Chlormethine Gel for the Treatment of Mycosis Fungoides (Cutaneous T-cell Lymphoma) in Canada [0.03%]
加拿大氯甲基磺酸酯凝胶治疗蕈样肉芽肿(皮肤T细胞淋巴瘤)
Robert Gniadecki,Emilia Paron
Robert Gniadecki
Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), representing almost 50% of all lymphomas arising in the skin. There is an unmet need in the treatment of MF in Canada, as current available therapies for ea...
Austinn C. Miller,Susuana Adjei,Laurie A. Temiz et al.
Austinn C. Miller et al.
Virtually any antibiotic can be used in dermatology given the broad range of conditions treated. With the widespread use of antibiotics and the rapid emergence of resistant organisms, it is important to understand the mechanisms at play tha...
Abrahim Abduelmula,Brian D Rankin,Asfandyar Mufti et al.
Abrahim Abduelmula et al.
Atopic dermatitis (AD) is a common, chronic, recurrent, immune-mediated inflammatory skin disease. Targeted treatment options remain limited. Tralokinumab (Adtralza®) is a promising, new systemic therapy that inhibits interleukin-13. It wa...
Review
Skin therapy letter. 2023 Jan;28(1):1-6. DOI: 2023
Abdulhadi Jfri,Ali Alajmi,Mohammad Alazemi et al.
Abdulhadi Jfri et al.
Acne vulgaris is a troubling skin disease known to have both physiologic and psychological effects on patients. Acne scars, a frequent complication, can further impact patients' quality of life. Scars result from an impairment in the healin...
Selective TYK2 Inhibition in the Treatment of Moderate to Severe Chronic Plaque Psoriasis [0.03%]
选择性TYK2抑制在中重度慢性斑块状银屑病治疗中的应用
Melinda J Gooderham,H Chih-Ho Hong,Ivan V Litvinov
Melinda J Gooderham
Moderate to severe chronic plaque psoriasis may be difficult to control using current therapies, which has led to development of a novel class of therapy, selective tyrosine kinase 2 (TYK2) inhibitors, to address this unmet need. Oral deucr...
Toxic Epidermal Necrolysis: A Review of Past and Present Therapeutic Approaches [0.03%]
毒性表皮坏死松解症：过去和现在的治疗方法回顾
Neha Singh,Mariana Phillips
Neha Singh
Toxic epidermal necrolysis (TEN) is an immune mediated, severe cutaneous adverse drug reaction characterized by epidermal detachment affecting greater than 30% body surface area. The mortality rate of TEN exceeds 20% and is usually caused b...
Review
Skin therapy letter. 2022 Sep;27(5):7-13. DOI: 2022
Extracorporeal Photopheresis and Its Use in Clinical Dermatology in Canada [0.03%]
体外光触疗法及其在加拿大皮肤科临床上的应用
François Lagacé,Elena Netchiporouk,Irina Turchin et al.
François Lagacé et al.
Extracorporeal photopheresis (ECP) is an immunomodulatory therapy that has been used for over 35 years to treat numerous conditions. ECP was initially approved by the US FDA in 1988 for the treatment of Sézary syndrome, a leukemic form of ...
Review
Skin therapy letter. 2022 Sep;27(5):1-6. DOI: 2022
Austinn C Miller,Susuana Adjei,Laurie A Temiz et al.
Austinn C Miller et al.
Actinic keratosis (AK) is a common precancerous condition found on chronically sun-damaged skin, particularly on the face, scalp, arms, and legs. Early and effective treatment of AKs is important to prevent progression to squamous cell carc...
Review
Skin therapy letter. 2022 Jul;27(4):4-7. DOI: 2022
Catherine Zip
Catherine Zip
Topical retinoids are recommended as first line therapy for the treatment of acne. Despite this recommendation, topical retinoids are underutilized, in part because of their tendency to cause cutaneous irritation. Tazarotene 0.045% lotion w...
Susuana Adjei,Austinn C Miller,Laurie A Temiz et al.
Susuana Adjei et al.
Tetracycline-class drugs have been used for first-line treatment of moderate-to-severe acne and rosacea for decades. Recently, a new third generation tetracycline, sarecycline, was US FDA-approved for the treatment of moderate-to-severe acn...