Optical coherence tomography for retinal imaging in multiple sclerosis [0.03%]
光学相干断层扫描在多发性硬化视网膜成像中的应用
Hanna Zimmermann,Timm Oberwahrenbrock,Alexander U Brandt et al.
Hanna Zimmermann et al.
Visual disturbances caused by inflammatory and demyelinating processes of the visual system, mainly in the optic nerve, are a common symptom in multiple sclerosis (MS). Optical coherence tomography (OCT) is a tool that is increasingly used ...
Use of transcranial magnetic stimulation in the treatment of selected movement disorders [0.03%]
经颅磁刺激在部分运动障碍治疗中的应用
Katlyn E Brown,Jason L Neva,Noah Mh Ledwell et al.
Katlyn E Brown et al.
Transcranial magnetic stimulation (TMS) is a valuable technique for assessing the underlying neurophysiology associated with various neuropathologies, and is a unique tool for establishing potential neural mechanisms responsible for disease...
Intravenous immunoglobulin for the treatment of Alzheimer's disease: current evidence and considerations [0.03%]
阿尔茨海默病的静脉用免疫球蛋白治疗：现有证据及考量因素
Christina Schindowski,Jürgen Zimmermann,Katharina Schindowski
Christina Schindowski
Alzheimer's disease (AD) is a devastating neurodegenerative form of dementia with increasing incidence rates in most countries. AD is characterized by amyloid plaques and neurofibrillary tangles in the brains of AD individuals accompanied b...
Optimal management of multiple sclerosis during pregnancy: current perspectives [0.03%]
多发性硬化症妊娠期的优化管理：目前的观点
Nadja Borisow,Friedemann Paul,Jan Dörr
Nadja Borisow
Multiple sclerosis (MS) is a common inflammatory demyelinating disorder of the central nervous system. It frequently affects females in their reproductive phase of life. Therefore, family planning, pregnancy, and breastfeeding are important...
Current and emerging treatments for relapsing multiple sclerosis in Argentinian patients: a review [0.03%]
阿根廷复发性多发性硬化症患者的当前和新兴治疗方法：综述
Juan I Rojas,Liliana Patrucco,Edgardo Cristiano
Juan I Rojas
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. Recent developments have led to newer therapeutic options for disease treatment. A few studies have reported MS prevalence rates between 12 and 20 per 100,000 i...
Robert Balazs
Robert Balazs
The worldwide increase in life expectancy is leading to an increase in age-dependent diseases, including nonfamilial, sporadic Alzheimer's disease (AD), which is the subject of this review. The etiology and pathophysiology of the disease is...
Identifying responders and nonresponders to interferon therapy in multiple sclerosis [0.03%]
识别多发性硬化症干扰素治疗应答者和非应答者
Luca Prosperini,Marco Capobianco,Costanza Giannì
Luca Prosperini
Interferon beta is a well established disease-modifying agent used for relapsing-remitting multiple sclerosis. Despite treatment, a relevant proportion of patients continue to experience clinical (ie, relapses, worsening of disability) and ...
Neurogenic overactive bladder in spinal cord injury and multiple sclerosis: role of onabotulinumtoxinA [0.03%]
脊髓损伤和多发性硬化症的神经源性膀胱过度活动症的肉毒杆菌毒素治疗研究进展
K D Ethans,A R Casey,R J Bard et al.
K D Ethans et al.
People with neurogenic overactive bladder from either multiple sclerosis or spinal cord injury often suffer significant morbidity and decreased quality of life. Here we review the pathophysiology of neurogenic overactive bladder and the imp...
Neurodegeneration in multiple sclerosis involves multiple pathogenic mechanisms [0.03%]
多发性硬化症的神经退行性疾病涉及多种致病机制
Michael C Levin,Joshua N Douglas,Lindsay Meyers et al.
Michael C Levin et al.
Multiple sclerosis (MS) is a complex autoimmune disease that impairs the central nervous system (CNS). The neurological disability and clinical course of the disease is highly variable and unpredictable from one patient to another. The caus...
Axonal transport and neurodegenerative disease: vesicle-motor complex formation and their regulation [0.03%]
轴浆运输与神经退行性疾病：囊泡-动力蛋白复合物的形成及其调节机制
Eric N Anderson,Joseph A White,Shermali Gunawardena
Eric N Anderson
The process of axonal transport serves to move components over very long distances on microtubule tracks in order to maintain neuronal viability. Molecular motors - kinesin and dynein - are essential for the movement of neuronal cargoes alo...