A dual-antibody sandwich immunoassay using upconversion nanoparticles and magnetic beads for fibrinogen detection [0.03%]
一种用于纤维蛋白原检测的上转换纳米粒子和磁性微球双重抗体夹心免疫分析法
Ke Lv,Weitao Wang,Li Zhang et al.
Ke Lv et al.
Fibrinogen is a vital biomarker for coagulation disorders, with reduced levels increasing bleeding risk and mortality, requiring rapid detection for early diagnosis. Enzyme-linked immunosorbent assay (ELISA) is commonly employed in clinical...
An ultrasensitive sensing strategy based on CRISPR/Cas13a and T7 RNA polymerase amplification for detection of extracellular vesicles [0.03%]
基于CRISPR/Cas13a和T7 RNA聚合酶扩增的超灵敏检测外泌体的新方法
Fengying Ran,Huimin Huang,Bing Shang et al.
Fengying Ran et al.
Extracellular vesicles (EVs) are important biomarkers for an early diagnosis of lung cancer. Herein, we proposed an ultrasensitive fluorescent sensing platform for EVs detection, which involves aptamer and streptavidin-modified magnetic nan...
A cascade signal amplification strategy for the ultrasensitive fluorescence detection of kanamycin base on exonuclease III and mismatched catalytic hairpin assembly [0.03%]
一种基于外切酶Ⅲ和错配催化发夹组装的级联信号放大策略用于超灵敏荧光检测卡那霉素
Zhen Liu,Xing Liu,Qian Wu et al.
Zhen Liu et al.
This study employs a guanine (G)-rich DNA sequence as the recognition element and integrates exonuclease III (Exo III) with a mismatch catalytic hairpin assembly (MCHA)-based cascade isothermal signal amplification strategy to construct a n...
Development of a sensor-compatible vascular microphysiological system for metabolic monitoring during drug-induced endothelial injury [0.03%]
一种用于药物诱导的内皮损伤期间代谢监测的与传感器兼容的血管微生理系统的发展
Yuning Fu,Ryota Okitsu,Yuji Nashimoto et al.
Yuning Fu et al.
Endothelial metabolism is closely linked to vascular function and is often altered in response to pathological stimuli. Although vascular microphysiological systems (MPS) offer a promising in vitro platform for modeling vascular environment...
Satohiro Itagaki,Yojiro Yamamoto,Hiroshi Shiigi
Satohiro Itagaki
Transdermal drug delivery is a useful method to non-invasively deliver drugs from the epidermis to the affected area over the shortest distance using the permeability of the carrier. However, it is essential to design a carrier that can pen...
Progress and prospect: major metabolite analysis of central carbon metabolism with saccharification using mix-mode chromatography-application to multiple parallel fermentation of sake [0.03%]
进展与展望：基于混模色谱的中心碳代谢主要代测分析及在清酒多平行发酵中的应用
Daisuke Kozaki
Daisuke Kozaki
Japanese sake breweries, most of which generally operate as small- and medium-sized companies, use the central carbon metabolism (comprising glycolysis, the tricarboxylic acid cycle, and ethanol fermentation) for producing sake. However, it...
Quantification of nitrate in simulated high-level liquid waste by Raman spectroscopy [0.03%]
拉曼光谱法在模拟高放废液中硝酸根离子定量分析中的应用研究
Qianci Zhang,Qian Liu,Haiqiao Zhu et al.
Qianci Zhang et al.
A rapid analysis technique for determining nitrate in simulated high-level radioactive liquid waste (HLLW) was investigated using Raman spectroscopy. The concentration of nitrate can be quantified by the sharp and strong Raman peak height a...
Development of analytical functions with high-performance liquid phase separation systems on the basis of the moment theory [0.03%]
基于时刻理论的高效液相色谱分析函数的发展研究
Kanji Miyabe
Kanji Miyabe
A theoretical foundation was developed on the basis of a moment theory for investigating in detail the basic principles of separation and analysis functions of high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE)...
The impact of initial cooling rates on cell preservation in frozen water-dimethyl sulfoxide media: a morphological study [0.03%]
初始冷却速率对冻存水-二甲基亚砜体系细胞保存影响的形态学研究
Rinko Sabanai,Yoshifumi Suzuki,Takafumi Mizushige et al.
Rinko Sabanai et al.
We investigated the morphological features of a freeze-concentrated solution (FCS) formed in frozen aqueous dimethyl sulfoxide (DMSO) solutions for cell cryopreservation. Specifically, we investigated the effects of cooling rates and initia...
A green and engineered magnetic ionic liquid system for selective extraction and trace determination of thorium in industrial and environmental samples [0.03%]
一种绿色且适用于工程化磁性离子液体系统的痕量 Thor 铀-selective 提取和测定方法及其在工业和环境样品中的应用
Mehdi Hosseini
Mehdi Hosseini
Thorium contamination poses serious health and environmental risks, highlighting the need reliable detection methods. This study presents a green and engineered analytical system for the selective extraction and determination of thorium ion...