Heat shock protein 47: a novel biomarker of phenotypically altered collagen-producing cells [0.03%]
热休克蛋白47：表型改变的胶原产生细胞的新生物标志物
Takashi Taguchi,Arifa Nazneen,Abdulmonem A Al-Shihri et al.
Takashi Taguchi et al.
Heat shock protein 47 (HSP47) is a collagen-specific molecular chaperone that helps the molecular maturation of various types of collagens. A close association between increased expression of HSP47 and the excessive accumulation of collagen...
Prenatal and Lactational Exposure to Bisphenol A in Mice Alters Expression of Genes Involved in Cortical Barrel Development without Morphological Changes [0.03%]
孕鼠和哺乳期暴露于双酚A会改变小鼠皮层 barrels发育相关基因的表达而不引起形态学变化
Longzhe Han,Kyoko Itoh,Takeshi Yaoi et al.
Longzhe Han et al.
It has been reported that premature infants in neonatal intensive care units are exposed to a high rate of bisphenol A (BPA), an endocrine disrupting chemical. Our previous studies demonstrated that corticothalamic projection was disrupted ...
Localization of heat shock protein 27 (hsp27) in the rat gingiva and its changes with tooth eruption [0.03%]
热休克蛋白27在大鼠牙龈的定位及其与牙齿萌出的关系研究
Au Sasaki,Tohru Yamada,Katsuyuki Inoue et al.
Au Sasaki et al.
Heat shock protein 27 kDa (Hsp27) functions as a molecular chaperon to prevent apoptosis as well as to contribute to the regulation of cell proliferation and differentiation during development. In the present study, the localization of Hsp2...
Turnover of synapse and dynamic nature of synaptic molecules in vitro and in vivo [0.03%]
体外和体内突触的周转及突触分子的动态变化性质
Satoru Kondo,Shigeo Okabe
Satoru Kondo
Recent advances of imaging techniques have enabled us to investigate the dynamics of synapses in living neurons. The synapse is constructed of presynaptic and postsynaptic elements which contain various kinds of structural and functional mo...
Mayumi Nishi
Mayumi Nishi
Adrenal corticosteroids (cortisol in humans or corticosterone in rodents) exert numerous effects on the central nervous system that regulates the stress response, mood, learning and memory, and various neuroendocrine functions. Corticostero...
Morihiro Higashi,Jianyong Yu,Hiroshi Tsuchiya et al.
Morihiro Higashi et al.
Rho family G proteins including Rac regulate a variety of cellular functions, such as morphology, motility, and gene expression. Here we developed a fluorescence resonance energy transfer-based analysis in which we could monitor the activit...
Infiltration of T lymphocytes and expression of icam-1 in the hippocampus of patients with hippocampal sclerosis [0.03%]
T淋巴细胞浸润和ICAM-1在海马硬化患者海马组织中的表达
Hiroaki Nakahara,Yoshihiro Konishi,Thomas G Beach et al.
Hiroaki Nakahara et al.
We and others have previously shown that reactive microglia express the major histocompatibility complex (MHC) class I and class II antigens in the hippocampus of patients suffering from epilepsy. Although the MHC glycoproteins serve as res...
Neuropathology does not Correlate with Regional Differences in the Extent of Expansion of CTG Repeats in the Brain with Myotonic Dystrophy Type 1 [0.03%]
神经病理学与CTG重复序列在I型肌萎缩性 dystrophy大脑区域扩张范围的差异无关
Kyoko Itoh,Maki Mitani,Kunihiko Kawamoto et al.
Kyoko Itoh et al.
Myotonic dystrophy (DM1) is known to be an adult-onset muscular dystrophy caused by the expansion of CTG repeats within the 3' untranslated region of the dystrophin myotonin protein kinase (DMPK) gene. The clinical features of DM1 include C...
Expression and Role of the BDNF Receptor-TrkB in Rat Adrenal Gland under Acute Immobilization Stress [0.03%]
急性束缚应激下大鼠肾上腺脑源性神经营养因子及其受体TrkB的表达及作用研究
Yusuke Kondo,Juri Saruta,Masahiro To et al.
Yusuke Kondo et al.
We reported that plasma brain-derived neurotrophic factor (BDNF) was maximally elevated following a 60-min period of acute immobilization stress and that salivary glands were the main source of plasma BDNF under this stress condition. Howev...
Fibulin-4 and -5, but not Fibulin-2, are Associated with Tropoelastin Deposition in Elastin-Producing Cell Culture [0.03%]
纤连蛋白-4和-5而不是纤连蛋白-2与产生弹性蛋白的细胞培养中的弹力蛋白原沉积相关性研究
Yoshinori Yamauchi,Eichi Tsuruga,Kazuki Nakashima et al.
Yoshinori Yamauchi et al.
Elastic system fibers consist of microfibrils and tropoelastin. During development, microfibrils act as a template on which tropoelastin is deposited. Fibrillin-1 is the major component of microfibrils. It is not clear whether elastic fiber...