Prospects of сomplex pharmaceutical composition application for pharmacological correction of metabolic syndrome [0.03%]
复杂药物制剂在代谢综合征药理学矫正中的应用前景
Kateryna Kalko,Nadia Dukhnich,Oksana Mishchenko et al.
Kateryna Kalko et al.
Metabolic syndrome (MetS) is a symptomatic complex characterized by insulin resistance, impaired prooxidant-antioxidantbalance of the body with the development of subchronic inflammation, and dyslipidemia. The aim of the study is to investi...
Potential impact on mental health in patients with treatment-resistant schizophrenia - clozapine augmentation with long-acting parenteral antipsychotics: a case series [0.03%]
难治性精神分裂症患者的潜在影响-氯氮平与长效抗精神病药物联用：病例系列研究
M Nováková,T Hammer,E Nováková et al.
M Nováková et al.
Introduction: The rate of pharmacoresistance among in patients diagnosed with schizophrenia is around 30%. Clozapineis the drug of choice for these patients; however, an adequate response to treatment doesn't always occur...
Brief insight into the in silico properties, structure-activity relationships and biotransformation of fruquintinib, an anticancer drug of a new generation containing a privileged benzofuran scaffold [0.03%]
新型抗癌药物fruquintinib的计算性质、构效关系及生物转化的简要分析，该药物含有privileged苯并呋喃骨架
Dominika Nádaská,Lucia Hudecova,Gustáv Kováč et al.
Dominika Nádaská et al.
Current trends in drug design notably consider so-called privileged scaffolds as the core structural fragments with decisive impact on affinity to properly chosen biological targets, potency, selectivity and toxicological characteristics of...
Anetta Jedličková
Anetta Jedličková
The conduct of clinical trials of investigational medicinal products brings, in clinical research with the participation of human subjects, various ethical concerns, which should be competently addressed. In clinical research, adherence to ...
Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial [0.03%]
两种乳杆菌作为辅助疗法用于肠易激综合征的治疗：一项随机对照试验
Sadeel A Shanshal,Mohammad H Alsaaty,Harith Al-Qazaz et al.
Sadeel A Shanshal et al.
Alleviating the symptoms of irritable bowel syndrome (IBS) through the addition of probiotics to the treatment of IBS patients appears to be promising. The present randomized clinical trial seeks to assess the efficacy of a multi-strain pro...
Hyperferritinemia as a factor associated with poor prognosis in COVID-19 patients [0.03%]
高血清铁蛋白水平作为COVID-19患者预后不良的相关因素
Nuhad Mohammed Al-Dulaimi,Mahmood Jassim Mohammed,Saad T Mutlk et al.
Nuhad Mohammed Al-Dulaimi et al.
Worldwide, hundreds of millions of people have been infected with COVID-19 since December 2019; however, about 20% or less developed severe symptoms. The main aim of the current study was to assess the relationship between the severity of C...
Preparation and evaluation of spray-dried inhalable microparticles from carrier mixtures [0.03%]
来自载体混合物的喷雾干燥可吸入微粒的制备和评估
Andrea Peštálová,Karolína Molatová,Jan Gajdziok
Andrea Peštálová
The formulation of microparticles composed of a mixture of carriers represents an innovative approach for lung drug delivery of dry powder. The carriers used can significantly influence the properties of the microparticles, such as size, sh...
Therapeutic monitoring of antipsychotics with a focus on lurasidone and its dosing [0.03%]
以鲁拉西酮及其剂量为重点的抗精神病药物的治疗监测
Z Strašilová,M Turjap,J Juřica
Z Strašilová
Dose-response relationships are not fully understood for antipsychotics. Especially in the case of multimodal antipsychotics, these relationships cannot be simplified to the level of dopaminergic receptor occupancy alone. In general, for mo...
Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial [0.03%]
两种乳杆菌作为辅助治疗干预肠易激综合症：一项随机实验
Sadeel A Shanshal,Mohammad H Alsaaty,Harith Al-Qazaz et al.
Sadeel A Shanshal et al.
Alleviating the symptoms of irritable bowel syndrome (IBS) through the addition of probiotics to the treatment of IBS patients appears to be promising. The present randomized clinical trial seeks to assess the efficacy of a multi-strain pro...
Hyperferritinemia as a factor associated with poor prognosis in COVID-19 patients [0.03%]
高血清铁蛋白水平作为COVID-19患者预后不良的关联因素
Nuhad Mohammed Al-Dulaimi,Mahmood Jassim Mohammed,Saad T Mutlk et al.
Nuhad Mohammed Al-Dulaimi et al.
Worldwide, hundreds of millions of people have been infected with COVID-19 since December 2019; however, about 20% or less developed severe symptoms. The main aim of the current study was to assess the relationship between the severity of C...