Effect of 3-methyladenine on the fusion process of macropinosomes in EGF-stimulated A431 cells [0.03%]
3-甲基腺嘌呤对EGF刺激的A431细胞巨胞饮体融合过程的影响研究
Nobukazu Araki,Masao Hamasaki,Youhei Egami et al.
Nobukazu Araki et al.
In the process of receptor-mediated endocytosis, the fusion of endosomes in vitro is known to be inhibited by wortmannin or LY294002; inhibitors of phosphoinositide 3-kinase (PI3K), suggesting that the activity of PI3K is required for the f...
Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation [0.03%]
糖饥饿诱导的内质网分子 chaperoneBiP 对转录因子ATF6表面二硫键的还原作用
Satomi Nadanaka,Hiderou Yoshida,Kazutoshi Mori
Satomi Nadanaka
Mammalian transcription factor ATF6 is constitutively synthesized as a type II transmembrane protein embedded in the endoplasmic reticulum (ER). Upon ER stress ATF6 is transported to the Golgi apparatus where it is cleaved to release its cy...
Analysis of ATF6 activation in Site-2 protease-deficient Chinese hamster ovary cells [0.03%]
ATF6在无S2P的中国仓鼠卵巢细胞中的活化分析研究
Satomi Nadanaka,Hiderou Yoshida,Ryuichiro Sato et al.
Satomi Nadanaka et al.
Mammalian transcription factor ATF6 is constitutively synthesized as a type II transmembrane protein embedded in the endoplasmic reticulum (ER). It is activated when unfolded proteins are accumulated in the ER under ER stress through a proc...
XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from Site-2 protease-deficient Chinese hamster ovary cells [0.03%]
XBP1对于保护细胞免受内质网应激至关重要：来自Site-2蛋白酶缺陷中国仓鼠卵巢细胞的证据
Hiderou Yoshida,Satomi Nadanaka,Ryuichiro Sato et al.
Hiderou Yoshida et al.
XBP1 is a transcription factor downstream of IRE1, a transmembrane protein in the endoplasmic reticulum (ER) which functions as a sensor and transducer of ER stress. XBP1 mRNA is constitutively expressed at a low level as an intron-containi...
Mechanical strength of sarcomere structures of skeletal myofibrils studied by submicromanipulation [0.03%]
微操作研究骨骼肌原纤维肌节结构的机械强度
Taisuke Kayamori,Norihito Miyake,Nao Akiyama et al.
Taisuke Kayamori et al.
The mechanical strength of sarcomere structures of skeletal muscle was studied by rupturing single myofibrils of rabbit psoas muscle by submicromanipulation techniques. Microbeads coated with alpha-actinin were attached to the surface of my...
Visualization of the post-Golgi trafficking of multiphoton photoactivated transferrin receptors [0.03%]
用于多光子激活的转铁蛋白受体的转运后高尔基体可视化技术
Hong Luo,Fubito Nakatsu,Akiko Furuno et al.
Hong Luo et al.
Newly synthesized membrane proteins are sorted in the trans-Golgi network (TGN) on the basis of sorting signals carried in their cytoplasmic domains and delivered to their final destinations in the secretory and endocytic pathways. Although...
Soluble megalin is accumulated in the lumen of the rat endolymphatic sac [0.03%]
可溶性巨大elin在大鼠内淋巴囊腔的积累
Tetsuya Ishida,Tanenori Hatae,Nozomu Nishi et al.
Tetsuya Ishida et al.
The endolymphatic sac (ES) is believed to play an important role in maintaining homeostasis in the inner ear by the absorption and endocytosis of endolymph. Megalin is a 600-kDa multiligand endocytic receptor expressed in certain types of a...
The functional relationship between the Cdc50p-Drs2p putative aminophospholipid translocase and the Arf GAP Gcs1p in vesicle formation in the retrieval pathway from yeast early endosomes to the TGN [0.03%]
CDC50P-DRS2p假定的氨基磷脂转换酶与GCS1p在从酵母早期内体到TGN回收途径囊泡形成中的功能关系
Hiroshi Sakane,Takaharu Yamamoto,Kazuma Tanaka
Hiroshi Sakane
Drs2p, the catalytic subunit of the Cdc50p-Drs2p putative aminophospholipid translocase, has been implicated in conjunction with the Arf1 signaling pathway in the formation of clathrin-coated vesicles (CCVs) from the TGN. Herein, we searche...
Identification of Jmjd1a as a STAT3 downstream gene in mES cells [0.03%]
在小鼠胚胎干细胞中鉴定出Jmjd1a是STAT3的下游基因
Song Yi Ko,Hye Yoon Kang,Hyun Sil Lee et al.
Song Yi Ko et al.
Mouse embryonic stem (mES) cells can be maintained in undifferentiated state in the presence of a cytokine, leukemia inhibitory factor (LIF). Many investigators found that STAT3 activation is important for the maintenance of pluripotency by...
X-ray irradiation altered chemosensitivity of a p53-null non-small cell lung cancer cell line [0.03%]
X射线辐照改变了p53缺失的非小细胞肺癌细胞系的化学敏感性
Kaori Tsutsumi,Motoaki Yasuda,Takeshi Nishioka
Kaori Tsutsumi
Radiotherapy is an effective approach to treating many types of cancer. Recent progress in radiotherapy technology, such as intensity-modulated radiation therapy (IMRT) and three-dimensional (3D) radiotherapy, allow precise energy transfer ...
Comparative Study
Cell structure and function. 2006;31(2):47-52. DOI:10.1247/csf.31.47 2006