Mária Kolesárová,Ondrej Franko,Dalibor Kolesár et al.
Mária Kolesárová et al.
The aim of the study was to point out the contribution of new invasive therapeutic procedures in the treatment of advanced stages of Parkinson's disease (PD) in comparison with classical oral pharmacotherapy. Data originated from a group of...
Aus Tariq Ali,Faisal Al-Ani,Osamah Al-Ani
Aus Tariq Ali
As a result of the dramatic increase in the prevalence of overweight and obesity among children, childhood obesity is one of the most critical global public health challenges of the 21st century. Weight gain occurs when energy intake exceed...
Entry and competition of retail pharmacies: A case study of OTC drugs sales and ownership deregulation1 [0.03%]
零售药店的进入与竞争研究——来自处方药销售和所有权管制放松的证据
Matúš Bilka,António Portugal Duarte,Martin Lábaj
Matúš Bilka
This study provides new empirical evidence on the changes in competition and entry decisions of pharmacies after regulatory changes. It investigates the development of the retail pharmacy market in Portugal, which underwent major regulatory...
Contribution to the concept of polypharmacy II. Prescription and use of medicines [0.03%]
论多重用药概念的贡献(二)处方情况和药物使用状况
Jozef Kolář,Tünde Ambrus,Dominik Grega et al.
Jozef Kolář et al.
The study defines the basic terminological structure associated with the concepts of prescribing and medication use in relation to polypharmacy. Correctly naming the current prescription or use of a medication by a particular patient allows...
Medicinal mushrooms Ophiocordyceps sinensis and Cordyceps militaris [0.03%]
药用蘑菇Ophiocordyceps sinensis 和Cordyceps militaris
Lucia Ungvarská Maľučká,Anna Uhrinová,Patricia Lysinová
Lucia Ungvarská Maľučká
The main component of Ophiocordyceps sinensis and Cordyceps militaris extracts are polysaccharides. These are natural biopolymers that represent a large class of biologically active components. These contribute to their pharmacological acti...
Tomáš Bílik,Miroslava Pavelková,Kateřina Kubová et al.
Tomáš Bílik et al.
The presented review article is a compilation of several foreign reviews and experimental papers, as well as several authority guidelines, which deal with the phenomenon of dose dumping of solid dosage forms with modified drug release. The ...
Contribution to the concept of polypharmacy I. Etymological notes and characteristics [0.03%]
多药治疗概念的贡献 I. 词源注释和特征
Jozef Kolář,Tünde Ambrus,Dominik Grega et al.
Jozef Kolář et al.
The contribution captures three basic concepts of the term polypharmacy. The analysis of four bibliographic databases demonstrates the importance of the correct and uniform use of terminology. It also approximates the most common numerical ...
The efficacy of triazavirin (riamilovir)-based treatment for coronavirus disease 2019 (COVID-19) in clinical trials and preliminary practical experiences [0.03%]
三氮唑灵(利马洛维)为基础的治疗在临床试验和初步实际经验中对2019冠状病毒疾病(COVID-19)的有效性
Ivan Malík,Gustáv Kováč,Lucia Hudecova
Ivan Malík
Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has plagued the human population as 2019 turned into 2020, when first cases were confirmed to be infected with the pathogen in Wuhan ...
Promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide: dose-dependent study and evaluation of anticonvulsant action spectrum in vivo and in silico [0.03%]
有前景的抗惊厥化合物N-[(2,4-二氯苯基)甲基]-2-(2,4-二氧代-1H-喹唑啉-3-基)乙酰胺:剂量依赖性研究及在体内和计算机模拟中的抗惊厥作用谱评价
Sergiy Shtrygol,Sergiy Zalevskyi,Mariia Mishchenko et al.
Sergiy Shtrygol et al.
The anticonvulsant spectrum of the original promising anticonvulsant N-[(2,4-dichlorophenyl) methyl]-2-(2,4-dioxo-1H-quinazolin-3-yl) acetamide was studied. The compound had a pronounced anticonvulsant effect, significantly reducing the mor...
The effect of non-steroidal anti-inflammatory drugs with different mechanisms of action on the body temperature and cyclooxygenase pathway of the arachidonic acid cascade on the model of acute general cooling (air hypothermia) in rats [0.03%]
不同作用机制的非甾体抗炎药对急性全身冷却(空气低体温)大鼠模型的体温和花生四烯酸级联中环氧化酶途径的影响
Sergiy Shtrygol,Olga Tovchiga,Olesia Kudina et al.
Sergiy Shtrygol et al.
NSAIDs are promising agents for preventing cold injury (frigoprotectors). The influence of prophylactic administration of the non-selective COX inhibitor diclofenac sodium (7 mg/kg) and the highly selective COX-2 inhibitor etoricoxib (5 mg/...