Importance of molecular cell biology investigations in human medicine in the story of the Hutchinson-Gilford progeria syndrome [0.03%]
霍奇金-吉尔福德早老症故事中人类医学分子细胞生物学研究的重要性
Ivan Raška
Ivan Raška
Ranged among laminopathies, Hutchinson-Gilford progeria syndrome is a syndrome that involves premature aging, leading usually to death at the age between 10 to 14 years predominatly due to a myocardial infarction or a stroke. In the lecture...
Mojmír Mach
Mojmír Mach
A meta-analysis of medicinal plants to assess the evidence for toxicity [0.03%]
一项关于药用植物的荟萃分析：评估其毒性的证据
Sarah Chen,Amandio Vieira
Sarah Chen
Toxicity of phytochemicals, plant-based extracts and dietary supplements, and medicinal plants in general, is of medical importance and must be considered in phytotherapy and other plant uses. We show in this report how general database ana...
Effect of pomiferin administration on kidney ischaemia-reperfusion injury in rats [0.03%]
pomiferin对大鼠肾脏缺血再灌注损伤的保护作用
Lenka Bartošíková,Jiří Nečas,Tomáš Bartošík et al.
Lenka Bartošíková et al.
The aim of the study was to analyse protective effects of different doses of pomiferin in therapy of reperfusion injury. Rats were randomly divided into five groups (n=10). One group was intact. Three medicated groups and one placebo group ...
Miloň Tichý,Radka Valigurová,Radomír Cabala et al.
Miloň Tichý et al.
Toxicity of perfluorinated carboxylic acids with carbon chain C(8) to C(12) were tested with oligochaeta Tubifex tubifex. Toxicity was evaluated as the exposure time ET(50) from onset of damage of the oligochaeta in saturated aqueous soluti...
Protective effect of manganese in cadmium-induced hepatic oxidative damage, changes in cadmium distribution and trace elements level in mice [0.03%]
锰对镉致小鼠肝脏氧化损伤的保护作用及尿中镉分布和微量元素水平的变化规律
Vladislav Eybl,Dana Kotyzová
Vladislav Eybl
Oxidative tissue damage is considered an early sign of cadmium (Cd) toxicity and has been linked with carcinogenesis. Manganese(II)-at low doses, was found to act as a potent antioxidant against oxidative stress in different in vitro system...
Michal Dubovický
Michal Dubovický
Individual characteristics of human nature (e.g. introversion, extroversion, mood, activity, adaptability, aggressiveness, social ability, anxiety) do not need to be primarily innate. They can be determined by the action of various influenc...
Jaroslav Květina,Jithinraj Edakkanambeth Varayil,Shahzad Marghoob Ali et al.
Jaroslav Květina et al.
Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review of preclinical EGG. Our group recentl...
DNA and histone deacetylases as targets for neuroblastoma treatment [0.03%]
DNA和组蛋白去乙酰酶作为神经母细胞瘤治疗的靶点
Marie Stiborová,Jitka Poljaková,Tomáš Eckschlager et al.
Marie Stiborová et al.
Neuroblastoma, a tumor of the peripheral sympathetic nervous system, is the most frequent solid extra cranial tumor in children and is a major cause of death from neoplasia in infancy. Still little improvement in therapeutic options has bee...
Viktor Bauer
Viktor Bauer