Comprehensive spatial distribution profiling of bioactive emodin in mouse organs using mass spectrometry imaging [0.03%]
基于质谱成像的小鼠器官活性化合物大黄酚的全面空间分布研究
Si-Qi Han,Xiao-Kang Fu,Wei Ha et al.
Si-Qi Han et al.
Emodin is an important anthraquinone compound with good anti-inflammatory activity in Chinese traditional medicine rhubarb. Detailed spatial distribution information in bio-tissues plays an important role in revealing the pharmacodynamics, ...
Determination of hydroquinone in beverages using colorimetric and electrochemical sensors on paper-based device [0.03%]
基于纸基设备的对羟基苯醌比色和电化学传感器测定饮料中的对羟基苯醌
Chanya Punthama,Chim Math,Wijitar Dungchai
Chanya Punthama
Hydroquinone (HQ) is a phenolic compound used in industry processes. We aim to demonstrate a rapid and simple procedure for the determination of HQ. This work has developed two techniques, including colorimetric and electrochemical sensors ...
Impact of hydrophobic modification on biocompatibility of Alaska pollock gelatin microparticles [0.03%]
疏水修饰对白辐鱼明胶微粒生物相容性的影响研究
Ying Chuin Yee,Takeshi Mori,Shima Ito et al.
Ying Chuin Yee et al.
This study investigates the impact of hydrophobic modification on the immunogenicity, cytotoxicity, and inflammatory response of Alaska pollock gelatin (ApGltn) microparticles (MPs). Gelatin, known for its inherent biocompatibility, was mod...
Sustainable approaches to analyzing phenolic compounds: a green chemistry perspective [0.03%]
基于绿色化学的酚类化合物分析方法研究及展望
Rahul Makhija,Pallavi Barik,Ashish Mehta et al.
Rahul Makhija et al.
Innovative and eco-friendly methodologies for the determination of phenolic compounds, showing a paradigm shift in analytical chemistry toward sustainability. Phenolic compounds, valued for their diverse health benefits, have historically b...
Design of deep-red emissive forced intercalation-induced light-up peptide as an indicator for the HIV-1 TAR RNA-ligand assay: integration of benzo[c,d]indole-quinoline (BIQ) cyanine dye into Tat peptide [0.03%]
设计一种深红色发射的强制嵌入诱导发光肽作为HIV-1 TAR RNA-配体测定的指示剂:将苯并[c,d]吲哚-喹啉(BIQ)氰基染料整合到Tat肽中
Akunna Francess Ujuagu,Yusuke Sato,En Ting Tabitha Lee et al.
Akunna Francess Ujuagu et al.
We report on a deep-red emissive fluorogenic peptide probe for human immunodeficiency virus-1 (HIV-1) trans-activation responsive (TAR) RNA as an indicator for fluorescence indicator displacement (FID) assay. The probe design is based on th...
Establishment of an in vitro evaluation method for immunomodulatory functions of yeast strains [0.03%]
用于评价酵母菌株免疫调节功能的体外方法建立
Ying Chuin Yee,Akihiro Nakamura,Yoshikiyo Okada et al.
Ying Chuin Yee et al.
Saccharomyces cerevisiae, a widely studied yeast known for its industrial applications, is increasingly recognized for its potential in immunomodulation. This study aimed to systematically analyze and compare the immune-modulating propertie...
Role of wearable electrochemical biosensors in monitoring renal function biomarkers in sweat: a review [0.03%]
可穿戴式电化学生物传感器在监测汗液肾功能生物标志物中的作用:综述
Ibrahim Luqman Salih,Azad H Alshatteri,Khalid M Omer
Ibrahim Luqman Salih
Real-time detection of renal biomarkers is crucial for immediate and continuous monitoring of kidney function, facilitating early diagnosis and intervention in kidney-related disorders. This proactive approach enables timely adjustments in ...
Development of a HPLC system using a phase-separation multiphase flow as an eluent: an influence of column pressure on phase separation and chromatogram at room temperature [0.03%]
一种使用分相多相流作为流动相的高效液相色谱系统的开发:室温下柱压对分相及色谱图的影响
Keisuke Takagi,Takeshi Iharada,Kazuhiko Tsukagoshi
Keisuke Takagi
We have developed a HPLC system where phase-separation multiphase flow works in the separation column as an eluent. We call the novel separation mechanism a phase-separation mode. The ternary mixed solution of water/acetonitrile/ethyl aceta...
New stability indicating RP-HPLC methods for the determination of related substances and assay of trametinib acetic acid: a mass balance approach [0.03%]
用于评估曲马替尼乙酸盐杂质和测定的新型稳定性表征RP-HPLC方法:一种质量平衡的方法学研究
G Himabindu,Y Satyanarayana Reddy,A V S S Prasad et al.
G Himabindu et al.
New stability indicating related substances and assay methods for trametinib acetic acid by RP-HPLC have been developed and validated through forced degradation and mass balance studies for the first time. In related substances (RS) method,...
In-situ analysis of sub-nanomolar level of Fe(II) in open-ocean waters [0.03%]
开放海洋水中亚纳摩尔浓度Fe(II)的原位分析研究
Hajime Obata,Akira Mase,Toshitaka Gamo et al.
Hajime Obata et al.
Iron (Fe) in seawater is an essential micronutrient for marine phytoplankton, and Fe deficiency limits their growth in high-nutrient, low-chlorophyll areas. The bioavailability of Fe for phytoplankton largely depends on its chemical speciat...