Radioimmunotherapy in non-Hodgkin's lymphoma: focus on 90Y-ibritumomab tiuxetan (Zevalin) [0.03%]
非霍奇金淋巴瘤的放射免疫治疗：以90Y-ibritumomab tiuxetan(Zevalin)为重点
Christine A White
Christine A White
Radioimmunotherapy (RIT), in which a radionuclide conjugated to an antibody directed towards a tumor associated antigen (the radioimmunoconjugate) is administered in a therapeutic regimen, represents a significant addition to the treatment ...
The importance of the CXCL12-CXCR4 chemokine ligand-receptor interaction in prostate cancer metastasis [0.03%]
趋化因子配体-受体相互作用CXCL12-CXCR4在前列腺癌转移中的重要作用
Manit Arya,Hitendra R H Patel,Claire McGurk et al.
Manit Arya et al.
Aim: Chemokines or chemotactic cytokines are known to be important in the directional migration or chemotaxis of leucocytes in conditions of homeostasis and in inflammatory or immunological responses. However, the role of...
Inhibition of TF gene expression by antisense oligonucleotides in different cancer cell lines [0.03%]
反义寡核苷酸在不同癌细胞系中抑制TF基因表达
Yvonne Förster,Bernd Schwenzer
Yvonne Förster
Human tissue factor (TF) is the initiator of blood coagulation. Beside this function it is involved in tumor angiogenesis and metastasis. In the study we have evaluated the efficiency of antisense oligonucleotides (AS-ODNs) against TF selec...
Kunwar Shailubhai,Surendra Dheer,Donald Picker et al.
Kunwar Shailubhai et al.
Atiprimod, a novel compound belonging to the azaspirane class of cationic amphiphilic drugs, exhibits both anti-proliferative and anti-angiogenic activities. Atiprimod inhibited proliferation of all human cancer cell lines included in the N...
The 24th International Symposium of Sapporo Cancer Seminar "Pharmacogenomics in Cancer Chemotherapy: Recent Advances in ABC Transporters and Genome Analyses". Hokkaido University Conference Hall, Sapporo, Japan, June 20-22, 2004 [0.03%]
第24届札幌癌症研讨会国际会议：“肿瘤化疗中的药物基因组学：最近有关ABC转运蛋白和基因组分析的研究进展”。日本札幌，北海道大学会议厅，2004年6月20至22日
Toshihisa Ishikawa
Toshihisa Ishikawa
The monitoring of the accumulation of protoporphyrin IX in Walker tumours by subcutaneous administration of delta-aminolevulinic acid [0.03%]
通过皮下注射氨基乙酰丙酸监测Walker肿瘤中原卟啉Ⅸ的蓄积
Mihaela Antonina Calin,Maria luliana Gruia,Nicoleta Herascu et al.
Mihaela Antonina Calin et al.
Photodynamic therapy with protoporphyrin IX induced by delta-aminolevulinic acid (ALA) is mainly applied for the treatment of human superficial skin cancer. In this paper we present our study on photodynamic therapy (PDT) of the implanted W...
Human ATP-binding cassette transporter ABCC10: expression profile and p53-dependent upregulation [0.03%]
人ATP结合盒转运蛋白ABCC10：表达谱及p53依赖性上调作用
Shin-Ichiro Takayanagi,Takao Kataoka,Osamu Ohara et al.
Shin-Ichiro Takayanagi et al.
Human ATP-binding cassette (ABC) transporter genes are classified into seven sub-families, where "C" subfamily comprises a total of 13 gene members. The ABCC10 cDNA was cloned in the human full-length cDNA project at the Kazusa DNA Research...
Comparative Study
Journal of experimental therapeutics & oncology. 2004 Oct;4(3):239-46. DOI: 2004
3-amino thioacridone inhibits DNA synthesis and induce DNA damage in T-cell acute lymphoblastic leukemia (T-ALL) in a p16-dependent manner [0.03%]
3-氨基硫杂阿司匹林通过依赖p16的方式抑制DNA合成及T细胞急性淋巴细胞白血病(T-ALL)诱导DNA损伤
Mitchell B Diccianni,John Yu,Gerda Meppelink et al.
Mitchell B Diccianni et al.
In T-cell Acute Lymphocytic Leukemia (T-ALL), the inhibitors of cyclin-dependent kinases (CDK) 4 and 6, p16 and p15, are inactivated almost universally at the DNA, RNA and protein levels. This suggests that CDK-targeting may be an effective...
Implications of p53 in growth arrest and apoptosis on combined treatment of human Mammary epithelial cells with topotecan and UCN-01 [0.03%]
拓扑替康与UCN-01联合处理的人乳腺上皮细胞中p53在增殖抑制和凋亡中的意义
Alka Redkar,Phillip Mixter,Sayed S Daoud
Alka Redkar
We previously reported (Cancer Chemother Pharmacol 45: 252-258, 2000) that UCN-01 (7-hydroxystaurosporine), a protein kinase inhibitor, which is under clinical trials as an anti-cancer agent in the USA and Japan, enhanced camptothecin-induc...
Protective effect of a polyherbal preparation, Brahma rasayana against tumor growth and lung metastasis in rat prostate model system [0.03%]
婆罗摩滋阴汤(Brahma Rasayana)对前列腺癌移植瘤生长及肺转移的抑制作用研究
Jaya P Gaddipati,N V Rajeshkumar,Rajesh L Thangapazham et al.
Jaya P Gaddipati et al.
Rasayanas are a group of herbal formulations and are used to improve health of the body. Recent studies have demonstrated the immunostimulatory and antioxidant activities of some of these rasayanas and their usefulness in tumor regression. ...