Structure-based design and evaluation of synthetic porphyrin derivatives as G-quadruplex stabilizing anticancer agents [0.03%]
基于结构的设计和评估合成的卟啉衍生物作为稳定G-四链体的抗肿瘤剂
R N Bhadane,D B Meshram,R M Gilhotra
R N Bhadane
G-quadruplex structures formed in telomeres and proto-oncogene represent a potentially useful target for anticancer drugs. Stabilization of this arrangement may inhibit the further action of different enzymes involved in cancer cell immorta...
Awareness on cytology procedure in oral cancer detection among undergraduates: An institutional study [0.03%]
口腔癌检测细胞学检查在校大学生中的认知度调查——一项机构研究
Gayathri Ramesh,Rajeev Pathak,Sunita Pathak et al.
Gayathri Ramesh et al.
Background: The screening and the early detection of the premalignant and malignant lesions are the only means for controlling the oral cancer which is known to be one of the leading causes for mortality worldwide. Oral e...
The influence of different peptide combinations to increase the immunogenicity of the Gonadotrophin Releasing Hormone Vaccine for prostate cancer treatment [0.03%]
不同肽组合对提高促性腺激素释放素疫苗抗前列腺癌免疫原性的影响
Franklin Fuentes Aguilar,Jesús Junco Barranco,Lesvia Calzada Aguilera et al.
Franklin Fuentes Aguilar et al.
Purpose: Therapeutic vaccines, specifically the Gonadotrophin Releasing Hormone (GnRH) vaccine, are considered an additional therapeutic option for advanced stage prostate cancer. Our work showed amplification of the immu...
Population-specific genetic variation at microRNA-629-binding site in the 3'-UTR of NBS1 gene in prostate cancer patients [0.03%]
前列腺癌患者中NBS1基因的3'UTR区域microRNA-629结合位点上的群体特异性遗传多态性研究
Ammad Ahmad Farooqi,Syed M Kamran Majeed,Qaisar Mansoor et al.
Ammad Ahmad Farooqi et al.
Objective: Prostate cancer is a genomically complex disease and recently emerging scientific evidence is adding new pieces of information into existing pool of knowledge of oncology. Prostate cancer cells tactfully rewire...
Lipoma of round ligament on the intraperitoneal portion (abdominal site): a case report [0.03%]
腹腔内圆韧带脂肪瘤一例报告
Ozhan Ozdemır,Mustafa Erkan Sarı,Vefa Selimova Sakar et al.
Ozhan Ozdemır et al.
Primary tumors of round ligament are rare, and when found are typically leiomyomas. Endometrioma, and mesothelial cysts are the benign lesions recognized as involving the round ligament. We report a case of lipoma of the round ligament in a...
Cystic lymphangioma of the lesser omentum in a pregnant woman: a case report and review of the literature [0.03%]
肝小网囊状淋巴管瘤一例并文献复习
Ozhan Ozdemir,Mustafa Erkan Sarı,Cemal Resat Atalay et al.
Ozhan Ozdemir et al.
Lymphangiomas are rare benign tumors which are generally seen in pediatric population and the etiopathogenesis has not yet been understood. They occasionally occur in the head and neck or axillary region with only 5% of them being located i...
Renuka Gupta,Madhusudan Astekar,Ramakant Dandriyal et al.
Renuka Gupta et al.
One challenging feature of head and neck pathology is that a dizzying array of spindle cell lesions occurs here which ranges all the way from reactive, very aggressive forms to malignant lesions. Leiomyosarcoma is one such malignant tumour ...
Effect of lupeol on antioxidants and xenobiotic enzymes in N-Butyl-N-(4-hydroxybutyl) nitrosamine induced bladder carcinogenesis in experimental rats [0.03%]
Lupeol对N-丁基-N-(4-羟基丁基)亚硝胺致实验大鼠膀胱癌变抗氧化剂和外源性酶的影响
Bhoopathy Prabhu,Annamalai Sivakumar,Doraisami Balakrishnan et al.
Bhoopathy Prabhu et al.
Urothelial carcinoma of the bladder is a common malignancy ranked 9th with an estimated 356,600 new cases diagnosed annually worldwide. The study showed the protective effects of Lupeol in N-Butyl-N-(4-hydroxybutyl) nitrosamine induced blad...
Salivary lactate dehydrogenase as a prognostic marker in oral squamous cell carcinoma patients following surgical therapy [0.03%]
术后唾液乳酸脱氢酶作为口腔鳞状细胞癌患者预后标志物的研究
Varsha Pathiyil,Audrey Madonna DCruz
Varsha Pathiyil
The objective of the present study was to assay the salivary levels of lactate dehydrogenase in patients with OSCC in comparison to healthy controls and to assess the changes in salivary levels of lactate dehydrogenase as prognostic markers...
Poly-MVA attenuates 7,12- dimethylbenz[a]anthracene initiated and croton oil promoted skin papilloma formation on mice skin [0.03%]
聚棓鉻鞣酸酯可抑制苯并蒽诱发的小鼠皮肤乳头状瘤形成
Ravindran K Veena,Thekkuttuparambil A Ajith,Kainoor K Janardhanan et al.
Ravindran K Veena et al.
Chemopreventive agents which exhibit activities such as anti-inflammation, inhibition of carcinogen induced mutagenesis and scavenging of free radical might play a decisive role in the inhibition of chemical carcinogenesis either at the ini...