Differential expression of retinoic acid receptors in normal and malignant esophageal tissues [0.03%]
正常和恶性食管组织中视黄酸受体的差异表达
Anupam Kumar,Jatinder Kaur,Tushar Kant Chattopadhyay et al.
Anupam Kumar et al.
The chemopreventive and chemotherapeutic activities of retinoids may be attributed to their ability to modulate growth, differentiation and apoptosis of epithelial cells, suppress or reverse epithelial carcinogenesis. Many of these effects ...
Comparative Study
Journal of experimental therapeutics & oncology. 2004 Apr;4(1):1-8. DOI: 2004
Antitumor effect of stilbenoids from Vateria indica against allografted sarcoma S-180 in animal model [0.03%]
文藤胶脂没药树茋类化合物的抗肿瘤作用研究
Satoshi Mishima,Kenji Matsumoto,Yoshihiro Futamura et al.
Satoshi Mishima et al.
Dipterocarpaceous plants contain various resveratrol oligomers that exhibit a variety of biological activities, such as antibacterial and antitumor effects. Previously, we found that vaticanol C, a resveratrol tetramer, exhibits strong cyto...
Combining doxorubicin and liposomal anti-HER-2/NEU antisense oligodeoxynucleotides to treat HER-2/NEU-expressing MDA-MB-435 breast tumor model [0.03%]
多柔比星和脂质体抗HER-2/neu反义寡核苷酸联合治疗HER-2/neu表达的乳腺癌MDA-MB-435肿瘤模型的研究
Dawn N Waterhouse,Karen A Gelmon,Dana Masin et al.
Dawn N Waterhouse et al.
This study assessed the in vivo therapeutic activity of an antisense molecule targeted against HER-2/neu expressing mRNA. Antisense activity was evaluated in female SCID/Rag2m mice bearing subcutaneous tumors derived from HER-2/neu-transfec...
Vanadium suppresses sister-chromatid exchange and DNA-protein crosslink formation and restores antioxidant status and hepatocellular architecture during 2-acetylaminofluorene-induced experimental rat hepatocarcinogenesis [0.03%]
钒抑制联体染色体交换和DNA-蛋白质交联的形成，并在2-乙酰氨基芴诱导的大鼠实验性肝癌发生过程中恢复抗氧化状态和肝细胞结构
Tridib Chakraborty,Shilpi Ghosh,Subroto Datta et al.
Tridib Chakraborty et al.
Vanadium is an important regulator of cellular growth, differentiation, and cell death, and thus has received increasing attention to be an effective cancer chemopreventive agent. In the present study, attempts have been made to investigate...
Inhibition of indoleamine 2,3-dioxygenase suppresses NK cell activity and accelerates tumor growth [0.03%]
色氨酸酶2,3-双氧化酶的抑制能够抑制自然杀伤细胞活性并促进肿瘤生长
Seiichiro Kai,Shigeru Goto,Kouichirou Tahara et al.
Seiichiro Kai et al.
Indoleamine 2,3-dioxygenase (IDO), a tryptophan catabolizing enzyme, is induced under various pathological conditions, including viral and bacterial infection, allograft rejection, cerebral ischemia, and tumor growth. We have previously rep...
Laser-assisted microdissection applied to frozen surgical pathologic specimens - methodological aspects on RT-PCR [0.03%]
激光辅助微解剖在冷冻手术病理标本中的应用及其对RT-PCR的方法学影响
Isabelle Saal,Anne Gustin,Katia Rombaut et al.
Isabelle Saal et al.
Laser-assisted microdissection has become a unique technique for an accurate gene-expression profiling analysis in human tissues. The introduction of this approach requires the development of a reliable, efficient, and reproducible procedur...
Regulation of cathepsin B and L expression in vitro in gastric cancer tissues by egg cystatin [0.03%]
鸡蛋囊抑素对体外培养胃癌组织中猫HEPSIN-B和L表达的调节作用
Yousif Saleh,Maciej Siewiński,Wojciech Kielan et al.
Yousif Saleh et al.
Background: Degradation of the basement membrane and surrounding extracellular matrix is likely to represent a key step in cancer invasion and metastasis. The purpose of this study was to determine whether gastric cancer ...
Evan Pisick,Simha Jagadeesh,Ravi Salgia
Evan Pisick
Small cell lung cancer (SCLC) is an aggressive tumor which metastasizes early. Patients with this disease have a poor prognosis even with immediate treatment. Because of the aggressive nature of this disease, all aspects of this tumor are s...
Raghunandan Dudda-Subramanya,Guglielmo Lucchese,Darja Kanduc et al.
Raghunandan Dudda-Subramanya et al.
Microarray technology provides a revolutionary macro-genetic and bioinformatic-rich platform for understanding human diseases. DNA microarrays facilitate the study of complex diseases, enabling several observations simultaneously that can b...
Alteration of the fragile histidine triad gene early in carcinogenesis: an update [0.03%]
脆性组氨酸三联密码基因在肿瘤发生早期的改变：最新研究进展
Hideshi Ishii,Keiya Ozawa,Yusuke Furukawa
Hideshi Ishii
An association between common chromosome fragile sites and frequent chromosomal deletions in cancer has been observed and led to the hypothesis that genes at fragile sites may play a role in tumor development. In 1996, the human fragile his...