Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA [0.03%]
表达胰岛素样生长因子I受体反义RNA的细胞可使大鼠脑C6肿瘤退化
M Resnicoff,J Tjuvajev,H L Rotman et al.
M Resnicoff et al.
We have previously shown that C6 cells expressing an antisense insulin-like growth factor I receptor (IGF-IR) RNA are no longer tumorigenic in syngeneic rats, protecting them from subsequent subcutaneous tumor challenge and causing regressi...
Induction of apoptosis in an androgen-independent mouse cell line by transforming growth factor-beta 1 [0.03%]
转化生长因子-β1诱导雄激素非依赖性小鼠细胞系发生凋亡
Y Furuya,S Ohta,J Shimazaki
Y Furuya
Androgen-dependent tumors eventually progress to androgen-independent tumors after androgen withdrawal. Androgen-independent CS2 cells could grow in serum-free culture whether androgen is present in the medium or not. In the present study, ...
Induction of resistance in the human leukemia cell line HL60 towards hexadecylphosphocholine and other ether phospholipid analogues [0.03%]
十六烷基磷胆碱和其他醚型类似物类对人白血病细胞系HL60耐药性的诱导作用
D Berkovic,D Haase,W Hiddemann et al.
D Berkovic et al.
Hexadecylphosphocholine (HePC) is a new ether lipid analogue with remarkable antineoplastic activity in vitro and in vivo. As the precise molecular mechanism by which this substance and probably other ether lipids exert their biological eff...
Quantitative measurements of the efficacy of new anti-cancer agents on fresh human AML cells by using multivariate flow analysis [0.03%]
采用多变量流式分析法对新鲜的人类急性髓性白血病细胞进行新型抗肿瘤药物疗效的定量检测
A Nakeff,M A KuKuruga,J E Media et al.
A Nakeff et al.
The testing of new human leukemia-specific drugs for activity against primary acute myeloid leukemia (AML) blasts is severely limited by the low and variable clonogenic potential of primary human leukemias in culture. To circumvent this pro...
Lymphocyte number and stress parameter modifications in untreated breast cancer patients with depressive mood and previous life stress [0.03%]
未经治疗的乳腺癌患者抑郁和既往生活压力对淋巴细胞数量和应激参数的影响
M Aragona,M R Muscatello,E Losi et al.
M Aragona et al.
Depressive mood disorders and severe, chronic stressful life events (DSM-III-R criteria) were more frequently diagnosed in 106 breast cancer patients with respect to 37 patients with benign breast diseases (control group) (p < 0.001), durin...
Clinical Trial
Journal of experimental therapeutics & oncology. 1996 Nov;1(6):354-60. DOI: 1996
M Aragona,F Aragona
M Aragona
Estrogens are known to have mitogenic activities and to influence hematic crasis. A wide literature on this subject allows us to re-evaluate the results of research performed in 1950. Estrogens injected into the peritoneum (estradiol propio...
Stimulation of GALT and activation of mesenteric lymph node lymphocytes by a modified lysozyme in CBA mice with MCa mammary carcinoma [0.03%]
修饰的溶菌酶对CBA携带MCa乳腺癌小鼠GALT和肠系膜淋巴结淋巴细胞的激发作用
G Sava,A Bergamo,I Capozzi et al.
G Sava et al.
Lysozyme (hen egg-white lysozyme) and its derivative mPEG-lyso (lysozyme coupled with polyoxyethyleneglycol) were tested in CBA mice bearing MCa mammary carcinoma for their effects on intestinal mucosal immunity (GALT) and mesenteric lymph ...
The association of the H-ras oncogene and steroid hormone receptors in gynecological cancer [0.03%]
H-ras癌基因与妇科肿瘤激素受体的关系研究
G Zachos,M Varras,M Koffa et al.
G Zachos et al.
Expression of the ras family of cellular oncogenes is associated with tumorigenicity, invasiveness and metastatic potential in a variety of human carcinomas. Additionally, H-ras cooperates with glucocorticoids and with ovarian hormones in c...
Establishment of human prostate tumor xenografts in nude mice and response to 9-nitrocamptothecin in vivo and in vitro does not correlate with the expression of various apoptosis-regulating proteins [0.03%]
人前列腺肿瘤异种移植裸鼠模型的建立及其体内、外对鬼臼毒素衍生物NK的效果与其凋亡调控蛋白表达之间的关系研究
P Pantazis,D Chatterjee,J Wyche et al.
P Pantazis et al.
Flow cytometry and microscopy analyses have demonstrated that 9-nitrocamptothecin (9NC) induces apoptosis in prostate carcinoma LNCaP, DU-145 and PC-3 cells grown in culture or as xenografts. 9NC induces apoptosis regardless of the ability ...
Ki-67 and p53 immunoreactive stain and early colorectal neoplasms [0.03%]
Ki-67和p53免疫反应染色与早期结肠直肠肿瘤的关系
S Hirota,S Hosobe,M Ikeda et al.
S Hirota et al.
The aim of this work was to conduct a histopathological study of the different pathways of colorectal tumorigenesis by using Ki-67 and p53 immunoreactive stains. Between 1987 and 1993, 14,023 patients were investigated by colonoscopy at Aki...