Live imaging of paracrine signaling: Advances in visualization and tracking techniques [0.03%]
旁分泌信号的活体成像：可视化和追踪技术的进步
Eriko Deguchi,Michiyuki Matsuda,Kenta Terai
Eriko Deguchi
Live imaging techniques have revolutionized our understanding of paracrine signaling, a crucial form of cell-to-cell communication in biological processes. This review examines recent advances in visualizing and tracking paracrine factors t...
Tango1L but not Tango1S, Tali and cTAGE5 is required for export of type II collagen in medaka fish [0.03%]
斑马鱼Tango1L而非Tango1S、Tali和cTAGE5参与II型胶原蛋白的跨内质网输出过程
Yusuke Yasuda,Tomoka Yoshida,Mahiro Oue et al.
Yusuke Yasuda et al.
Newly synthesized proteins destined for the secretory pathway are folded and assembled in the endoplasmic reticulum (ER) and then transported to the Golgi apparatus via COPII vesicles, which are normally 60-90 nm. COPII vesicles must accord...
The Role of Primary Cilia in Myoblast Proliferation and Cell Cycle Regulation during Myogenesis [0.03%]
原肌细胞生成过程中初级纤毛在肌管增殖和细胞周期调节中的作用
Zhichao Wu,Nuo Chen,Daisuke Takao
Zhichao Wu
The process of mammalian myogenesis is fundamental to understanding muscle development and holds broad relevance across multiple fields, from developmental biology to regenerative medicine. This review highlights two key aspects: myoblast p...
Impact of physiological ionic strength and crowding on kinesin-1 motility [0.03%]
生理离子强度和拥挤对动力蛋白酶运动的影响
Misaki Sagawa,Kazuhiro Oiwa,Hiroaki Kojima et al.
Misaki Sagawa et al.
The motility of biological molecular motors has typically been analyzed by in vitro reconstitution systems using motors isolated and purified from organs or expressed in cultured cells. The behavior of biomolecular motors within cells has f...
Magnetic control of membrane damage in early endosomes using internalized magnetic nanoparticles [0.03%]
利用内化磁性纳米颗粒在早期胞吞小体中实现膜损伤的磁控制
Yuta Yonekawa,Kazuki Oikawa,Boldbaatar Bayarkhuu et al.
Yuta Yonekawa et al.
Membrane stiffness is essential for cell migration, tumorigenesis, and development; however, the physical properties of intracellular membrane are poorly characterized. In this study, we internalized 20 nm magnetic nanoparticles (MNPs) into...
A sensitive ERK fluorescent probe reveals the significance of minimal EGF-induced transcription [0.03%]
一种灵敏的ERK荧光探针揭示了极少量EGF诱导的转录的意义
Zhang Weisheng,Jun Nakayama,Yukino Inomata et al.
Zhang Weisheng et al.
Extracellular signal-regulated kinase (ERK) regulates multiple cellular functions through distinct activation patterns. Genetically encoded fluorescent probes are instrumental in dissecting the ERK activity dynamics in living cells. Here we...
Multi-color fluorescence live-cell imaging in Dictyostelium discoideum [0.03%]
多重荧光活细胞成像在Dictyostelium discoideum中的应用
Hidenori Hashimura,Satoshi Kuwana,Hibiki Nakagwa et al.
Hidenori Hashimura et al.
The cellular slime mold Dictyostelium discoideum, a member of the Amoebozoa, has been extensively studied in cell and developmental biology. D. discoideum is unique in that they are genetically tractable, with a wealth of data accumulated o...
Possible roles of CAHS proteins from Tardigrade in osmotic stress tolerance in mammalian cells [0.03%]
缓步动物CAHS蛋白可能在哺乳动物细胞渗透胁迫耐受中扮演的作用
Takahiro Bino,Yuhei Goto,Gembu Maryu et al.
Takahiro Bino et al.
Anhydrobiosis, a phenomenon in which organisms survive extreme dehydration by entering a reversible ametabolic state, is a remarkable example of survival strategies. This study focuses on anhydrobiosis in tardigrades, which are known for th...
The expression of the formin Fhod3 in mouse tongue striated muscle [0.03%]
小鼠舌横纹肌formin家族成员Fhod3的表达式异变研究
Hikaru Nakagawa,Yohko Kage,Ayako Miura et al.
Hikaru Nakagawa et al.
The sarcomere is the contractile unit of striated muscle and is composed of actin and myosin filaments. There is increasing evidence to support that actin assembly mediated by Fhod3, a member of the formin family of proteins, is critical fo...
Cell-wide arrangement of Golgi/RE units depends on the microtubule organization [0.03%]
细胞内高尔基体/内质网单位的排列取决于微管的组织方式
Tatsuya Tago,Syara Fujii,Shogo Sasaki et al.
Tatsuya Tago et al.
We have previously shown that Golgi stacks and recycling endosomes (REs) exist as Golgi/RE units in sea urchin embryos. In this study, we showed that Golgi/RE units were scattered throughout the cytoplasm at early developmental stages but g...