Microfluidic technologies for protein crystallography: advances and applications [0.03%]
蛋白结晶学的微流体技术：进展与应用
Masatoshi Maeki,Akihiko Ishida,Manabu Tokeshi
Masatoshi Maeki
Three-dimensional protein structure determination by X-ray crystallography is essential for understanding biological function and accelerating drug discovery. However, obtaining high-quality protein crystals remains a significant bottleneck...
Ultra-sensitive biosensor detection of microRNA based on the CRISPR/Cas12a system and exonuclease-assisted target recycling signal amplification [0.03%]
基于CRISPR/Cas12a系统和核酸外切酶介导的目标重复信号放大技术的超灵敏生物传感器检测微小核糖核酸
Xing Yang,Yu Luo,Chunhua Su et al.
Xing Yang et al.
MicroRNAs (miRNAs) are essential regulators of gene expression and are significantly involved in both preventing and treating a range of diseases. To that end, we developed an ultra-sensitive detection method for miRNA-141 by integrating ex...
Raman spectroscopy for the quantitative and qualitative analyses of solid drug formulations of salbutamol [0.03%]
用于定量和定性分析沙丁胺醇固体药物制剂的拉曼光谱法
Syeda Takmeel Zahra,Noor Ul Sabah,Muhammad Irfan Majeed et al.
Syeda Takmeel Zahra et al.
Inhalable drugs are commonly used to treat different kinds of respiratory disorders, such as asthma, coughing, wheezing, and breathing difficulties. Salbutamol is an inhalable drug which is used to treat symptoms of acute obstructive lungs ...
Microfluidic paper-based analytical devices: proven applications and future prospects in therapeutic drug monitoring, homeland security, and chemical education [0.03%]
微流体纸基分析器件在治疗药物监测、国土安全和化学教育中的实际应用及发展前景
Manabu Tokeshi
Manabu Tokeshi
Since the report by Whitesides et al. in 2007 on paper-based microfluidic analytical devices (μPADs), numerous studies have been published. The characteristics of μPADs, such as low cost, simplicity, and suitability for resource-limited s...
Elemental and isotopic analyses of individual nanoparticles using single particle inductively coupled plasma mass spectrometry [0.03%]
采用单颗粒电感耦合等离子体质谱分析纳米粒子的元素和同位素组成
Masaki Nakazato,Takafumi Hirata
Masaki Nakazato
Sensitive and rapid technique for elemental analysis of individual nanoparticles is increasingly desired in various research fields such as geochemical, environmental, clinical, and biochemical sciences. Among the techniques, single particl...
Innovations in paper-based analytical devices and portable absorption photometers for onsite analysis [0.03%]
基于纸的现场分析装置及便携式吸收光度计的新进展
Sasikarn Seetasang,Mika I Umeda,Jianchao Ren et al.
Sasikarn Seetasang et al.
Two types of analytical instruments and devices-one sophisticated high-performance instrument and another portable device-have been the focus of recent trends in analytical science. The necessity of point-of-care testing and onsite analysis...
Breath biomarkers for esophageal cancer: identification, quantification, and diagnostic modeling [0.03%]
食管癌呼吸生物标志物的识别、定量及诊断模型研究
Yuke Ren,Fei Wang,Ziyi Zhu et al.
Yuke Ren et al.
Esophageal cancer is a major global health issue with a high mortality rate. Early diagnosis is crucial for improving patient outcomes, but traditional diagnostic methods are often invasive and costly. This study explores the potential of e...
Confocal micro-X-ray fluorescence and total reflection X-ray fluorescence analyses of Ryugu sample in a laboratory environment [0.03%]
实验室环境下对小行星龙宫样品进行共焦微束X射线荧光和全反射X射线荧光分析
Tsugufumi Matsuyama,Sora Yasuda,Koen Janssens et al.
Tsugufumi Matsuyama et al.
This study analyzed Ryugu samples utilizing confocal micro-X-ray fluorescence (CM-XRF) and total reflection X-ray fluorescence (TXRF), in which information of elemental mapping as well as the content of trace elements could be obtained sepa...
Rapid determination of total colony counts and prediction of shelf life of dried tofu using LF-NMR [0.03%]
采用低场核磁共振技术快速检测冻豆腐菌落总数及预测其货架期
Jian Xiao,Alin Xia,Taidong Hou
Jian Xiao
Dried tofu is a type of bean food that is popular among Chinese people. However, because dried tofu is usually exposed to air during storage or shelf life, this may lead to a rapid increase in colony counts and spoilage, resulting in shorte...
Photothermal radiometric image identification of microplastics through near-infrared excitation [0.03%]
近红外激发的微塑料光热辐射计量图像识别研究
Takumi Aramaki,Miki Isoda,Akira Harata
Takumi Aramaki
Near-infrared excitation photothermal radiometric image identification is demonstrated as a rapid analysis tool for visualizing different types of microplastics (MPs). The excitation wavelengths used for four types of plastic materials, pol...