American ginseng (Panax quinquefolius L.) extract alters mitogen-activated protein kinase cell signaling and inhibits proliferation of MCF-7 cells [0.03%]
美国人参（Panax quinquefolius L.）提取物可改变有丝分裂原活化蛋白激酶细胞信号传导并抑制MCF-7细胞增殖
Mandy L King,Laura L Murphy
Mandy L King
Ginseng has been shown to inhibit cancer cell proliferation and tumor growth, however the mechanisms underlying this inhibition have yet to be elucidated. An inhibitory effect of hot water-extracted American ginseng (Panax quinquefolius L.)...
Differential protein expression patterns obtained by mass spectrometry can aid in the diagnosis of Hodgkin's disease [0.03%]
基于质谱技术的差异蛋白质表达模式有助于霍奇金病的诊断
Paulo Costa Carvalho,Maria da Gloria Costa Carvalho,Wim Degrave et al.
Paulo Costa Carvalho et al.
More than 90% of patients with cancer, if diagnosed early, can be promptly treated; however diagnosis usually occurs after cancer cells have metastasized. Recent technological advances in mass spectrometry challenges the field of machine le...
A nanoemulsion of an anti-oxidant synergy formulation reduces tumor growth rate in neuroblastoma-bearing nude mice [0.03%]
一种抗氧化协同作用纳米乳剂可降低裸鼠神经母细胞瘤生长速率
Fonghsu Kuo,Timothy Kotyla,Thomas Wilson et al.
Fonghsu Kuo et al.
Neuroblastoma, the most common form of childhood cancer, may arise from a biochemical block of cellular differentiation and a resultant continuation of a proliferative state. Neuroblastoma often spontaneously reverts by undergoing partial d...
Dip1 inhibits growth and gene transcription in MCF-7 breast cancer cells [0.03%]
Dip1通过抑制基因转录抑制MCF-7乳腺癌细胞生长
Tao Su,Atsuko Deguchi,Yao Yao et al.
Tao Su et al.
In previous studies we identified a novel gene Dipl, also designated CCNDBP1, which encodes a 42kDa helix-loop-helix (HLH) nuclear protein. Although this protein was originally identified by its ability to bind to cyclin D1 its precise bioc...
Antitumor and immunomodulatory effect of coumarin and 7-hydroxycoumarin against Sarcoma 180 in mice [0.03%]
香豆素和7-羟基香豆素的抗肿瘤及免疫调节作用研究
Tsvetanka H Stefanova,Nadya J Nikolova,Reneta A Toshkova et al.
Tsvetanka H Stefanova et al.
The antitumor effect of peroral treatment with coumarin and its main metabolite in humans 7-hydroxycoumarin (7-OHC) against Sarcoma 180 in mice was studied. Both agents inhibited tumor growth and increased survival time of tumor-bearing ani...
Milk-derived proteins and peptides of potential therapeutic and nutritive value [0.03%]
具有潜在治疗和营养价值的乳源蛋白和肽
Michal Zimecki,Marian L Kruzel
Michal Zimecki
Milk and colostrum are rich in proteins and peptides which play a crucial role in development of the immune system in mammalian offspring. Immunotropic properties of these compounds prompted investigators to search for their utility in prev...
Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers [0.03%]
肿瘤时间生物学III. 肿瘤、衰老、褪黑素和实验治疗研究的时间生物学
Franz Halberg,Germaine Cornélissen,Waldemar Ulmer et al.
Franz Halberg et al.
This position paper documents the merit of including for basic and clinical investigations the mapping of circadian and other rhythms and yet broader chronomes, time structures in and around us. Chronobiometry used herein relies on inferent...
Germaine Cornélissen,Mikhail Victorovich Berezkin,Elena V Syutkina et al.
Germaine Cornélissen et al.
This paper is a memorial to Mikhail Victorovich Berezkin (MVB) (10 April 1940 - 16 January 2005), an enthusiastic advocate of chrono-oncology. It illustrates his early dose- and circadian time-response curves, limited as yet by a 4-timepoin...
Cancer chronomics I. Origins of timed cancer treatment: early marker rhythm-guided individualized chronochemotherapy [0.03%]
肿瘤时序组学I. 时间治疗癌症的起源：早期标志物节律指导的个性化定时化学疗法
Franz Halberg,Konald Prem,Francine Halberg et al.
Franz Halberg et al.
A 21-year old patient who presented in 1973 with a rare and highly malignant ovarian endodermal sinus tumor with spillage into the peritoneal cavity is alive and well today after receiving chronochemotherapy. During the first four courses o...
Case Reports
Journal of experimental therapeutics & oncology. 2006;6(1):55-61. DOI: 2006
Genome-wide cDNA microarray screening of genes related to the benefits of paclitaxel and irinotecan chemotherapy in patients with advanced non-small cell lung cancer [0.03%]
吉西他滨联合顺铂治疗对晚期非小细胞肺癌患者疗效相关基因的全基因组cdna微阵列筛选研究
Fumihiro Oshita,Akiko Sekiyama,Haruhiro Saito et al.
Fumihiro Oshita et al.
Previous studies have demonstrated that not only the benefits but also the toxicities of chemotherapy can be predicted by cDNA microarray analysis of tumor specimens obtained before chemotherapy against non-small cell lung cancer (NSCLC). W...