TIF1β Promotes Myocardial Ischemia-Reperfusion Injury by Stabilizing TRAF6 through Mediating TRAF6 SUMOylation [0.03%]
TIF1β通过介导TRAF6的SUMO化来稳定TRAF6,从而促进心肌缺血再灌注损伤
Yue Nan,Xu Zhang,Xinping Du et al.
Yue Nan et al.
Myocardial ischemia-reperfusion injury (MIRI) exacerbates myocardial damage, resulting in a further decline in heart function. Abnormally high TRAF6 expression was reported in MIRI. However, what actually causes the abnormally elevated expr...
Finerenone Attenuates Myocardial Fibrosis and Pyroptosis in Rats with Myocardial Infarction [0.03%]
芬伦诺酮抑制心肌梗死大鼠心肌纤维化和焦亡作用机制研究
Jing Wen,Yan-Chun Ou,Hong-Hong Ke et al.
Jing Wen et al.
The mineralocorticoid receptor (MR) plays a pivotal role in cardiovascular diseases, and its overactivation contributes to heart failure (HF) progression. Finerenone (FIN), a novel nonsteroidal MR antagonist (MRA), shows promise in managing...
Efficacy of Steroid Therapy in Preventing Adverse Clinical Outcomes in Patients with Fulminant Myocarditis Requiring Mechanical Circulatory Support [0.03%]
糖皮质激素治疗在预防需要机械循环支持的急进性心肌炎患者不良临床结局中的有效性的多中心队列研究
Naoki Watanabe,Masashi Kamioka,Daigo Sawaki et al.
Naoki Watanabe et al.
There is limited data about the efficacy of steroid therapy in preventing adverse clinical outcomes in fulminant myocarditis requiring mechanical circulatory support (MCS). This study aimed to evaluate the clinical impact of steroid therapy...
Clinical Impact of Cardiac Arrest in Patients with Fulminant Myocarditis Requiring Veno-Arterial Extracorporeal Membrane Oxygenation [0.03%]
桥接体外膜肺氧合治疗急性暴发性心肌炎心脏骤停的临床意义
Shotaro Komeyama,Toru Kondo,Takahiro Okumura et al.
Shotaro Komeyama et al.
Fulminant myocarditis (FM) is characterized by rapid hemodynamic deterioration and is often accompanied by cardiac arrest (CA). Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is frequently employed to stabilize hemodynamics or ...
Multicenter Study
International heart journal. 2026;67(3):228-237. DOI:10.1536/ihj.25-716 2026
Uric Acid-to-Albumin Ratio Is Associated with Left Ventricular Diastolic Function in Patients with No Significant Perfusion Abnormality [0.03%]
尿酸与白蛋白比率与无明显灌注异常患者左心室舒张功能有关
Takafumi Kawaguchi,Yukihiro Fukuda,Naoya Hironobe et al.
Takafumi Kawaguchi et al.
The ratio of uric acid to albumin is a marker of not only inflammation, but also prognosis of cardiovascular disease. However, whether this ratio is associated with left ventricular (LV) diastolic function remains unknown. This study tested...
Relationship Between the Cumulative Atherogenic Index of Plasma Exposure and Incident Heart Failure [0.03%]
血浆累积致动脉粥样硬化指数与心力衰竭发病之间的关系
Liying Tian,Qi Qi,Xinyu Wu et al.
Liying Tian et al.
We aimed to characterize the relationship between cumulative exposure to atherogenic index of plasma (AIP) and the risk of incident heart failure (HF) in a Chinese population.A total of 57,156 individuals extracted from the Kailuan study da...
Association between Serum Neurofilament Light Chain Levels and the Predicted 10-Year Atherosclerotic Cardiovascular Disease Risk [0.03%]
血清神经丝轻链水平与动脉粥样硬化性心血管疾病10年预期风险的相关性
Mingwei Yang,Huayin Li,Fangchao Wang et al.
Mingwei Yang et al.
This cross-sectional study aimed to examine the association between serum neurofilament light chain (sNfL) and the PCE-estimated 10-year atherosclerotic cardiovascular disease (ASCVD) score using data from the 2013-2014 United States Nation...
Evaluation of Participant Characteristics and Short-Term Outcomes in a Community-Based Hypertension Awareness Event in Japan [0.03%]
日本社区高血压意识活动的参与者特征和短期结果评价
Noriko Taguchi,Satoshi Yanagisawa,Kyoko Tsunekawa et al.
Noriko Taguchi et al.
Percutaneous Coronary Intervention for Coronary Events during Tyrosine Kinase Inhibitor Therapy in Leukemia Patients [0.03%]
酪氨酸激酶抑制剂治疗期间白血病患者冠脉事件的经皮冠状动脉介入治疗
Asaki Saijo,Tetsuo Yamaguchi,Akinori Konishi et al.
Asaki Saijo et al.
Tyrosine kinase inhibitors (TKIs) are essential for treating chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. While cardiovascular risk with TKIs is well recognized, significant coronary artery ste...
Clinical Implications of Myocardial T1 Mapping Parameters in Relation to Left Ventricular Characteristics in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy [0.03%]
野生型甲状腺素转运蛋白心肌病患者心肌T1图参数与左心室特征相关性的临床意义研究
Toshiro Kitagawa,Kotaro Hamamoto,Daiki Okamoto et al.
Toshiro Kitagawa et al.