SPIRAL2 Stabilises Endoplasmic Microtubule Minus Ends in the Moss Physcomitrella patens [0.03%]
螺旋2稳定了苔类植物Physcomitrella patens中的内质网微管负端
Shu Yao Leong,Moé Yamada,Naoki Yanagisawa et al.
Shu Yao Leong et al.
Stabilisation of minus ends of microtubules (MTs) is critical for organising MT networks in land plant cells, in which all MTs are nucleated independent of centrosomes. Recently, Arabidopsis SPIRAL2 (SPR2) protein was shown to localise to p...
A Missense Mutation in the NSF Gene Causes Abnormal Golgi Morphology in Arabidopsis thaliana [0.03%]
拟南芥NSF基因错义突变导致高尔基体形态异常
Sayuri Tanabashi,Keiko Shoda,Chieko Saito et al.
Sayuri Tanabashi et al.
The Golgi apparatus is a key station of glycosylation and membrane traffic. It consists of stacked cisternae in most eukaryotes. However, the mechanisms how the Golgi stacks are formed and maintained are still obscure. The model plant Arabi...
Intestinal Epithelial Cell-specific Deletion of α-Mannosidase II Ameliorates Experimental Colitis [0.03%]
肠上皮细胞特异性删除α-甘露糖苷酶II改善实验性结肠炎
Koichiro Suzuki,Takahiro Yamada,Keiko Yamazaki et al.
Koichiro Suzuki et al.
Inflammatory bowel disease (IBD) is a refractory disease of the gastrointestinal tract that is believed to develop in genetically susceptible individuals. Glycosylation, a type of post-translational modification, is involved in the developm...
Flagellar-associated Protein FAP85 Is a Microtubule Inner Protein That Stabilizes Microtubules [0.03%]
鞭毛相关蛋白FAP85是一种定位于微管内腔稳定微管的蛋白质
Junya Kirima,Kazuhiro Oiwa
Junya Kirima
Genomics and proteomics studies in Chlamydomonas have revealed that an axoneme is composed of 200-600 types of proteins, including uncharacterized proteins collectively named flagellar-associated proteins (FAPs). Nine FAPs contain the EF-ha...
Daiki Takahashi,Hiroaki Suzuki,Yasumasa Kakei et al.
Daiki Takahashi et al.
The submandibular gland (SMG) is one of the major salivary glands that play important roles for variety of physiological functions, such as digestion of foods, prevention of infection, and lubrication of the mouth. Dysfunction of the SMG, o...
Bone Marrow Endothelial Cells Induce Immature and Mature B Cell Egress in Response to Erythropoietin [0.03%]
红细胞生成素诱导骨髓内皮细胞促进B淋巴细胞迁出反应
Takeshi Ito,Yoko Hamazaki,Akifumi Takaori-Kondo et al.
Takeshi Ito et al.
Bone marrow stromal cells, including endothelial cells and mesenchymal stromal cells, support the maintenance, differentiation, and retention of hematopoietic stem and precursor cells under steady state conditions. At the onset of an emerge...
Deltamethrin Increases Neurite Outgrowth in Cortical Neurons through Endogenous BDNF/TrkB Pathways [0.03%]
氯氟醚酚通过内源性BDNF/TrkB途径促进皮质神经元的轴突生长
Daisuke Ihara,Mamoru Fukuchi,Momoko Katakai et al.
Daisuke Ihara et al.
Deltamethrin (DM), a type II pyrethroid, robustly increases brain-derived neurotrophic factor (Bdnf) expression and has a neurotrophic effect in primary cultures of rat cortical neurons. In this study, we investigated the effect of DM on ne...
The Position of the GFP Tag on Actin Affects the Filament Formation in Mammalian Cells [0.03%]
GFP标签在肌动蛋白上的位置影响哺乳动物细胞中的丝状形成
Akira Nagasaki,Saku T Kijima,Tenji Yumoto et al.
Akira Nagasaki et al.
Actin, a major component of microfilaments, is involved in various eukaryotic cellular functions. Over the past two decades, actin fused with fluorescent protein has been used as a probe to detect the organization and dynamics of the actin ...
MiR-29a and miR-652 Attenuate Liver Fibrosis by Inhibiting the Differentiation of CD4+ T Cells [0.03%]
microRNA-29a和microRNA-652通过抑制CD4+T细胞分化来削弱肝纤维化的作用机制研究
Ji Xuan,Shu-Lin Guo,Ang Huang et al.
Ji Xuan et al.
Background: Liver fibrosis is the response of liver diseases that puzzles patients. MiRNAs were involved in the regulating processes of liver fibrosis. This study aims to investigate the effects of ARRB1 mediated by miR-2...
Drosophila DOCK Family Protein Zizimin Involves in Pigment Cell Differentiation in Pupal Retinae [0.03%]
果蝇DOCK家族成员Zizimin调控 pupal视网膜色素细胞分化功能研究
Fumito Ozasa,Kazushige Morishita,Ngoc Anh Suong Dang et al.
Fumito Ozasa et al.
The dedicator of cytokinesis (DOCK) family proteins are known as one of guanine nucleotide exchange factors (GEFs), that contribute to cellular signaling processes by activating small G proteins. Although mammalian Zizimin is known to be a ...