Anticonvulsant biotargets of digoxin: in silico study and in vivo verification [0.03%]
地高辛的抗癫痫生物靶点：基于计算的研究及体内验证
Vadym Tsyvunin,Hanna Severina,Sergii Shtrygol et al.
Vadym Tsyvunin et al.
One of the promising ways to control multidrug-resistant epilepsy may be to use, in addition to traditional antiepileptic drugs (AEDs), medicines from other pharmacological groups - the so-called "non-antiepileptic" drugs. Among such drugs,...
Current pharmacotheraupeutical options of lower urinary tract symptoms [0.03%]
目前膀胱过度活动症及其他下尿路症状的药物治疗选择
Marcela Fontana
Marcela Fontana
Lower urinary tract symptoms (LUTS) represent a wide unit with multifactorial etiology, and therefore, treatment is not uniform. In most patients with LUTS, pharmacotherapy is an effective option for managing these symptoms, thereby improvi...
Kateřina Štechová
Kateřina Štechová
In January 2025, 103 years have passed since the injection of insulin saved the life of the first patient with type 1 diabetes mellitus. The aim of the article is to familiarize readers with current insulin therapy, which is an essential tr...
Klára Kotyková
Klára Kotyková
In practice, it is quite common to encounter patients who come to the pharmacy because of problems associated with chronic venous disease. They complain, for example, of a feeling of heavy legs, tingling, pain or swelling of the lower limbs...
Martin Doseděl,Tereza Hendrychová,Josef Malý
Martin Doseděl
Diarrhea is a common symptom that is suitable for self-treatment in a significant proportion of patients. The aim of this article was to summarize current knowledge and therapeutic options regarding the management of diarrhea in the context...
Zuzana Hajšelová
Zuzana Hajšelová
With the rising prevalence of allergic diseases also rises a demand for safe and effective options for self-medication. The main aim of this article is focused on various types of self-medication using over-the counter preparations and dist...
Self-treatment of acute cough in adults and adolescents older than 12 years [0.03%]
成人和12岁以上青少年急性咳嗽的自我药疗
Lenka Ťupová,Tereza Hendrychová,Josef Malý
Lenka Ťupová
Acute cough is a frequent symptom accompanying upper respiratory tract infections and acute bronchitis. In order to start self-treatment, a thorough consideration of its suitability is necessary. A systematic algorithm can help pharmacists ...
Possibilities of mixing powder mixtures for capsules using three-dimensional mixer devices in pharmacy practice [0.03%]
三维混合器设备在药房实践中混合粉剂以制备胶囊的可能性研究
Ondřej Černý
Ondřej Černý
Preparing oral powders for filling of hard capsules is one of the basic activities in pharmacies. One of the key operations that affects the resulting homogeneity of the substances in the mixture is the mixing process. Until recently, most ...
Adherence to the Pharmacist's Protocol of sore throat symptomatic treatment in Ukraine and problems of harmonization with international guidelines [0.03%]
乌克兰咽痛对症治疗的药师协议的依从性及其与国际指南协调的问题
Viktoriia Propisnova,Svitlana Misiurova
Viktoriia Propisnova
Background: Good pharmaceutical counselling in the sore throat symptomatic treatment is an important component of the health care first line, timely detection of infectious diseases, provision of qualified assistance, pre...
Covalent drugs [0.03%]
共价药物
Marta Kučerová
Marta Kučerová
Covalent drugs are substances capable of forming a reversible or an irreversible covalent bond with a macromolecular target in the body. Despite the risk of adverse reactions in the organism, the design of such agents has become a trend ove...