Sperm DNA methylation alterations induced by gestational arsenic exposure are established stepwise during spermatogenesis [0.03%]
砷暴露引起的精子DNA甲基化改变在精子发生过程中逐步建立
Takehiro Suzuki,Kazuyuki Okamura,Keiko Nohara
Takehiro Suzuki
Background: Gestational exposure to environmental toxicants has been reported to be associated with epigenetic alterations in the male germ line. We have previously demonstrated that gestational arsenic exposure induces c...
High-throughput, low volume d-ROMs and BAP assays: 384-well plate method for large-scale studies [0.03%]
高通量、低体积的d-ROM和BAP测定法：大规模研究的384孔板方法
Goki Yamada,Sudarma Bogahawaththa,Yuichiro Nishida et al.
Goki Yamada et al.
Background: The d-ROMs and BAP serum tests are promising markers of oxidative balance in research settings. Conventional assay systems require 30 µL of serum and approximately 10 minutes to analyze a single sample. Altho...
Association between ERCC5 gene rs17655 polymorphism and the risk of breast cancer: an updated meta-analysis [0.03%]
ERCC5基因多态性与乳腺癌风险的关联：一项最新meta分析
Wen-Shu Luo,Anqi Shi,Zheng Wang et al.
Wen-Shu Luo et al.
Background: Previously, several studies have focused on the correlation between SNPs of the excision repair cross-complementation group 5 (ERCC5) gene and breast cancer susceptibility, and the rs17655 (Asp1104His) has bee...
COVID-19-related health literacy, general health literacy, and mental health problems: evidence from a population-based study in Japan [0.03%]
与COVID-19相关的健康素养、一般健康素养和精神健康问题——来自日本的一项基于人口的证据
Keiko Murakami,Hideki Hashimoto
Keiko Murakami
Background: The coronavirus disease 2019 (COVID-19) pandemic highlighted poor health literacy (HL) as an underestimated public health problem. This study aimed to examine whether COVID-19-related HL and general HL were di...
LncRNA OIP5-AS1 knockdown is associated with attenuated nonylphenol-induced cardiac fibrosis [0.03%]
OIP5-AS1低表达与非酚酞诱导的心脏纤维化减轻有关
Jie He,Jie Xu,Huawen Yu et al.
Jie He et al.
Background: Environmental endocrine disruptors (EEDs), endocrine-interfering pollutants, attract attention for potentially affecting heart diseases via epigenetics. Nonylphenol (NP), a classical representative of endocrin...
Combined effects of nitrogen dioxide and ozone air pollution on maternal liver function during pregnancy: a birth cohort study in China [0.03%]
中国一项出生队列研究：孕期氮氧化物和臭氧空气污染对母亲肝功能的联合影响
Zhijian Chen,Zhongai Ouyang,Weigui Ni et al.
Zhijian Chen et al.
Background: Nitrogen dioxide (NO2) and ozone (O3) exposure is associated with alterations in liver function, but epidemiological evidence in pregnant women remains limited, especially regarding the combined effects. This ...
BPS and BPF linked to metabolic alterations independent of adiposity in Thai children and adolescents [0.03%]
泰国儿童和青少年中与肥胖无关的BPS和BPF独立与代谢改变相关
Watcharin Netiwuttisan,Ekkachai Nakaviroj,Nattakarn Numsriskulrat et al.
Watcharin Netiwuttisan et al.
Background: Bisphenol A (BPA) and its structural substitutes, bisphenol S (BPS) and bisphenol F (BPF), are widely used endocrine-disrupting chemicals. While BPA exposure has been linked to metabolic disorders, evidence re...
Causes of severe injuries in wheelchair user motor vehicle passengers: pilot study for future safety restraint system [0.03%]
有关轮椅使用者机动车乘客严重受伤原因的试点研究——为将来安全束缚系统的规划而设计
Masahito Hitosugi,Ayumu Kuwahara,Yoshitake Kitaguchi et al.
Masahito Hitosugi et al.
Background: As population aging progresses in Japan, an increasing number of older wheelchair users regularly travel in the rear space of motor vehicles. Poor seatbelt fit is the main cause of severe or fatal injuries in ...
Dynapenic abdominal obesity and elevated risk of multidimensional multimorbidity across physical, psychological, and cognitive domains: evidence from longitudinal cohorts [0.03%]
Dynapenic腹型肥胖与身体、心理和认知维度多维多病患风险升高：纵向队列的证据
Xiqiang Zhang,Chenglu Jiang,Jiaming Li et al.
Xiqiang Zhang et al.
Background: The long-term impact of dynapenic abdominal obesity (D/AO)-the coexistence of muscle weakness and central adiposity-on physical, psychological, and cognitive multidimensional multimorbidity (mMM) remains uncle...
Associations between maternal exposure to per- and polyfluoroalkyl substances and functional constipation in children at 3 and 4 years: the Japan Environment and Children's Study [0.03%]
基于日本环境与儿童研究项目的母体全氟和多氟化合物暴露与幼儿功能性便秘的关联调查
Kohei Hasegawa,Yuji Inaba,Shoji Saito et al.
Kohei Hasegawa et al.
Background: Research over the past decade has indicated that exposure to per- and polyfluoroalkyl substances (PFAS) disrupts the intestinal barrier, potentially contributing to the development of gastrointestinal disorder...