Spontaneous Ca2+ oscillations via purinergic receptors elicit transient cell swelling in rat parotid ducts [0.03%]
大鼠腮腺导管中的嘌呤受体介导的钙振荡引起瞬时细胞肿胀
Akiko Shitara,Akihiko Tanimura,Atsuko Sato et al.
Akiko Shitara et al.
Rat parotid ductal cells were found to exhibit spontaneous Ca(2+) oscillations. These oscillatory Ca(2+) responses were observed during continuous perfusion with physiological salt solution at 37 degrees C in the absence of calcium mobilizi...
Ca2+ mobilization by nicotine through synaptic activation in rat parotid acini [0.03%]
尼古丁通过突触激活诱导大鼠腮腺小叶细胞内钙动员
Taichi Iida,Kentaro Ono,Tomohiro Inagaki et al.
Taichi Iida et al.
Nicotine has been reported to increase the intracellular Ca(2+) concentration ([Ca(2+)](i)) in sublingual acini due to neurotransmitter release from nerve terminals associated with the cell preparation (1). However, it is unclear whether or...
Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts [0.03%]
毛果芸香碱和西维美林对大鼠腮腺腺泡和导管细胞内钙动员的影响
Kentaro Ono,Tomohiro Inagaki,Taichi Iida et al.
Kentaro Ono et al.
Previous reports suggested that there is no significant difference in the binding affinity of pilocarpine and cevimeline on muscarinic receptors (1). However, in vivo studies from our laboratory suggested that pilocarpine-induced salivation...
Douglas L Bovell,Barbara Kofler,Roland Lang
Douglas L Bovell
Serine proteases can induce cell signaling by stimulating G-protein-coupled receptors, called proteinase-activated receptors (PAR's) on a variety of epithelial cells. While PAR-2, one such receptor, activates cell signaling in a secretory c...
Role of protein kinase C-delta in isoproterenol-induced amylase release in rat parotid acinar cells [0.03%]
蛋白激酶C-δ在异丙肾上腺素诱导的大鼠腮腺腺细胞淀粉酶释放中的作用
Hiroshi Sugiya,Keitaro Satoh,Miwako Matsuki-Fukushima et al.
Hiroshi Sugiya et al.
In parotid acinar cells, beta-adrenergic receptor activation results in accumulation of intracellular cAMP. Subsequently, cAMP-dependent protein kinase (PKA) is activated and consequently amylase release is provoked. In this paper, we inves...
Regulation of calcium entry in exocrine gland cells and other epithelial cells [0.03%]
外分泌腺细胞和其他上皮细胞中钙流入的调节
James W Putney,Gary S Bird
James W Putney
Monitoring of IP3 dynamics during Ca2+ oscillations in HSY human parotid cell line with FRET-based IP3 biosensors [0.03%]
基于FRET的IP3生物传感器在HSY人腮腺细胞系Ca2+振荡期间监测IP3动力学行为
Akihiko Tanimura,Takao Morita,Akihiro Nezu et al.
Akihiko Tanimura et al.
Inositol 1,4,5-trisphosphate (IP(3)) is an intracellular messenger that elicits a wide range of spatial and temporal Ca(2+) signals, and this signaling versatility is exploited to regulate diverse cellular responses. In the present study, w...
Ivana Novak,Kristian A Haanes,Mette R Hansen et al.
Ivana Novak et al.
Mikio Hayashi,Hiroko Matsuda
Mikio Hayashi
The ductal system of the exocrine pancreas produces HCO(3)(-)-rich fluid in response to secretin and other stimuli. HCO(3)(-) efflux across the luminal membrane is mediated by a Cl(-)-HCO(3)(-) exchanger operating in parallel with the cysti...
Correlation between salivary secretion and salivary AQP5 levels in health and disease [0.03%]
健康与疾病状态下的唾液分泌和唾液AQP5水平的相关性研究
Di Wang,Fusako Iwata,Masahiro Muraguchi et al.
Di Wang et al.
Saliva samples are useful for noninvasive diagnosis of oral and systemic diseases. The water channel protein aquaporin-5 (AQP5) is released into human saliva. Salivary AQP5 levels show a diurnal variation with the secretion of high levels d...