Recurrent Cutaneous Mycobacterium chelonae Infection With an IgM-Predominant Antibody Response in DiGeorge Syndrome [0.03%]
DiGeorge综合征患者出现反复皮肤分枝杆菌（海龟分支杆菌）感染及IgM为主的抗体应答反应病例报告
Makoto Kondo,Sho Mori,Koji Habe et al.
Makoto Kondo et al.
A young girl with DiGeorge syndrome developed recurrent cutaneous infection caused by Mycobacterium chelonae infection while receiving immunosuppressive therapy. Immunological evaluation demonstrated reduced T-cell proportions and impaired ...
Melanoma Dissemination Through Bullous Solar Elastosis: Previously Undescribed Pattern of Cancer Dissemination [0.03%]
通过 solar elastosis 引起的 bulla 播散性黑色素瘤——一种新的癌细胞播散方式
Ken Horisaki,Keisuke Goto,Arata Tsutsumida et al.
Ken Horisaki et al.
Metastasis can be classified into three forms based on the route of spread: lymphatic, hematogenous, and seeding within body cavities. We report a case of melanoma exhibiting seeding/dissemination around the primary site through bullous sol...
A Case of Annular Pustular Psoriasis Possibly Triggered by Cabozantinib and Edoxaban During Nivolumab Therapy [0.03%]
尼伏单抗治疗期间卡博替尼和艾多沙班诱发的环状脓疱型银屑病一例
Mana Nagatake,Hiroto Horikawa,Risa Kakuta et al.
Mana Nagatake et al.
Efficacy and Cosmetics of Secondary Intention Healing for Facial Skin Cancer: A Single-Center Retrospective Study [0.03%]
一期愈合治疗面部皮肤癌的有效性和美观性：单中心回顾性研究
Arisa Kimura,Takayuki Ishii,Naohito Hatta
Arisa Kimura
Reconstruction after facial skin cancer excision requires balancing oncologic safety with cosmetic outcomes. Secondary intention healing (SIH) is a simple and cost-effective wound management approach that avoids complex reconstruction and p...
Erythropoietic Protoporphyria and Surgery: A Case of Successful Mastectomy With Perioperative Light Shielding Strategies Based on Light-Induced Hemolytic Threshold Assessment [0.03%]
基于光致溶血阈值评估的围术期遮光策略在红细胞生成原卟啉症患者乳癌根治术中的应用
Fumika Tateishi,Naoya Murayama,Ruri Nakamuta et al.
Fumika Tateishi et al.
A 50-year-old female patient was referred to our department for consultation regarding perioperative management of breast cancer surgery. She had a history of photosensitivity since childhood and was diagnosed with erythropoietic protoporph...
A Case of Tsutsugamushi Mite Infestation With Multiple Larvae Visibly Attached to the Skin [0.03%]
恙螨侵袭伴多只若虫附着于皮肤的病例报告
Ai Yoshizaki,Yasuo Wada,Masako Andoh et al.
Ai Yoshizaki et al.
Immunohistochemistry Revealed Distinct IL-36γ Localization Among Different Skin Diseases [0.03%]
免疫组化显示IL-36γ在不同皮肤病中的定位不同
Megumi Kishimoto,Miho Kimura-Sashikawa,Mayumi Komine
Megumi Kishimoto
IL-36γ is highly expressed in psoriatic skin lesions and promotes neutrophil infiltration through the induction of neutrophil chemotactic chemokines. While IL-36γ has been established to play an important role in the pathogenesis of psori...
Efficacy of Minimal Blistering Dose-Based Versus Conventional Excimer Laser Therapy for Vitiligo [0.03%]
基于最小起疱剂量的准分子激光治疗与传统准分子激光治疗白癜病房的效果比较
Aya Yamamoto,Yuki Enomoto,Mai Sakurai et al.
Aya Yamamoto et al.
Excimer laser therapy is an established treatment for vitiligo, but the optimal irradiation protocol remains unclear. Irradiation based on the minimal blistering dose (MBD) was recently proposed, but its efficacy relative to conventional pr...
Tapinarof as a Therapeutic Aryl Hydrocarbon Receptor-Modulating Agent in the Treatment of Atopic Dermatitis [0.03%]
作为芳香烃受体调节剂的塔吡纳罗夫在特应性皮炎治疗中的作用
Gaku Tsuji,Yoko Fuyuno,Koji Kawamura et al.
Gaku Tsuji et al.
Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL-4 and IL-13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics ...
Persistent Blood Dioxins and Sensory Impairment Assessed by Quantitative Sensory Testing in 115 Yusho Patients 57 Years After Exposure [0.03%]
越堡症患者暴露二十五年以后的体内持久性二噁英污染及其感觉功能障碍-定量的感觉功能检查结果分析
Miwa Ashida,Takeshi Nakahara,Hiroyuki Murota
Miwa Ashida
Yusho patients continue to experience sensory symptoms such as pruritus and numbness even decades after dioxin exposure. However, objective assessment of long-term sensory impairment remains limited. Using a minimally invasive quantitative ...