries as revealed by whole-genome data [0.03%]
来自全世界的北京鸭基因组变异全解析
Z Zhang,Y Jia,Y Chen et al.
Z Zhang et al.
It is well known that both British and American Pekin ducks originated from China. However, the populations differ substantially in production performance, but the genetic changes involved are still poorly understood. Herein, we sequenced 2...
An analysis of effects of heterozygosity in dairy cattle for bovine tuberculosis resistance [0.03%]
奶牛杂合子对抵抗牛型结核病的影响分析
S Tsairidou,A R Allen,R Pong-Wong et al.
S Tsairidou et al.
Genetic selection of cattle more resistant to bovine tuberculosis (bTB) may offer a complementary control strategy. Hypothesising underlying non-additive genetic variation, we present an approach using genome-wide high density markers to id...
Exclusion of adrenoceptor alpha 2 variants in a horse insensitive to medetomidine [0.03%]
排除一类肾上腺素能受体变异型与对美托咪啶不敏感的马的关系
Isabelle Schmutz,Vidhya Jagannathan,Sabina Diez Bernal et al.
Isabelle Schmutz et al.
Case Reports
Animal genetics. 2018 Apr;49(2):141. DOI:10.1111/age.12636 2018
A Bauer,A Kehl,V Jagannathan et al.
A Bauer et al.
Coat colour dilution may be the result of altered melanosome transport in melanocytes. Loss-of-function variants in the melanophilin gene (MLPH) cause a recessively inherited form of coat colour dilution in many mammalian and avian species ...
Genome-wide population structure and admixture analysis reveals weak differentiation among Ugandan goat breeds [0.03%]
全基因组范围的群体结构和杂交分析揭示了乌干达山羊品种间的微弱分化
R B Onzima,M R Upadhyay,R Mukiibi et al.
R B Onzima et al.
Uganda has a large population of goats, predominantly from indigenous breeds reared in diverse production systems, whose existence is threatened by crossbreeding with exotic Boer goats. Knowledge about the genetic characteristics and relati...