Preformulation design of PLGA particulate system for multi-day drug delivery of the antidepressant mirtazapine [0.03%]
用于抗抑郁药米塔扎平多日输送的PLGA颗粒系统的预配方设计研究
Martina Holická,Jan Muselík,Martina Kejdušová et al.
Martina Holická et al.
In this experimental study, the biodegradable polylactide-co-glycolide (PLGA) microparticles (MP) loaded with the insoluble antidepressant mirtazapine were prepared by the simple o/w solvent evaporation method. The formation involved intrin...
Phenylpropanoids and flavonoid from Helichrysum petiolare Hilliard & B. L. Burtt [0.03%]
Helichrysum petiolare Hilliard et B.L.Burtt的苯丙素和黄酮类成分研究
Renata Kubínová,Marcela Nejezchlebová,Markéta Gazdová et al.
Renata Kubínová et al.
The phytochemical analysis of a methanolic extract from Helichrysum petiolare Hilliard & B. L. (Asteraceae) confirmed the content of phenylpropanoids and flavonoids. Five secondary metabolites were isolated using preparative HPLC, namely co...
Antibiotics and the quality indicators for outpatient antibiotic use in Slovakia [0.03%]
抗生素及斯洛伐克门诊抗生素使用的质量指标
Tomáš Tesař,Lucia Masaryková,Slávka Porubcová et al.
Tomáš Tesař et al.
The aims of this study was to compare the data on the consumption of antibiotics in the outpatient care sector for Slovakia from 2019 to 2020 and to calculate quality indicators for outpatient antibiotic use. The data source on the consumpt...
The effect of meloxicam and cryopreserved placenta extract on initial inflammatory response - an experimental study [0.03%]
美洛昔康和冷冻胎盘提取物对初始炎症反应的影响-一项实验研究
Fedir V Hladkykh
Fedir V Hladkykh
Alteration is the first phase of the inflammatory process triggering the entire cascade of inflammation and causing destructive changes in the affected tissues. Therefore, suppression of inflammation at this point is essential for the succe...
Antiadhesive, antibiofilm and dispersion activity of biosurfactants isolated from Bacillus amyloliquefaciens 3/22 [0.03%]
来源于枯草芽孢杆菌3/22的生物表面活性剂的防粘附、抗菌膜和分散作用
Karolína Englerová,Radomíra Nemcová,Zdenka Bedlovičová et al.
Karolína Englerová et al.
The aim of this work was to monitor the potential antibiofilm properties of biosurfactants (BS) isolated from Bacillus amyloliquefaciens 3/22 against biofilm formation of the indicator strain Staphylococcus aureus CCM 4223. In this work, th...
Telacebec (Q203): Is there a novel effective and safe anti-tuberculosis drug on the horizon? [0.03%]
telacebec（Q203）：即将来来的新型有效且安全的抗结核病药物？
Ivan Malík,Jozef Čižmárik,Gustáv Kováč et al.
Ivan Malík et al.
High prevalence and stronger emergency of various forms of drug-resistant tuberculosis (DR-TB), including the multidrug-resistant (MDR-TB) as well as extensively drug-resistant (XDR-TB) ones, caused by variously resistant Mycobacterium tube...
Use of droplet-based microfluidic techniques in the preparation of microparticles [0.03%]
基于液滴的微流控技术在制备微粒中的应用
Martina Naiserová,Jakub Vysloužil,Kateřina Kubová et al.
Martina Naiserová et al.
Microparticles are widely used in myriad fields such as pharmaceuticals, foods, cosmetics, and other industrial fields. Compared with traditional methods for synthesizing microparticles, microfluidic techniques provide very powerful platfor...
Pharmaceutical Art and Peculiarities in the Latin Dissertation De phthisi (On Tuberculosis) from 1679 by Slovak Physician Matúš Palumbini [0.03%]
斯洛伐克 physician Matúš Palumbini 1679年拉丁文论文《论肺结核》中的药学艺术及特色
Mária Bujalková,Nora Malinovská
Mária Bujalková
The objective of the article is to present and analyse one part of the printed dissertation De phthisi (On Tuberculosis) by Matúš Palumbini, namely chapter VIII, Curatio perfecta (Perfect Treatment). Treatment of diseases in the 17th ...
68Ga-DOTATOC [0.03%]
68镓-DOTATOC
Michal Budinský,Petr Vyšinský,Stanislav Synek et al.
Michal Budinský et al.
The radiopharmaceutical 68Ga-DOTATOC represents the latest radiopharmaceutical in the diagnosis of a neuroendocrine tumor with somatostatin receptor overexpression. Technological and economic difficulties of preparing and quality control of...
The role of vitamin D in primary and secondary prevention in orthopaedic patients [0.03%]
维生素D在骨科疾病初发和继发预防中的作用
Michal Čečrle,Norbert Didič,Milada Halačová et al.
Michal Čečrle et al.
The article discusses the effect of vitamin D on primary and secondary prevention of fractures and its effect on conditions after selected orthopaedic procedures. Fractures can be divided into traumatic, fatigue and pathological according t...