Light-up RNA aptamer-based T-NASBA: a one-pot, label-free strategy for miRNA detection [0.03%]
基于Light-up RNA的T-NASBA技术：一种无需标记的一锅式miRNA检测策略
Yao Fu,Xuejuan Pei,Junhua Cao et al.
Yao Fu et al.
MicroRNAs (miRNAs) are pivotal regulators of cellular processes, with dysregulation linked to diverse diseases, particularly cancer. Current methods, while effective, are often expensive, complex, and require sophisticated equipment. To add...
A conjugated pyridine diimine fluorene-based polymer for the detection of furaltadone [0.03%]
用于检测氟尼辛的共轭吡啶二亚胺芴基聚合物
Lindan Gong,Yan Sun,Hongju Zhang et al.
Lindan Gong et al.
The potential risks posed by antibiotics to human health and the ecological environment have long been a major public concern. Consequently, developing probe technologies capable of efficiently detecting trace levels of antibiotics in envir...
Simultaneous determination of mumefural and citric acid in Japanese apricot fruit juice concentrate using LC with intramolecular excimer-forming derivatization [0.03%]
利用分子内.excimer.形成衍生化的LC同时测定梅花酒浓缩果实汁中的梅酸和柠檬酸
Hideyuki Yoshida,Yuka Imura,Sayaka Minematsu et al.
Hideyuki Yoshida et al.
Mumefural (MF) which is one of the citrate esters with 5-hydoxymethyl-2-furfural is a component of Japanese apricot fruit juice concentrate (plum extract). A selective LC-fluorescence detection method was developed for the simultaneous quan...
Hiroaki Matsumiya
Hiroaki Matsumiya
Direct visualization of phase-separation multiphase flow in a silica bead-packed microchannel using fluorescence microscopy [0.03%]
利用荧光显微镜直接观察硅胶珠填充微通道中的相分离多相流现象
Yuya Yamashiro,Takeshi Iharada,Kazuhiko Tsukagoshi
Yuya Yamashiro
We previously developed a high-performance liquid chromatography (HPLC) system employing phase-separation multiphase flow (PSMF) as the eluent, referred to as the phase-separation mode in HPLC. However, direct visualization of the flow beha...
A dual-antibody sandwich immunoassay using upconversion nanoparticles and magnetic beads for fibrinogen detection [0.03%]
一种用于纤维蛋白原检测的上转换纳米粒子和磁性微球双重抗体夹心免疫分析法
Ke Lv,Weitao Wang,Li Zhang et al.
Ke Lv et al.
Fibrinogen is a vital biomarker for coagulation disorders, with reduced levels increasing bleeding risk and mortality, requiring rapid detection for early diagnosis. Enzyme-linked immunosorbent assay (ELISA) is commonly employed in clinical...
An ultrasensitive sensing strategy based on CRISPR/Cas13a and T7 RNA polymerase amplification for detection of extracellular vesicles [0.03%]
基于CRISPR/Cas13a和T7 RNA聚合酶扩增的超灵敏检测外泌体的新方法
Fengying Ran,Huimin Huang,Bing Shang et al.
Fengying Ran et al.
Extracellular vesicles (EVs) are important biomarkers for an early diagnosis of lung cancer. Herein, we proposed an ultrasensitive fluorescent sensing platform for EVs detection, which involves aptamer and streptavidin-modified magnetic nan...
A cascade signal amplification strategy for the ultrasensitive fluorescence detection of kanamycin base on exonuclease III and mismatched catalytic hairpin assembly [0.03%]
一种基于外切酶Ⅲ和错配催化发夹组装的级联信号放大策略用于超灵敏荧光检测卡那霉素
Zhen Liu,Xing Liu,Qian Wu et al.
Zhen Liu et al.
This study employs a guanine (G)-rich DNA sequence as the recognition element and integrates exonuclease III (Exo III) with a mismatch catalytic hairpin assembly (MCHA)-based cascade isothermal signal amplification strategy to construct a n...
Development of a sensor-compatible vascular microphysiological system for metabolic monitoring during drug-induced endothelial injury [0.03%]
一种用于药物诱导的内皮损伤期间代谢监测的与传感器兼容的血管微生理系统的发展
Yuning Fu,Ryota Okitsu,Yuji Nashimoto et al.
Yuning Fu et al.
Endothelial metabolism is closely linked to vascular function and is often altered in response to pathological stimuli. Although vascular microphysiological systems (MPS) offer a promising in vitro platform for modeling vascular environment...
Satohiro Itagaki,Yojiro Yamamoto,Hiroshi Shiigi
Satohiro Itagaki
Transdermal drug delivery is a useful method to non-invasively deliver drugs from the epidermis to the affected area over the shortest distance using the permeability of the carrier. However, it is essential to design a carrier that can pen...