Exosomal MiR-223-3p from Adipose-Derived Stem Cells Alleviates Hypoxia/Reoxygenation-Induced Ferroptosis of H9c2 Cells by Inhibiting TFRC [0.03%]
脂肪来源干细胞衍生的外泌体miR-223-3p通过抑制TFRC缓解H9c2细胞低氧/复氧诱导的铁死亡
Zhuyuan Liu,Yanru He,Chunshu Hao
Zhuyuan Liu
Myocardial ischemia-reperfusion injury (MI/RI) refers to the deterioration of cardiac function after restoring ischemic myocardium perfusion. Stem cell exosomes have produced unique advantages in treating MI/RI. However, the roles of exosom...
Dampened Reactive Hematopoiesis and Systemic Inflammatory Response Following Early Recurrent Myocardial Infarction in Mice [0.03%]
小鼠早期反复心肌梗死后造血功能及全身炎症反应的变化
Yunhang Zhang,Haiju He,Xue Li et al.
Yunhang Zhang et al.
Acute myocardial infarction (AMI) impacts the regenerative capacity of hematopoietic stem and progenitor cells (HSPCs) following injury, but it remains unclear if these functional alterations persist beyond the initial ischemic event.A mini...
Exploring the Role and Mechanism of DSF in HFpEF Based on IL-1β/IL-1βR/TAK1/RIPK1 Axis-Mediated PANoptosis [0.03%]
基于IL-1β/IL-1βR/TAK1/RIPK1轴介导的PANoptosis探讨DSF在HFpEF中的作用及机制研究
Weidong Li,Xuanyang Shen,Xiaolu Jiang et al.
Weidong Li et al.
Heart failure with preserved ejection fraction (HFpEF) has a high prevalence and a low quality of life, and there are limited medications for the treatment of this disease. In recent years, disulfiram (DSF), an FDA-approved drug for the tre...
Validity of Diagnoses of Aortic Dissection and Pulmonary Embolism in Hospitalized Patients Using the Japanese DPC Database [0.03%]
基于日本DPC数据库的主动脉夹层和肺栓塞住院患者的诊断准确性研究
Risa Kishikawa,Satoshi Kodera,Kohei Abe et al.
Risa Kishikawa et al.
Acute aortic dissection (AD) and pulmonary thromboembolism (PE) are life-threatening conditions requiring timely diagnosis. In Japan, large-scale validation studies of administrative data for these diagnoses are limited. It is required to v...
Yuanguo Chen,Shixi Luo,Jing Li et al.
Yuanguo Chen et al.
Hypertrophic cardiomyopathy (HCM), recognized as the most prevalent inherited heart condition, is found in about 0.2% to 0.5% of the population globally. Recent years have witnessed a notable surge in HCM-related scholarly investigations. T...
The Association between Hematocrit and All-Cause Mortality in Patients with Acute Congestive Heart Failure [0.03%]
急性充血性心力衰竭患者血液浓度与全因死亡率之间的关系
Xiaotian Ren,Ye Zhu,Wenyuan Wang et al.
Xiaotian Ren et al.
Hematocrit (HCT) has clinical significance in the prognosis of acute heart failure (AHF). This study investigated the association between HCT and 365-day all-cause mortality rate from the MIMIC-IV database. We also explored the specific inf...
Impact of Preoperative Diuretics Treatment on Long-Term Clinical Outcomes After Transcatheter Aortic Valve Implantation [0.03%]
术前利尿剂治疗对经导管主动脉瓣植入长期临床结局的影响
Shun Hirosawa,Hiroaki Yokoyama,Ken Yamazaki et al.
Shun Hirosawa et al.
Diuretics are used to relieve congestive symptoms in patients with severe aortic stenosis (AS). However, the effect of preprocedural diuretic treatment on long-term outcomes in AS patients who undergoing transcatheter aortic valve implantat...
Multicenter Study
International heart journal. 2026;67(1):27-34. DOI:10.1536/ihj.25-359 2026
Masamichi Yano,Yasuyuki Egami,Noriyuki Kobayashi et al.
Masamichi Yano et al.
Low BMI has been reported to be associated with atrial fibrillation (AF) recurrence post-ablation, as well as with cardiovascular events and mortality. However, the previous studies have not fully accounted for baseline factors including ag...
MicroRNA-21 as a Potential Contributor to Cardiac Diastolic Dysfunction in Hypertensive Patients [0.03%]
高血压患者中微小核糖核酸-21对心室舒张功能障碍的潜在作用研究
Shiori Nishinosono,Tsukuru Umemura,Yoshitaka Hirooka
Shiori Nishinosono