Esaxerenone Attenuates Atherogenesis and Vascular Dysfunction in Apolipoprotein E-Deficient Mice [0.03%]
雌烯酮通过作用于阿普利卡松E缺陷小鼠减轻动脉粥样硬化和血管功能障碍
Juri Maeda,Uugantsetseg Munkhjargal,Tomoya Hara et al.
Juri Maeda et al.
The pharmacological blockade of mineralocorticoid receptors (MR) is a potential therapeutic approach to reduce cardiovascular complications. Recent studies suggest that MR blockers affect several extrarenal tissues, including vascular funct...
Revisiting the Relationship between Homocysteine, Vitamin B12, Folate, and Aortic Diseases [0.03%]
同型半胱氨酸、维生素B12、叶酸和主动脉疾病之间关系的再评价
Qianlei Lang,Yu Liu,Hongwei Zhang et al.
Qianlei Lang et al.
Although several observational studies have suggested an association between plasma homocysteine (Hcy), vitamin B12, and folate levels and aortic diseases, including aortic dissection (AD), thoracic aortic aneurysm (TAA), and abdominal aort...
Intracardiac Echocardiography-Guided Biopsy for a Giant Cardiac Angiosarcoma with Extensive Invasion [0.03%]
经食道心内超声引导下侵袭性巨大心脏血管肉瘤活检术
Yoshitake Fukuda,Kazufumi Nakamura,Koji Nakagawa et al.
Yoshitake Fukuda et al.
Cardiac angiosarcoma is a rare malignant tumor with a poor prognosis. Because of its aggressive nature, early pathological diagnosis is essential. Previous studies have reported the efficacy of intracardiac echocardiography (ICE) -guided bi...
Case Reports
International heart journal. 2025;66(4):706-711. DOI:10.1536/ihj.25-105 2025
Clinical Observation of Myocardial Contractility Modulation Device in Patients with Chronic Heart Failure [0.03%]
心力衰竭患者心脏收缩力调制装置的临床观察
Hongfei Song,Rui Yang,Wenwei Bai et al.
Hongfei Song et al.
Heart failure (HF) is one of the most common cardiovascular diseases in the 21st century, affecting more than 25 million individuals worldwide. According to estimates, 8.9 million cases have been reported in China alone. Although pharmacoth...
MiR-27b-3p Correlates with Arteriosclerosis Obliterans and Promotes the Proliferation and Migration of Arterial Smooth Muscle Cells by Targeting GAB1 [0.03%]
miR-27b-3p与动脉粥样硬化相关并通过靶向GAB1促进血管平滑肌细胞的增殖和迁移
Tuo Xu,Changwei Zheng,Yongkang Wu et al.
Tuo Xu et al.
Patients with atherosclerosis obliterans (ASO) are at risk of amputation or even death if timely treatment is not provided; current clinical treatments for ASO have certain disadvantages. This study aimed to ascertain the function of miR-27...
MiR-4429 Serves as a Protective Regulator by Targeting GNAI2 in Coronary Artery Disease [0.03%]
MicroRNA-4429通过靶向GNAI2在冠状动脉疾病中起到保护作用
Yu Chen,Siyuan Yang,Yifan Niu et al.
Yu Chen et al.
Increasingly evidence suggests that microRNA (miRNA) plays a pivotal role in coronary artery disease (CAD). This study investigated the abundance of miR-4429 in the serum of CAD patients and explored the function of miR-4429 and its target ...
Transcriptomic Analysis of the Heart Tissue in Spontaneously Hypertensive Rats Exposed to Acute Hypobaric Hypoxia [0.03%]
急性低氧暴露对 SHR 心脏组织转录组的影响及机制研究
Fengzhou Liu,Shiqiang Zhou,Yajuan Li et al.
Fengzhou Liu et al.
We evaluated the effect of acute hypobaric hypoxia (AHH) on the heart of early-stage spontaneously hypertensive male rats (SHRs). The rats were classified into a control (ground level; ~400 m altitude) group and an SHR-AHH experimental grou...
Long Non-Coding RNA NR_027324 Protects H9C2 Cells against Hypoglycemic and Hypoxic Injury by Interacting with microRNA-103-3p [0.03%]
长链非编码RNA NR_027324通过与微小核糖核酸-103-3p结合保护H9C2细胞免受缺糖和缺氧损伤
Qingkun Meng,Chengfu Wang,Yang Gao et al.
Qingkun Meng et al.
This study explored the relationship among lncRNA NR_027324, miR-103-3p, and autophagy-related protein 5 (ATG5) in cardiomyocytes under hypoglycemic/hypoxic conditions.Bioinformatics and luciferase assays were used to investigate the intera...