Immunohistochemical analysis of CXCR4 expression in fibrohistiocytic tumors [0.03%]
CXCR4在纤维组织细胞肿瘤中的表达分布及其意义免疫组化分析
Seiko Toyozawa,Yuki Yamamoto,Yuko Ishida et al.
Seiko Toyozawa et al.
Functional chemokine receptors are expressed in many malignant tumors. These receptors promote tumor growth and metastasis in response to endogenous chemokines. We analyzed the expression of CXCR4, CCR6 and CCR7 in fibrohistiocytic tumors, ...
Inhibitory effects of anti-VEGF antibody on the growth and angiogenesis of estrogen-induced pituitary prolactinoma in Fischer 344 Rats: animal model of VEGF-targeted therapy for human endocrine tumors [0.03%]
抗血管内皮生长因子抗体对雌激素诱导的大鼠垂体泌乳素瘤生长和新生血管形成的作用：人类内分泌肿瘤的VEGF靶向治疗动物模型研究
Katsuhiro Miyajima,Susumu Takekoshi,Johbu Itoh et al.
Katsuhiro Miyajima et al.
Estrogen-induced pituitary prolactin-producing tumors (PRLoma) in F344 rats express a high level of vascular endothelial growth factor (VEGF) associated with marked angiogenesis and angiectasis. To investigate whether tumor development in E...
Seven kinds of intermediate filament networks in the cytoplasm of polarized cells: structure and function [0.03%]
极化细胞胞浆中间丝网络的七种类型：结构与功能
Hirohiko Iwatsuki,Masumi Suda
Hirohiko Iwatsuki
Intermediate filaments (IFs) are involved in many important physiological functions, such as the distribution of organelles, signal transduction, cell polarity and gene regulation. However, little information exists on the structure of the ...
Potential involvement of the stem cell factor receptor c-kit in alopecia areata and androgenetic alopecia: histopathological, immunohistochemical, and semiquantitative investigations [0.03%]
脱发与干细胞因子受体C-kit的潜在关系：组织病理学、免疫组化及半定量研究
Md Ashrafuzzaman,Tomoko Yamamoto,Noriyuki Shibata et al.
Md Ashrafuzzaman et al.
Alopecia areata (AAR) and androgenetic alopecia (AGA) are two major forms of alopecia based on altered hair growth condition. In general, the cell cycle is regulated by several mechanisms including the stem cell factor/c-kit signaling. To a...
The air liquid-interface, a skin microenvironment, promotes growth of melanoma cells, but not their apoptosis and invasion, through activation of mitogen-activated protein kinase [0.03%]
空气液界面通过激活丝裂原活化蛋白激酶促进黑色素瘤细胞生长，但不促使其凋亡和侵袭
Chong Hong Yee,Shigehisa Aoki,Kazuyoshi Uchihashi et al.
Chong Hong Yee et al.
The air-liquid interface (ALI) is a common microenvironment of the skin, but it is unknown whether the ALI affects melanoma cell behaviors. Using a collagen gel invasion assay, immunohistochemistry, and Western blots, here we show that mela...
The expression of Wnt4 is regulated by estrogen via an estrogen receptor alpha-dependent pathway in rat pituitary growth hormone-producing cells [0.03%]
雌激素通过依赖雌激素受体α的途径调节大鼠垂体生长激素产生细胞中Wnt4的表达
Takashi Miyakoshi,Hanako Kajiya,Katsuhiro Miyajima et al.
Takashi Miyakoshi et al.
Wnt signaling is important in many aspects of cell biology and development. In the mouse female reproductive tract, Wnt4, Wnt5a, and Wnt7a show differential expression during the estrus cycle, suggesting that they participate in female repr...
Immunohistochemical detection of 13(R)-hydroxyoctadecadienoic acid in atherosclerotic plaques of human carotid arteries using a novel specific antibody [0.03%]
新型特异性抗体在人颈动脉粥样硬化斑块中检测13(R)-羟基十八二烯酸的免疫组化定位研究
Noriyuki Shibata,Sono Toi,Takahiro Shibata et al.
Noriyuki Shibata et al.
13-Hydroxyoctadecadienoic acid (13-HODE) is a major component of oxidized low density lipoprotein (OxLDL), which has been shown to have a crucial role in atherogenesis. Of the 13-HODE stereoisomers, 13(S)-HODE and 13(R)-HODE, little is know...
Expression of cysLT1 and cysLT2 receptor in chronic hyperplastic eosinophilic sinusitis [0.03%]
慢性增生性嗜酸细胞性鼻窦炎中胱硫醚- LTD1和LTD2受体的表达
Yuhui Ouyang,Atsushi Kamijo,Shin-ichi Murata et al.
Yuhui Ouyang et al.
Elevated production of cysteinyl leukotrienes (cysLTs) from sinus tissues and abundant sinus eosinophils are characteristic features of chronic hyperplastic eosinophilic sinusitis (CHS). CysLTs exert their action through G-protein-coupled r...
Human papillomavirus infection and its possible correlation with p63 expression in cervical cancer in Japan, Mongolia, and Myanmar [0.03%]
人乳头瘤病毒感染及其与日本、蒙古和缅甸宫颈癌中p63表达的可能关联
Ulziibat Shirendeb,Yoshitaka Hishikawa,Shingo Moriyama et al.
Ulziibat Shirendeb et al.
Although human papillomavirus (HPV) 16 is the cause of cervical cancer in most countries including Japan, the involvement of cervical cancer with HPV types in Mongolian and Myanmar populations is largely unknown. We examined the expression ...
Application of Fluoro-Jade C in acute and chronic neurodegeneration models: utilities and staining differences [0.03%]
荧光黄素C在急性及慢性神经退行性模型中的应用及其染色差异
Ayuka Ehara,Shuichi Ueda
Ayuka Ehara
Recent neuropathological studies have shown that Fluoro-Jade C (FJC), an anionic fluorescent dye, is a good marker of degenerating neurons. However, those studies have mostly examined acute rather than chronic models of neurodegeneration. W...