Prognostic factors of germ cell and sex cord-stromal ovarian tumors in pediatric age: 5 years experience [0.03%]
儿童年龄层卵巢生殖细胞肿瘤和性索-间质肿瘤预后因素：5年经验总结
Rasha Elashry,Reda Hemida,Hosam Goda et al.
Rasha Elashry et al.
Background: Ovarian tumors in the pediatric age group are not infrequent. Germ-cell tumors are the commonest ovarian neoplasm in the first two decades of life. Sex cord-stromal tumors are the most common ovarian tumors to...
Induction of apoptosis in hormone refractory breast cancer: horizontal modulation is superior to vertical [0.03%]
激素难治性乳腺癌的诱导凋亡：水平调节优于垂直调节
Wei Yue,Ji-Ping Wang,Ling Zhang et al.
Wei Yue et al.
Women with estrogen receptor positive (ER+) breast cancer receive treatment with tamoxifen or aromatase inhibitors as adjuvant hormone therapy, but their tumors frequently exhibit de novo or acquired resistance. Current strategies being dev...
Agreement of histopathological findings of preoperative uterine curettage and hysterectomy specimens: impact of time factor and hormonal therapy [0.03%]
刮宫与子宫全切标本的病理一致性及其影响因素分析
Reda A Hemida,Abd Elhady Zayed,Asem Shalaby et al.
Reda A Hemida et al.
Objectives: To study the agreement of preoperative curettage and definitive histology after hysterectomy as well as the correlation of time factor and hormonal therapy to this agreement. ...
A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis [0.03%]
一种针对Stat3的SH2结构域的磷肽拟肽前药可抑制肿瘤生长和血管生成
Edmond J Auzenne,Jim Klostergaard,Pijus K Mandal et al.
Edmond J Auzenne et al.
Signal transducer and activator of transcription 3 (Stat3) is constitutively activated in a number of human cancers and cancer cell lines. Via its Src homology 2 (SH2) domain, Stat3 is recruited to phosphotyrosine residues on intracellular ...
PKI 166 induced redox signalling and apoptosis through activation of p53, MAP kinase and caspase pathway in epidermoid carcinoma [0.03%]
PKI-166通过激活p53、MAP激酶和半胱天冬酶途径诱导表皮样癌的氧化还原信号传导和细胞凋亡
Subhasis Das,Kaushik Kumar Dey,Rashmi Bharti et al.
Subhasis Das et al.
Cellular redox changes have emerged as a pivotal and proximal event in cancer. PKI 166 is used to determine the effects of redox sensitive inhibition of EGFR, metastasis and apoptosis in epidermoid carcinoma. Cytotoxicity study of PKI 166 (...
Embryonal rhabdomyosarcoma of the female genital tract: 5 years' experience [0.03%]
女性生殖道胚胎性横纹肌肉瘤五年的临床经验总结
Reda Hemida,Hosam Goda,El-Said Abdel-Hady et al.
Reda Hemida et al.
Objectives: To present our single institution experience with 10 cases of embryonal rhabdomyosarcoma diagnosed over 5 years. Methods: R...
Discovery and development of anticancer agents from marine sponges: perspectives based on a chemistry-experimental therapeutics collaborative program [0.03%]
基于化学-实验治疗协作项目的海洋海绵抗肿瘤药物的发现与开发展望
Frederick A Valeriote,Karen Tenney,Joseph Media et al.
Frederick A Valeriote et al.
A collaborative program was initiated in 1990 between the natural product chemistry laboratory of Dr. Phillip Crews at the University of California Santa Cruz and the experimental therapeutics laboratory of Dr. Fred Valeriote at the Henry F...
Achuta K Guddati
Achuta K Guddati
Current modalities of cancer therapy utilize different agents to block key steps involved in cell division. Newer agents also block specific parts of molecular pathways that are vital for survival of the cancer cells but cells may develop r...
Laleh Karimzadeh,Fariba Koohdani,Fereydoon Siassi et al.
Laleh Karimzadeh et al.
Nitrites, a probable human carcinogen, generate reactive nitrogen species that may cause damage to the lung. We evaluated the association between nutritional habits related to nitrite and nitrate intake and risk of lung cancer in Mazandaran...
Comparative Study
Journal of experimental therapeutics & oncology. 2012;10(2):107-12. DOI: 2012