[Production of anthracene derivatives in elicited tissue cultures of Rheum palmatum L] [0.03%]
[以诱导培养组织生产掌叶大黄的蒽衍生物]
M Kasparová,T Siatka
M Kasparová
With a few exceptions, the characteristic problem of cultivation of plant explants in in vitro cultures is a low production of secondary metabolites by these cultures. One of the methods, which can achieve an increase in the production of n...
[Chalcones and their heterocyclic analogs as potential antifungal chemotherapeutic agents] [0.03%]
[作为潜在抗真菌化疗剂的查耳酮及其杂环类似物]
V Opletalová,D Sedivý
V Opletalová
Chalcones and their heterocyclic analogues show various biological effects, e.g. anti-inflammatory, antitumour, antibacterial, antituberculous, antiviral, antiprotozoal, gastroprotective, and others. The present review discusses in greater ...
M Smiesko,M Remko
M Smiesko
The application of the pharmacophore concept to design new drugs is discussed. The focus is on the application of computer-assisted drug design methods (CADD) in the discovery of new leads.
[Preparation and antineoplastic activity of acylhydrazones of R- and S-usnic acid] [0.03%]
[R-和S-乌斯酸衍生物的合成及其抗肿瘤活性]
B Proksa,A Proksová
B Proksa
Hydrazones of R- and S-usnic acid were prepared by condensation of the appropriate enantiomer of usnic acid with hydrazides of aromatic acids. Prepared compounds were characterized by spectral methods. Reaction kinetic was studied with capi...
[The oyster mushroom (Pleurotus ostreatus) effectively prevents the development of atherosclerosis in rabbits] [0.03%]
[真姬菇能有效防止兔动脉粥样硬化的发展]
P Bobek,S Galbavý
P Bobek
The addition of 10% dried fruiting bodies of the oyster mushroom (Pleurotus ostreatus) to the diet containing 1% of cholesterol reduced serum cholesterol levels by 65% and cholesterol content in the liver, heart, long extensor muscle and ao...
K Ducková,J Kucera
K Ducková
The present paper investigates drugs and polymers intended for the impregnation of textile carriers intended for use as wound covers. Their suitability was evaluated on the basis of the evaluation of the antimicrobial efficacy of a combinat...
[Use of redox polymers for insulin labeling with technetium (99mTc)] [0.03%]
红氧化聚合物标记胰岛素的研究（~(99m)Tc）
P Komárek,I Kleisner,M Konopková et al.
P Komárek et al.
The paper describes a method for porcine insulin labelling with technetium(99mTc). When preparing this peptide, an insoluble redox polymer on the basis of cross-linked dextran (RP G25-IDA) was used for labelling. The prepared kits were labe...
[The effect of health care reform in Germany on the pharmacist's role in pharmacotherapy] [0.03%]
德国医药卫生体制改革对药师药学作用的影响
P Ginzelová,K H Kugler,J Solich
P Ginzelová
The present paper describes the pharmacist's role in Germany during the health-service reform and shows his prospects within pharmacological therapy and his role in contemporary modern society. However, emphasis is placed on the out-patient...
[Advances in the development of new antitubercular agents from a group of 5-membered heterocyclic compounds containing various heteroatoms] [0.03%]
含各种杂原子的五元杂环类抗结核药物研究进展
K Waisser,L Drhová
K Waisser
Tuberculosis and other antimycobacterial diseases are considered to be one of the most important problems of the health service at present. Since 1985, and in particular in the 1990s, a search for new structures of antimycobacterial substan...
[Preparation and antiinflammatory activity of selected aqua-(aryloxyacetate) zinc complexes] [0.03%]
[某些 aryloxyacetate 锌配合物的合成及其抗炎活性]
M Blahová,J Sokolík,I Tumová et al.
M Blahová et al.
Mononuclear aqua(aryloxyacetato)zinc(II) complexes of the composition [Zn(H2O)2(ROCH2COO)2] (R = phenyl, o-, m-, p-tolyl) were prepared as potential anti-inflammatory agents. The results of elemental analysis and parameters of IR spectra al...