Takeo Aoki,Takeshi Suzuki,Haruo Hagiwara et al.
Takeo Aoki et al.
Aquaporin 2 (AQP2) is a membrane water channel protein that traffics between the intracellular membrane compartment and the plasma membrane in a vasopressin-dependent manner in the renal collecting duct cell to control the amount of water r...
Immunocytochemical colocalization of fibroblast growth factor-1 with neurotrophin-3 in mouse alveolar macrophages [0.03%]
小鼠肺泡巨噬细胞中成纤维细胞生长因子1与神经营养因子3的免疫细胞化学共定位研究
Hiromi Hiruma,Shiori Hikawa,Tadashi Kawakami
Hiromi Hiruma
Alveolar macrophages are known to express a variety of growth factors and neurotrophins. Fibroblast growth factor-1 (FGF-1) is abundantly present in the lung and has mitogenic and neurotrophic activities similarly to neurotrophins. In order...
A novel mutation of human liver alanine:glyoxylate aminotransferase causes primary hyperoxaluria type 1: immunohistochemical quantification and subcellular distribution [0.03%]
人肝丙氨酸：乙醛酸转氨酶的新变异导致原发性高草酸尿症1型：免疫组化定量和亚细胞分布
Chikage Kawai,Yohsuke Minatogawa,Hidetaka Akiyoshi et al.
Chikage Kawai et al.
A novel alanine:glyoxylate aminotransferase (AGT) mutation involved in primary hyperoxaluria type 1 (PH1) was studied in Japanese patients. Two mutations in exon 7, c.751T>A and c.752G>A, lead to a W251K amino acid substitution. Proband 1 (...
Tiantian Gu,Hongjuan He,Yan Zhang et al.
Tiantian Gu et al.
Mouse Trmt112, the homologous gene of yeast Trm112 (tRNA methyltransferase 11-2), was initially cloned from RIKEN with uncertain function. The yeast TRM112 is now known to play important roles in RNA methylation. Here, we studied the expres...
Histological Observation of Regions around Bone Tunnels after Compression of the Bone Tunnel Wall in Ligament Reconstruction [0.03%]
韧带重建时骨隧道壁受压后的骨隧道周围组织的 histology观察
Shintaro Maeda,Hiroki Ishikawa,Naoaki Tanigawa et al.
Shintaro Maeda et al.
The objectives of this study were to investigate the time-course of influence of compression of bone tunnel wall in ligament reconstruction on tissue around the bone tunnel and to histologically examine the mechanism of preventing the compl...
Development of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma [0.03%]
超灵敏免疫组化技术的发展及其在成人T细胞白血病/淋巴瘤病因学研究中的应用
Kazuhisa Hasui,Jia Wang,Yuetsu Tanaka et al.
Kazuhisa Hasui et al.
Antigen retrieval (AR) and ultra-super sensitive immunohistochemistry (ultra-IHC) have been established for application to archival human pathology specimens. The original ultra-IHC was the ImmunoMax method or the catalyzed signal amplifica...
Gene suppression of mouse testis in vivo using small interfering RNA derived from plasmid vectors [0.03%]
利用质粒载体产生的小干扰RNA在活体中抑制基因表达及功能研究
Takami Takizawa,Tomoko Ishikawa,Takuji Kosuge et al.
Takami Takizawa et al.
We evaluated whether inhibiting gene expression by small interfering RNA (siRNA) can be used for an in vivo model using a germ cell-specific gene (Tex101) as a model target in mouse testis. We generated plasmid-based expression vectors of s...
Temporal and Spatial Cellular Distribution of Neural Crest Derivatives and Alpha Cells during Islet Development [0.03%]
胰岛发育过程中神经嵴衍生物和α细胞的时空调控分布规律研究
Kousuke Shimada,Toshiaki Tachibana,Kei Fujimoto et al.
Kousuke Shimada et al.
Recent studies have revealed that signals from neural crest (NC) derivatives regulate the mass, proliferation, and maturation of beta cells in developing fetal pancreas. However, little is known about the cellular distribution of NC derivat...
Immunohistochemical Mapping of TRK-Fused Gene Products in the Rat Brainstem [0.03%]
大鼠脑干中TRK融合基因产物的免疫组织化学定位
Shigeko Takeuchi,Chiaki Masuda,Hisae Maebayashi et al.
Shigeko Takeuchi et al.
The TRK-fused gene (TFG in human, Tfg in rat) was originally identified in human papillary thyroid cancer as a chimeric form of the NTRK1 gene. It was since reported that the gene product (TFG) plays a role in regulating phosphotyrosine-spe...
Compensatory upregulation of myelin protein zero-like 2 expression in spermatogenic cells in cell adhesion molecule-1-deficient mice [0.03%]
细胞粘附分子-1缺陷型小鼠精原细胞中髓鞘蛋白零样2的表达上调补偿机制研究
Hiroki Nakata,Tomohiko Wakayama,Kannika Adthapanyawanich et al.
Hiroki Nakata et al.
The cell adhesion molecule-1 (Cadm1) is a member of the immunoglobulin superfamily. In the mouse testis, Cadm1 is expressed in the earlier spermatogenic cells up to early pachytene spermatocytes and also in elongated spermatids, but not in ...