Renata Večeřová,Aleš Panáček,Milan Kolář
Renata Večeřová
Objective: The aim was to evaluate the antibacterial effect of silver nanoparticles on anaerobic bacteria. Material and methods: The mi...
Ondřej Holý,Jana Vlčková,Lenka Janoušková et al.
Ondřej Holý et al.
Diphtheria, tetanus and pertussis are very serious diseases threatening the lives of children and adults. However, these diseases are preventable by vaccination. After the World Health Organization was founded in 1946, its experts rapidly d...
Hana Suchánková,Zuzana Matušková,Alena Vanduchová
Hana Suchánková
Therapeutic drug monitoring (TDM) is a dosage individualization strategy that helps to minimize toxicity whilst maximizing the efficacy of an agent. For many years, beta-lactam antibiotics were not considered ideal candidates for TDM due to...
[The use of MALDI-TOF MS for direct identification of bacteria in clinical specimens] [0.03%]
基质辅助激光解析电离飞行时间质谱技术直接鉴定临床标本中细菌的研究应用
Radka Tarabová,Jan Bardoň
Radka Tarabová
MALDI-TOF MS is a method enabling rapid identification of bacteria. This is also important for early initiation of adequate antibiotic therapy in patients with infections. In this review, various methods for direct detection of bacteria in ...
Simona Frydrychová,Vanda Boštíková,Pavel Boštík
Simona Frydrychová
Natural killer (NK) cells represent an important component of the human body´s defense against viruses, bacteria and other intra-cellular pathogens as well as against tumor cells. NK cells are capable of very fast response without prior se...
Lenka Hobzová,Miroslav Špliňo,Roman Chlíbek et al.
Lenka Hobzová et al.
The article provides information on an outbreak of infection with a strain of Staphylococcus aureus resistant to gentamicin (SARG) and a hyperproducer of enterotoxins A and D at a neonatal intensive care unit of the University Hospital in H...
[Lactic acidosis due to metformin accumulation complicating acute gastroenteritis] [0.03%]
[急性胃肠炎伴二甲双胍蓄积导致的乳酸性酸中毒]
Olga DŽupová,Jana Kulichová
Olga DŽupová
Lactic acidosis is the most severe adverse effect associated with metformin therapy of type 2 diabetes mellitus. The risk increases in patients with impaired renal function, most commonly due to diabetic nephropathy, and may be augmented wh...
Michal Holub,Ondřej Beran
Michal Holub
The article discusses new definitions for sepsis and septic shock called Sepsis-3. The definitions are put in the historical and factual context of the 1992 definition and their extended 2003 version. Also mentioned are potential impacts on...
Ľubomír Skladaný,Silvia Kasová,Anna Purgelová et al.
Ľubomír Skladaný et al.
Aim of study: Spontaneous bacterial peritonitis (SBP) is the most frequent infectious complication of liver cirrhosis with serious consequences. Initially, SBP is always treated with empirical, not targeted, antibiotic th...
[Is it necessary to revaccinate against hepatitis B virus when the titer of anti-HBs drops below 10 IU/L?] [0.03%]
乙肝表面抗体滴度低于10IU/L时有无必要加强接种乙肝疫苗？
Pavel Polák,Petr Husa,Petr Smejkal et al.
Pavel Polák et al.
Viral hepatitis B still represents a major epidemiological issue worldwide. After recombinant vaccine administration, a titer of anti-HBs antibodies ≥ 10 IU/L has long been considered to be seroprotective. Persons without this antibody lev...