A Japanese Case of Familial Hypercholesterolemia with a Protein-truncating Variant in LDLR and a PCSK9 Variant without Significant Atherosclerosis but Showing Remarkable Achilles Tendon Thickening [0.03%]
一个日本家族性高胆固醇血症病例，该患者LDLR基因存在截断变异和PCSK9基因存在变异，但没有明显的动脉粥样硬化却足跟腱增厚明显
Takuya Minamizuka,Junji Kobayashi,Hayato Tada et al.
Takuya Minamizuka et al.
The patient was a 54-year-old woman with familial hypercholesterolemia and remarkable Achilles tendon thickening. At 20 years old, the patient had a total cholesterol level of approximately 300 mg/dL. She started receiving rosuvastatin (5 m...
A Japanese Woman with Polygenic Familial Hypercholesteremia Who Exhibited Trivial Atherosclerosis [0.03%]
一位多基因家族性高胆固醇血症的日本女性，动脉粥样硬化病变轻微
Masao Saotome,Yuichiro Maekawa
Masao Saotome
A Case of Gastric Leiomyosarcoma Completely Resected by Endoscopic Submucosal Dissection after a Precise Preoperative Diagnosis [0.03%]
内镜粘膜下挖除术成功切除胃平滑肌肉瘤一例临床病理报告
Kazuma Yachi,Waku Hatta,Tomoyuki Koike et al.
Kazuma Yachi et al.
A 68-year-old woman was diagnosed with leiomyosarcoma (LMS) based on preoperative biopsy of the gastric body. As tumor invasion confined to the submucosa with no breaking of the submucosal layer was confirmed on endoscopic ultrasonography (...
Eosinophilic Gastroenteritis with Ascites, Elevated Serum IgG4, and Hypereosinophilic Syndrome: A Manifestation of IgG4-related Disease? [0.03%]
与IgG4升高和持续嗜酸细胞性综合征相关的腹水性嗜酸细胞性胃肠炎：IgG4相关性疾病的表现形式？
Takao Nagashima,Hiroki Yabe,Naota Okabe et al.
Takao Nagashima et al.
A 76-year-old woman with persistent diarrhea was referred to our hospital. She had purpura, peripheral eosinophilia (18,177/μL), and an elevated serum IgG4 level (819 mg/dL). Abdominal computed tomography revealed massive ascites and bowel...
Precision Trigger Point Injections: An Anatomically Guided Approach for Anterior Cutaneous Nerve Entrapment Syndrome Treatment [0.03%]
精确的触发点注射：治疗前锯肌神经卡压综合征的解剖学指导方法
Takashi Watari,Yuki Otsuka,Yoshihiko Shiraishi
Takashi Watari
A Novel De Novo Variant in KCNH5 in a Patient with Refractory Epileptic Encephalopathy [0.03%]
KCNH5的新发变异导致难治性癫痫性脑病一例报告
Akihiko Mitsutake,Takashi Matsukawa,Tatsuhiko Naito et al.
Akihiko Mitsutake et al.
We herein report a novel de novo KCNH5 variant in a patient with refractory epileptic encephalopathy. The patient exhibited seizures at 1 year and 7 months old, which gradually worsened, leading to a bedridden status. Brain magnetic resonan...
Taichi Nomura,Ikuko Iwata,Katsuki Eguchi et al.
Taichi Nomura et al.
POEMS syndrome is often associated with a poor prognosis. Elevated serum vascular endothelial growth factor (sVEGF) is a useful diagnostic marker with high sensitivity and specificity. However, the relationship between sVEGF elevation and p...
Prognostic Factors of In-hospital Mortality in Patients without Human Immunodeficiency Virus Infection with Pneumocystis Pneumonia: A Retrospective Cohort Study [0.03%]
无艾滋病病毒感染的肺炎球菌肺炎患者的院内死亡预后因素：回顾性队列研究
Jumpei Taniguchi,Shotaro Aso,Taisuke Jo et al.
Jumpei Taniguchi et al.
Objective This study explored the prognostic factors of in-hospital mortality in patients with Pneumocystis pneumonia (PCP) without human immunodeficiency virus (HIV) infection, using a Japanese nationwide inpatient database. Methods We ext...
Exercise-associated Hyponatremia Developing Immediately after a Musical Stage Performance in a Healthy Actress [0.03%]
一名健康女演员在音乐剧表演后立即发生运动性低钠血症病例报告
Moeko Kubo,Ichiro Horie,Jun-Ichi Tokumitsu et al.
Moeko Kubo et al.
Exercise-associated hyponatremia (EAH) is a life-threatening dilutional hyponatremia that typically occurs during or immediately after exercise in endurance athletes. A 49-year-old actress experienced dizziness 15 min after a 2-h stage perf...
Severe Duodenal Bleeding with Heterotaxy Syndrome Controlled by Combined Hemostatic Strategies: A Case Report [0.03%]
异位症伴严重十二指肠出血采用联合止血策略治疗1例报告
Daichi Yomogida,Hiroyuki Kuwano,Tatsuya Miyakoshi et al.
Daichi Yomogida et al.
A 73-year-old man with a history of heterotaxy syndrome and intestinal malrotation developed hemorrhagic shock due to bleeding from a duodenal ulcer. Esophagogastroduodenoscopy failed to achieve hemostasis because of restriction of the view...